Could a common diabetes pill protect your heart?

NCT ID NCT07614230

First seen Jun 02, 2026

Summary

This study tests whether dapagliflozin, a diabetes medication, can slow or reverse plaque buildup in the heart arteries of people with type 2 diabetes. About 144 adults with stable heart disease will take either the drug plus standard care or standard care alone for 18 months. Researchers will use CT scans to measure changes in plaque and inflammation.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The First Medical Center of Chinese PLA General Hospital

    RECRUITING

    Beijing, Beijing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Sixth Medical Center of Chinese PLA General Hospital

    RECRUITING

    Beijing, Beijing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Dapagliflozin

What this could lead to

If successful, this could show that dapagliflozin helps slow or stop plaque buildup in heart arteries, reducing heart attack risk in people with type 2 diabetes.

What could go wrong

This is a relatively small, early-phase trial (144 participants) testing a secondary effect of an existing drug. The results may not confirm benefit, and side effects like dehydration or infections are possible.

Conditions

The condition(s) this trial relates to.

atherosclerosis coronary artery disorder type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.