New pill for weight loss enters human testing

NCT ID NCT06562907

First seen Mar 25, 2026 · Last updated Jun 22, 2026 · Updated 16 times

Summary

This early-phase study tests a new oral drug called GS-4571 in healthy people, non-diabetic obese individuals, and non-obese people with type 2 diabetes. The main goals are to see how the drug moves through the body, how safe it is, and how food or acid-reducing drugs affect it. About 134 participants will take single or multiple doses, with some receiving a placebo. This is a safety and dosing trial, not yet testing if the drug works for weight loss.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OBESITY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • ICON

    RECRUITING

    Salt Lake City, Utah, 84124, United States

  • ICON Early Phase Services, LLC

    RECRUITING

    San Antonio, Texas, 78232, United States

  • Qps-Mra, Llc.

    RECRUITING

    Miami, Florida, 33143, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

GS-4571 (oral drug)

What this could lead to

If successful, this could lead to a new oral medication for weight management, potentially helping with obesity and type 2 diabetes.

What could go wrong

This is a very early Phase 1 trial focused on safety and dosing, not effectiveness. The drug may not work or could have side effects. Results may not apply to broader populations.

Conditions

The condition(s) this trial relates to.

obesity disorder type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.