DIABETIC NEUROPATHY

This study tests whether a 12-week program of supervised foot and ankle exercises can help people with diabetes who have nerve damage in their feet. The exercises are done in groups at primary care clinics. Researchers will measure changes in symptoms, foot movement, and quality …

This study investigates whether adding melatonin to standard diabetes care can improve symptoms of diabetic peripheral neuropathy, a common complication causing pain and numbness in the feet and hands. The trial includes 60 adults aged 40-75 with type 2 diabetes and diagnosed ner…

This study tests a new type of shoe, called the LEEF-shoe, designed to prevent foot ulcers in people with diabetes and nerve damage. About 30 adults will wear both the LEEF-shoe and standard orthopedic shoes for several weeks to compare how well they relieve pressure on the feet.…

This study tests if special sensor-equipped insoles can help prevent foot ulcers from coming back in people with diabetes and nerve damage. About 400 high-risk participants will use the insoles alongside standard care or just standard care alone. The goal is to see if the insoles…

This phase 3 trial tests whether an extended-release (once-daily) form of pregabalin works as well as the standard immediate-release (twice-daily) form for relieving nerve pain caused by diabetic peripheral neuropathy or postherpetic neuralgia. About 348 adults aged 18 to 75 with…

This study investigates whether low-frequency pulsed electromagnetic field (PEMF) therapy can improve vibration perception and protective sensation in people with diabetic foot ulcers. Forty-two participants with type 2 diabetes and Wagner grade 1 ulcers will receive either real …

This study tests whether adding nerve gliding exercises (neural mobilization) to standard balance training can reduce pain, improve balance, and boost quality of life in people with diabetic neuropathy. Thirty-two adults aged 50-75 with type 2 diabetes and nerve pain will be spli…