Could a sleep hormone ease diabetic nerve damage?
NCT ID NCT07036796
First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time
Summary
This study investigates whether adding melatonin to standard diabetes care can improve symptoms of diabetic peripheral neuropathy, a common complication causing pain and numbness in the feet and hands. The trial includes 60 adults aged 40-75 with type 2 diabetes and diagnosed nerve damage. Researchers will measure changes in markers of oxidative stress and inflammation, as well as symptom scores, over the treatment period.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- melatonin, a hormone supplement with antioxidant and anti-inflammatory properties
- What this could lead to
- If it works, this could point toward a simple, low-cost supplement to help manage diabetic nerve damage and reduce pain or numbness.
- What could go wrong
- This is a small, early-phase trial with only 60 participants, so results may not apply widely. Melatonin can cause drowsiness and may interact with other medications.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ain Shams University hospital
RECRUITINGCairo, Egypt
Contact Phone: •••-•••-•••• Email: •••••@•••••
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