New weekly shot could help millions shed pounds and control diabetes

NCT ID NCT07284901

Recruiting now Disease control Sponsor: Kailera Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 3 trial tests a new drug called KAI-9531, given as a weekly injection, in 1700 adults who are overweight or obese and have type 2 diabetes. The study compares KAI-9531 to a placebo to see if it leads to greater weight loss and better blood sugar control over 76 weeks. Participants must have tried and failed to lose weight before.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

KAI-9531

What this could lead to

If successful, this could offer a new once-weekly injection to help people with obesity and diabetes lose weight and improve blood sugar control.

What could go wrong

This is a large Phase 3 trial, but the drug is still experimental. It may not prove superior to placebo, and side effects are possible. Results may not apply to everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus Obesity obesity disorder Overweight type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY WITH DIABETES OVERWEIGHT WITH DIABETES

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Kailera Clinical Site
RECRUITING

Cullman, Alabama, 35055, United States
Kailera Clinical Site
RECRUITING

Phoenix, Arizona, 85012, United States
Kailera Clinical Site
RECRUITING

Sun City, Arizona, 85351, United States
Kailera Clinical Site
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Little Rock, Arkansas, 72205, United States
Kailera Clinical Site
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Escondido, California, 92025, United States
Kailera Clinical Site
RECRUITING

Northridge, California, 91325, United States
Kailera Clinical Site
RECRUITING

Oceanside, California, 92058, United States
Kailera Clinical Site
RECRUITING

Toluca Lake, California, 91602, United States
Kailera Clinical Site
RECRUITING

Stamford, Connecticut, 06905, United States
Kailera Clinical Site
RECRUITING

Jupiter, Florida, 33458, United States
Kailera Clinical Site
RECRUITING

Orange City, Florida, 32763, United States
Kailera Clinical Site
RECRUITING

Lilburn, Georgia, 30047, United States
Kailera Clinical Site
RECRUITING

Skokie, Illinois, 60077, United States
Kailera Clinical Site
ACTIVE_NOT_RECRUITING

Springfield, Illinois, 62702, United States
Kailera Clinical Site
RECRUITING

Newton, Kansas, 67114, United States
Kailera Clinical Site
RECRUITING

Shreveport, Louisiana, 71105, United States
Kailera Clinical Site
RECRUITING

Columbia, Maryland, 21045, United States
Kailera Clinical Site
RECRUITING

Farmington Hills, Michigan, 48334, United States
Kailera Clinical Site
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Missoula, Montana, 59804, United States
Kailera Clinical Site
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Lincoln, Nebraska, 68516, United States
Kailera Clinical Site
RECRUITING

Las Vegas, Nevada, 89148, United States
Kailera Clinical Site
RECRUITING

Albany, New York, 12203, United States
Kailera Clinical Site
RECRUITING

Laurelton, New York, 11413, United States
Kailera Clinical Site
RECRUITING

Greensboro, North Carolina, 27405, United States
Kailera Clinical Site
RECRUITING

Morehead City, North Carolina, 28557, United States
Kailera Clinical Site
RECRUITING

Chickasha, Oklahoma, 73018, United States
Kailera Clinical Site
RECRUITING

Spartanburg, South Carolina, 29303, United States
Kailera Clinical Site
ACTIVE_NOT_RECRUITING

Chattanooga, Tennessee, 37405, United States
Kailera Clinical Site
RECRUITING

Amarillo, Texas, 79124, United States
Kailera Clinical Site
RECRUITING

Brownsville, Texas, 78526, United States
Kailera Clinical Site
RECRUITING

DeSoto, Texas, 75115, United States
Kailera Clinical Site
RECRUITING

Tomball, Texas, 77375, United States
Kailera Clinical Site
RECRUITING

Salt Lake City, Utah, 84117, United States
Kailera Clinical Site
RECRUITING

Manassas, Virginia, 20110, United States
Kailera Clinical Site
RECRUITING

Richmond, Virginia, 23236, United States
Kailera Clinical Site
RECRUITING

San Nicolás de los Arroyos, Buenos Aires, 2900, Argentina
Kailera Clinical Site
RECRUITING

Buenos Aires, Buenos Aires F.D., 1060, Argentina
Kailera Clinical Site
RECRUITING

Rosario, Sante Fe, 2000, Argentina
Kailera Clinical Site
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CABA, 1061, Argentina
Kailera Clinical Site
RECRUITING

Bruce, Australian Capital Territory, 2617, Australia
Kailera Clinical Site
RECRUITING

Blacktown, New South Wales, 2148, Australia
Kailera Clinical Site
RECRUITING

Kanwal, New South Wales, 2259, Australia
Kailera Clinical Site
RECRUITING

Leichhardt, New South Wales, 2040, Australia
Kailera Clinical Site
RECRUITING

Sydney, New South Wales, 2100, Australia
Kailera Clinical Site
RECRUITING

Sydney, New South Wales, 2228, Australia
Kailera Clinical Site
RECRUITING

Wollongong, New South Wales, 2500, Australia
Kailera Clinical Site
RECRUITING

Herston, Queensland, 4006, Australia
Kailera Clinical Site
RECRUITING

Camberwell, Victoria, 3124, Australia
Kailera Clinical Site
RECRUITING

Melbourne, Victoria, 3025, Australia
Kailera Clinical Site
RECRUITING

South Brisbane, 4101, Australia
Kailera Clinical Site
RECRUITING

Grafton, Auckland, 1010, New Zealand
Kailera Clinical Site
RECRUITING

New Lynn, Auckland, 0610, New Zealand
Kailera Clinical Site
RECRUITING

Silverdale, Auckland, 0932, New Zealand
Kailera Clinical Site
RECRUITING

Takapuna, Auckland, 0622, New Zealand
Kailera Clinical Site
RECRUITING

Nawton, Hamilton, 3200, New Zealand
Kailera Clinical Site
RECRUITING

Auckland, 1023, New Zealand
Kailera Clinical Site
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Hastings, 4120, New Zealand
Kailera Clinical Site
RECRUITING

Nelson, 7011, New Zealand