Eating disorder

This phase 2 trial tests whether tirzepatide, a drug used for diabetes and weight loss, can reduce binge-eating episodes and help with weight loss in adults with obesity and binge-eating disorder. About 105 participants will receive tirzepatide, a placebo, or the existing drug li…

This trial tests whether deep brain stimulation—implanting electrodes in specific brain areas—can help people with severe, treatment-resistant mental disorders like OCD, schizophrenia, depression, anorexia, gambling addiction, and autism. The study involves 18 participants and me…

This study tests whether adding smartphone-based self-monitoring and micro-interventions to standard behavioral therapy helps people with bulimia nervosa or binge eating disorder. Participants will use an app to track their eating and practice therapeutic skills, with some receiv…

This study tests whether psilocybin, a psychedelic substance, given with psychological support is safe and helps reduce symptoms of anorexia nervosa in young adults aged 16 to 35. Participants receive two doses of psilocybin (25 mg) four weeks apart, plus therapy before, during, …

This study compares two weight-loss strategies: GLP-1 medications (like semaglutide or tirzepatide) versus a structured diet and exercise program. Adults with a BMI of 27.5 or higher are followed for three months to see which approach better improves heart and metabolic markers, …

This Phase 3 trial is testing whether solriamfetol, a drug already approved for sleep disorders, can reduce binge eating episodes in adults with binge eating disorder. About 450 participants will receive either solriamfetol or a placebo daily for 12 weeks. The main goal is to see…

This study tests three different intensities of cognitive behavioral therapy (CBT) against standard treatment to see which best reduces binge eating episodes in adults with binge eating disorder. Over 21 weeks, participants receive individual therapy sessions ranging from low to …

This study compares two psychological treatments for adolescents aged 12-18 with anorexia nervosa: a new approach called Interoceptive Exposure Therapy (IE) versus standard Family Based Therapy (FBT). IE helps teens face food-related fears by pairing feared foods with positive ex…

This early-stage study tests whether MDMA (the active ingredient in ecstasy) combined with talk therapy can help people with bulimia nervosa. Forty adults will be assigned to one of three groups: MDMA with general therapy, MDMA with bulimia-specific therapy, or standard treatment…

This study aims to find out which parts of a relapse prevention treatment work best for people with anorexia nervosa after they leave the hospital. About 60 adults who have regained a healthy weight will take part. Researchers will track weight changes, eating habits, and motivat…

This study is testing whether a skin patch that delivers estrogen can help improve bone density in adult women with anorexia nervosa who have low bone mass. Participants will be randomly assigned to receive either the estrogen patch or a placebo patch for 18 months. The main goal…

This study is testing a type of family-based therapy for teenage girls with anorexia. The therapy involves the whole family in treatment. Researchers want to see if it helps girls recover and no longer meet the criteria for an eating disorder. Sixty participants are being recruit…

This study looks at whether a therapeutic ketogenic diet (a high-fat, low-carb diet) can normalize brain metabolism and reduce lingering eating disorder symptoms in people who have recovered from anorexia nervosa. About 90 participants, including healthy controls, will undergo br…

This study tests a 'Metabolic Diet' designed to help women with anorexia nervosa maintain a healthy weight after they have regained weight. Twenty adult women who recently reached a normal weight will follow the diet with a dietitian's help for 10 weeks. Researchers will monitor …

This study tests whether early, intensive day hospital treatment—with family involvement and multidisciplinary care—can improve outcomes for adolescents with anorexia nervosa compared to standard outpatient care. About 164 teens aged 12-18 with recent-onset anorexia will be enrol…

This study looks at whether children aged 8-13 with early onset anorexia nervosa can be treated with a shorter hospital stay followed by day treatment (going home at night) instead of staying in the hospital full-time. The goal is to see if this approach works just as well for we…

This study looks at whether adding GLP-1 weight-loss drugs to cognitive behavioral therapy helps adults with severe obesity and binge eating disorder. About 80 participants will either take a GLP-1 drug or not, while both groups attend therapy sessions. Researchers will track cha…

This study tests whether a special blend of amino acids (protein building blocks) can help people with anorexia nervosa gain lean muscle mass during hospital treatment. 92 patients will receive either the supplement or a placebo, alongside standard therapy. The main goal is to se…

This study is testing whether two questionnaires (SCOFF-F and EDE-Q) can accurately detect eating disorders in pregnant women, separating them from normal pregnancy-related eating concerns. Researchers will compare answers from 50 pregnant women with and without diagnosed eating …

This study is testing whether a simple dental checklist can help identify people who might have an eating disorder. Researchers will check the mouths of 461 adults aged 18 to 40 for signs like tooth erosion or other oral issues. They will then compare the checklist results with s…

Researchers at Duke University are testing FlexED, a smartphone-based gamified intervention designed to help young women aged 18 to 25 who are at risk for eating disorders. The program uses interactive exercises and games based on Acceptance and Commitment Therapy to teach psycho…

This trial tests a school-based program called the Young Athlete Body Project, designed for adolescent athletes in Norway. The program includes digital lessons and group workshops that challenge unhealthy appearance ideals and build resistance to social pressures. Researchers wil…

This trial tests whether a single online session can help prevent eating disorders in young adults at risk. Participants will complete a screening survey and then receive a brief intervention that teaches about habits and how to change them. The study aims to see if this approach…

This study tests a digital chatbot program designed to prevent eating disorders in adolescents aged 13 to 19 who are at risk. Participants use the chatbot daily for three months to complete modules based on cognitive-behavioral therapy, focusing on body image and eating behaviors…

This study tests a 6-week group program called PrevED MR that uses mixed reality and virtual reality to teach emotion regulation skills to teens and young adults at risk for eating disorders. The program includes 12 sessions combining therapy exercises with immersive experiences.…

This study tests a 6-month lifestyle program designed to prevent obesity and eating disorders in transgender and gender-diverse adolescents aged 10-14. Participants attend monthly group sessions and receive weekly supportive messages. The goal is to improve quality of life and bo…

This study tests whether an eHealth app that coaches parents can help lower the energy balance in children aged 2-6 who are already above the 97th BMI percentile. About 148 families will be randomly assigned to use the app or receive standard care. The goal is to see if the app c…

This study tests whether adding a mobile app and digital monitoring to standard group therapy can better prevent suicide risk in women with eating disorders. Researchers will compare two groups of 150 women aged 18-65 who have recently had suicidal thoughts or attempts. One group…

This study is testing a program called the Body Project, designed to prevent eating disorders in girls and young women aged 15 to 22 in Nova Scotia. Participants attend group sessions led by peer mentors, either in person or online, and fill out questionnaires before and after. T…

This study tests whether giving lactase enzyme drops with formula milk can prevent feeding intolerance in very premature infants (≤32 weeks). 120 babies will receive either lactase or placebo for 14 days. Researchers will track vomiting, stomach swelling, and leftover milk in the…

This study tests an online program called PRETA, designed to reduce risk factors for eating disorders in pre-adolescents (ages 10-12). The program includes interactive sessions for students, plus materials for parents and teachers. About 1,068 students from schools in Spain will …

This study tests whether a type of talk therapy called Acceptance and Commitment Therapy (ACT) can help people with type 1 diabetes who also have eating disorders. Participants will be randomly assigned to ACT, supportive diabetes counseling, or a waitlist. The goal is to see if …

This study tests whether adding a peer coach or parent coach to standard eating disorder therapy helps teens aged 12-18 recover faster. 70 participants will receive 12 weeks of therapy plus either a parent coach with patient education materials or patient coaching with parent edu…

This study tests a non-invasive device that stimulates the vagus nerve before meals in teens and young adults (ages 14-22) with anorexia or similar eating disorders. Over 4 weeks, participants receive either real or sham stimulation to see if it boosts meal satisfaction, calorie …

This trial tests FlexED, a digital game-like intervention for young women aged 15–25 with eating disorders. Over seven 20-minute sessions on a mobile phone, users follow an avatar through a story and complete interactive exercises based on Acceptance and Commitment Therapy (ACT).…

This study at the University of Pennsylvania is testing whether personalized brain stimulation can reduce negative emotions in people with depression and anxiety. Researchers will use brain scans to map each participant's negative emotion patterns, then apply different types of t…

This study tests a digital program called FlexED that uses games and exercises to help young women and girls (ages 15-25) who struggle with body image and eating disorder symptoms. Participants are randomly assigned to either the FlexED program or online education modules. The go…

This trial tests whether a 12-week online program that blends family-based treatment with dialectical behavior therapy can reduce the heavy burden often felt by caregivers of teenagers with anorexia nervosa. Caregivers are randomly assigned to either this combined program or a ge…

This study tests whether a nasal spray containing oxytocin (a natural hormone) can help adults with binge-eating disorder eat less often in binges. About 60 adults will receive either the oxytocin spray or a placebo for 8 weeks. Researchers will track changes in binge frequency a…

This trial explores whether a non-invasive device that delivers mild electrical stimulation to the head can help reduce anxiety before meals in adults hospitalized for eating disorders. Participants will use the Alpha-Stim AID device for 20-minute sessions before breakfast, lunch…

This study tests a remote behavioral therapy called PAT-AN for adults recovering from anorexia. The therapy focuses on enhancing the brain's reward response to non-food experiences, like hobbies or socializing, to reduce reliance on weight-loss behaviors. Participants will receiv…

This study tests whether metreleptin, a synthetic version of the hormone leptin, can help people with anorexia nervosa feel less depressed and gain weight. About 50 hospitalized patients will receive either metreleptin or a placebo, and researchers will track mood, weight, and br…

This clinical trial tests whether a 15-week parent-led nutrition program called Exploradores de Sabores can help children aged 4 to 11 with autism spectrum disorder eat a more varied diet and improve their nutritional status. Caregivers attend weekly group sessions with a dietiti…

This study will test a smartphone chatbot called Wysa that delivers cognitive-behavioral therapy-based self-help for adults with eating disorders. 800 participants will use the chatbot daily for eight weeks. The goal is to see if this digital tool can reduce eating disorder sympt…

This study tests two smartphone-based programs for adults with binge eating disorders. One program uses heart rate feedback and breathing exercises, while the other uses guided body scans to help people connect with internal sensations like hunger. The goal is to reduce binge eat…

This study tests whether adding dramatherapy—using role play, improvisation, and creative exercises—to a standard exercise program improves quality of life for adults with obesity and eating disorders. Participants are in medical or bariatric care and will be randomly assigned to…

This study tests a mobile app that delivers an 8-week cognitive-behavioral therapy program for adults with Avoidant/Restrictive Food Intake Disorder (ARFID). ARFID is a serious eating disorder that makes it hard to eat enough or try new foods, and many people cannot access treatm…

This study tests whether a text message program that helps people reduce 'safety behaviors' (like checking mirrors or seeking reassurance) can lessen appearance anxiety, body dysmorphic symptoms, and related eating or social anxiety issues. About 300 adults with high appearance c…

This study tests whether a support group for siblings (ages 2-18) of teenagers with anorexia nervosa is acceptable and helpful. About 24 siblings will attend group sessions and fill out questionnaires about their experience and quality of life. The goal is to see if this kind of …

This study explores whether teaching people emotion regulation skills tailored to their individual needs works better than a one-size-fits-all approach. Researchers will enroll 390 adults with emotional difficulties, such as depression, anxiety, or PTSD, and assign them to practi…

This study tests a mobile app designed to help adults with eating disorders stay motivated and ready for treatment while they are on a waitlist. Participants will either use the app for four weeks or continue with standard waitlist care. The goal is to see if the app can prevent …

This study tests a virtual reality program for children under 14 with anorexia nervosa. Kids will view an avatar of themselves in a mirror, gradually increasing in size to a healthy weight, to reduce anxiety about gaining weight. The goal is to improve eating habits and body imag…

This study tests whether a virtual therapy guided by parents can help teens with anorexia nervosa while reducing long wait times for treatment. About 90 families will take part, with parents leading sessions using a structured program. The goal is to see if this approach eases sy…

This study tests whether AI-generated audio stories can help people with anxiety and fear of failure. Forty adults will listen to personalized scenarios based on childhood memories of criticism, with one version including a therapeutic twist where a supportive figure steps in. Th…

This study tests two types of social therapy for young adults (ages 18-30) with eating disorders or anxiety. One group gets educational sessions about brain function and social processing; the other adds interactive art tasks done in teams. Researchers will track changes in eatin…

This study tests whether combining mindfulness meditation with real-time brain scan feedback can help teens with depression. Researchers will train 90 adolescents aged 13-18 to control brain circuits linked to rumination (repetitive negative thinking). The goal is to see if this …

This study tests whether adding a digital mindfulness program to usual care helps adults aged 18-65 recover from emotional disorders like depression, anxiety, OCD, PTSD, and eating disorders. Participants attend online group sessions and use a WeChat mini-program for daily exerci…

This study tests a brief online program called COR for adults who struggle with binge eating. The program includes eight weekly sessions that teach skills to manage emotions and reconnect with eating in a healthy way. Researchers want to see if people find the program helpful and…

This study tests a virtual reality (VR) headset that uses circadian reset technology to improve sleep and reduce binge eating in 40 adults with binge eating disorder. Participants use the headset for 10 minutes twice daily for one month. Researchers will compare changes in binge …

This study looks at 40 children who get most of their nutrition through a feeding tube. Researchers want to see if a thicker blenderized tube feed helps reduce stomach symptoms like nausea and bloating compared to a thinner one. Each child will try both types over 16 weeks, and p…

This study is testing an AI-powered chatbot called Exp-ED that guides teens and young adults through exposure therapy exercises to reduce anxiety about weight gain. Twenty participants in a partial hospitalization program for eating disorders will use the app for six weeks. Resea…

This pilot study is testing a new type of talk therapy, called Exposure Therapy for Anorexia (Exp-AN), delivered virtually to 16 teenagers aged 14-17 with anorexia nervosa. The therapy helps teens identify and face their fears about gaining weight through real-life and mental exe…

This study is testing a type of talk therapy called Emotion Regulation Therapy (ERT) delivered over video for people in New York who struggle with worry, overthinking, or being hard on themselves. The goal is to see if the therapy helps people better manage their emotions and fee…

This study tests a 6-week virtual program called the Diabetes Body Project 2, designed to prevent eating disorders in women aged 18-40 with type 2 diabetes. The program includes weekly group sessions and home exercises to improve body image and reduce disordered eating. Researche…

This study is testing whether a 6-session online program called Metacognitive Training for Eating Disorders (MCT-ED) is practical and acceptable for teenagers aged 13-19 with anorexia or atypical anorexia. The program helps teens recognize and change unhelpful thinking patterns r…

This study tests whether psilocybin, a psychedelic substance, can help young adults aged 18-25 with hard-to-treat anorexia nervosa. Participants receive two doses of psilocybin along with therapy sessions, and family members are also involved. The goal is to see if psilocybin inc…

This study tests whether a new 5-day outpatient therapy called Temperament Based Therapy with Support (TBT-S) can help reduce eating disorder symptoms in adults with anorexia nervosa. 120 participants will either receive TBT-S plus their usual care or usual care alone. Researcher…

This study tests whether a team of a psychologist, speech therapist, and motor therapist can help children aged 2-7 with neurodevelopmental disorders eat more foods and have fewer mealtime struggles. 24 children will be split into two groups: one gets the team therapy, the other …

This pilot study tests whether a gentle electrical current applied to the back of the brain (cerebellum) can improve social behaviors and mental flexibility in 15 women and girls aged 15-30 with anorexia nervosa. Participants receive two types of stimulation (anodal and cathodal)…

This study tests whether a zinc-containing syrup (Biolizin) can improve eating habits in children aged 6 to 36 months who have poor appetite without a known medical cause. About 110 children will take the supplement or receive standard care for 42 days. Researchers will measure c…

This study tests a noninvasive brain-training technique called neurofeedback in 30 women with bulimia nervosa. Using a wearable headband that measures brain activity, participants receive real-time feedback while eating to improve self-control. The goal is to see if this training…

This study tests a mobile app called BEST-U that helps university students reduce binge eating. About 74 students with binge-eating disorder or bulimia will use the app or a comparison therapy. The goal is to see if the app makes it easier for students to get effective help witho…

This study tests a mobile app called FoodTraining that trains people to resist food cues. About 113 adults with obesity, bulimia, or binge-eating disorder will use the app for 4 weeks alongside their usual treatment. Researchers will measure changes in emotional eating and uncont…

This study compares two types of talk therapy for teenagers with eating disorders: enhanced cognitive-behavior therapy and family-based treatment. About 200 adolescents will be randomly assigned to one of the two therapies. The goal is to see if cognitive-behavior therapy works a…

This study tests whether a personalized digital treatment program is practical and helpful for adolescents aged 15-18 with certain eating disorders. Over 10 weeks, participants use an online program with weekly therapist contact and complete questionnaires about their symptoms an…

This study tests a culturally and language-adapted internet-based cognitive behavioral therapy (i-CBT) for Farsi/Dari-speaking youth migrants and refugees aged 15-29. The goal is to reduce symptoms of common mental health problems like anxiety, depression, and stress. Participant…

This study tests whether a 16-session digital program that combines mindfulness with cognitive-behavioral therapy (CBT) is acceptable and practical for adults with binge eating disorder. Forty participants will be randomly assigned to the combined program or a simpler self-monito…

This study tests a new way to treat eating disorders by personalizing therapy based on each person's most troubling symptoms. Researchers use smartphone surveys to map individual symptom patterns, then match participants to specific therapy modules. The goal is to see if this tai…

This study tests a type of talking therapy called exposure-based cognitive behavioral therapy (CBT) for adults who have both functional dyspepsia (a stomach condition causing pain and fullness) and avoidant/restrictive food intake disorder (ARFID), leading to weight loss. Fifty p…

This pilot study tests whether artificial intelligence can create personalized therapy scripts to help adults reframe painful memories of childhood criticism. Eighty participants with anxiety will listen to AI-generated audio scenarios based on their own memories. Half will recei…

This study compares two ways of weighing teens and young adults with eating disorders like anorexia: open weighing (where they see their weight and talk about fears) and blind weighing (where they don't see it). The goal is to see if open weighing reduces anxiety about weight gai…

This study tests whether two types of non-invasive brain stimulation—rTMS and tDCS—can improve symptoms of anorexia nervosa. Seventy participants in an inpatient setting will receive either active or sham (placebo) stimulation over 8 weeks. Researchers will measure changes in eat…

This study tests whether a therapeutic ketogenic diet can reduce troubling eating disorder symptoms like the drive to restrict, binge, or purge, and body dissatisfaction. It includes adults with anorexia nervosa (both weight-recovered and underweight) and bulimia nervosa. Over 14…

This study follows 1,500 children ages 8 to 17 over several years to learn how genes, sleep, mood, and environment affect eating behavior and overall health. Participants wear wrist monitors, answer smartphone surveys, and provide samples like blood and stool. The goal is to iden…

This study explores how the brain and stomach communicate in people with functional dyspepsia (a condition causing stomach pain and fullness without a clear cause) and anorexia nervosa. Participants will eat a pineapple pudding snack while undergoing brain scans (fMRI) before and…

This observational study looks at whether the bacteria in the gut are linked to eating disorders in children and teenagers. Researchers will compare the gut microbiome, diet, and psychological factors between young patients with eating disorders and healthy peers. They will also …

This study looks at how people with binge eating disorder record their episodes using two different diary formats: a traditional paper diary and an electronic diary on a smartphone. Researchers want to see if both formats collect the same information and which one people find eas…

This study is testing a smartphone app that uses brief surveys and phone sensor data to detect when someone with an eating disorder might be at higher risk for behaviors like binge eating, restricting food, or purging. The app then delivers short video lessons on coping skills. T…

This study uses a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) to explore how it changes food choices and brain activity in people with anorexia nervosa. Researchers will give a single session of rTMS to 72 women aged 18-30 w…

This study aims to collect genetic data and detailed symptom histories from 20,000 people with or without eating disorders like anorexia, bulimia, binge-eating disorder, and ARFID. Participants complete questionnaires and provide a saliva sample for DNA analysis. The goal is to i…

This study investigates whether older adults with age-related hearing loss (presbycusis) can still hear and enjoy the sound of a crunchy biscuit while eating. Researchers will compare a crunchy biscuit with a soft one in 100 seniors aged 65 and older, asking them if they hear the…

This study looks at how a mindfulness app might help teenagers (ages 13-18) who tend to ruminate—getting stuck in repetitive negative thoughts. Participants will be randomly assigned to use the app or a control activity, and will have brain scans and cognitive tests before and af…

This study looks at 100 adults with severe obesity to see if the type of weight-loss surgery—sleeve gastrectomy or gastric bypass—changes binge eating, depression, and anxiety differently. Participants fill out questionnaires before surgery and for 12 months after. The goal is to…

This study takes a small blood sample from women with severe anorexia and healthy women, then turns those cells into brain-like neurons in a dish. Researchers will test how these neurons respond to hunger and fullness hormones. The goal is to uncover cellular differences that mig…

This study uses brain scans (fMRI) and computer tasks to understand how women with anorexia or bulimia nervosa learn to avoid certain situations. Researchers will compare brain activity in 78 women—26 with anorexia, 26 with bulimia, and 26 healthy controls—to see if avoidance lea…

This study uses brain scans (fMRI) to investigate how the brain processes 'liking', 'wanting', and learning in women with anorexia or bulimia. Researchers will compare 189 women with eating disorders to 63 healthy women, using computer tasks and a test meal. The goal is to unders…

This study looks at how nomophobia—the fear of being without your smartphone—relates to stress, body image, and food addiction in university students aged 18 to 30. Researchers will use questionnaires and body measurements to find connections. The goal is to better understand the…

This observational study looks at how people with different eating disorders—like ARFID, anorexia, and bulimia—think and process information. Researchers will use questionnaires and computer tasks to measure traits like cognitive flexibility and body perception. The goal is to be…

This study looks at specific fat molecules (sphingolipids) in the blood of women with anorexia nervosa. Researchers will compare these molecules between patients and healthy women, and see how they relate to hormone levels and mood. The goal is to find patterns that could lead to…

This study compares how people with anorexia nervosa, those who have recovered, and healthy controls metabolize food after eating a breakfast sandwich. Researchers aim to understand genetic and biochemical factors that influence food metabolism and anxiety around eating. The goal…

This study looks at how certain thinking patterns, called metacognitive beliefs, relate to eating disorders in teenagers. Researchers will compare 72 girls aged 12-17 who have an eating disorder with a similar group of girls without one. The goal is to understand if these thought…

This study will measure body composition, resting metabolism, and physical activity in 60 teenage girls with and without anorexia nervosa. Researchers want to see if simple body measurements can help define how advanced the disease is and guide recovery. The goal is to improve mo…

This study looks at young women with anorexia nervosa to see if changes in a gene related to appetite and wakefulness (the orexin gene) are linked to how severe their eating disorder is, whether they have depression, and how well they sleep. Researchers will compare these women t…

This study looks at how certain psychiatric drugs may change heart rhythms in children and teens. Researchers will track 100 young patients with eating disorders, mood disorders, or psychosis who are starting a new psychiatric medication. They will perform ECGs at the start and a…

This study investigates whether certain autoantibodies (anti-HIF1a) are more common in people with anorexia nervosa who also have liver damage. Researchers will compare 100 anorexia patients (with and without liver issues) to 150 control participants, including healthy individual…

This study tests whether combining a one-time session of brain stimulation (rTMS or electrical scalp stimulation) with emotion regulation training helps people with mood, anxiety, or related disorders better control their emotions. 240 participants will learn either cognitive res…

This study uses two special scanners (HR-pQCT and pQCT) to take detailed pictures of bone and muscle in 1,000 people with conditions that raise the risk of bone loss, like osteoporosis, arthritis, or kidney disease. The goal is to see if these scanners can spot tiny changes in bo…

This study looks at how eating changes brain activity related to self-control in women with bulimia nervosa. Researchers will use MRI scans to compare brain responses after fasting versus after a meal. The goal is to understand why control breaks down, leading to cycles of bingei…

This study tests whether offering three early phone calls and five online support group sessions to adults with eating disorders (like anorexia or bulimia) during their wait for specialized care can reduce the number of people who drop out before starting treatment. About 215 adu…

This study explores why some teenagers with anorexia urinate excessively when they start eating again in the hospital. Researchers think a hormone called secretin might be involved. They will compare secretin levels in teens who urinate a lot versus those who don't, using one ext…

This study follows 140 people who were first hospitalized for early-onset anorexia nervosa between 2016 and 2021. Researchers will check their physical and mental health 4 to 9 years later using questionnaires and medical records. The goal is to understand long-term recovery and …

This study explores whether fecal microbiome transplants (FMT) can improve gut health, thinking, and mood in people with anorexia nervosa. Twenty participants with restrictive-type anorexia will receive FMT capsules. The main goal is to see if the procedure is feasible and tolera…

This research study collects health information from 10,000 people with brain inflammation conditions like Long COVID, ME/CFS, and autoimmune diseases. Participants use a smartphone app to share symptoms, health history, and wearable data. The goal is to find disease subtypes and…

This study surveys 269 healthcare professionals in Alsace, France, including psychiatrists, midwives, and general practitioners, to understand their knowledge and practices around eating disorders during pregnancy and the postpartum period. The goal is to identify gaps in care an…

This study looks at whether newer automated insulin delivery systems help people with type 1 diabetes have healthier eating behaviors. Researchers will survey over 100 youth and adults across Canada about their eating habits and blood sugar control. The goal is to understand if t…

This study investigates how the brain processes anticipation of rewards in people with bulimia nervosa. Researchers will use brain scans (fMRI) and daily-life surveys to compare 100 participants—those with bulimia and healthy controls. The goal is to identify neural and psycholog…

This pilot study aims to see how common Barrett's esophagus is in people with eating disorders who have been purging (vomiting or ruminating) for at least 5 years. Researchers will use a simple, non-endoscopic device called EsoGuard to collect cell samples from the esophagus. The…

This study looks at how a temporary loss of control changes the way people with anorexia process information. Researchers think that focusing on small details (analytical thinking) might be a way to feel more in control. They will measure reaction times before and after a control…

This study aims to identify subgroups of people with diabetes who share similar patterns between their blood sugar levels and mental health. By using smartphone surveys and continuous glucose monitors, researchers will create 'digital twins'—virtual models that can predict how me…

This study tests whether functional MRI (fMRI) brain scans can detect changes caused by a single dose of naltrexone in adolescents aged 13-21 with eating disorders involving binge eating or purging. Participants receive both naltrexone and a placebo in random order, two weeks apa…

This study looks at the link between gut bacteria and mental health symptoms like anxiety and depression in people with anorexia nervosa. Researchers will compare 120 participants (patients with severe anorexia and healthy volunteers) to see if changes in gut bacteria, intestinal…

This study looks at the connection between gut bacteria, body fat changes, and fear of gaining weight in people with anorexia nervosa. Researchers will collect stool and blood samples from 60 women admitted for refeeding to analyze their gut microbiome. The goal is to find biomar…

This study looks at whether people with obesity who also have binge eating or food addiction experience tastes differently than those without these behaviors. Researchers will measure sweet and salty taste thresholds in 300 participants and compare groups. The goal is to understa…

This study takes gut bacteria from women with eating disorders (like anorexia or bulimia) and gives them to mice to see if the mice gain or lose weight differently. The goal is to understand if an unhealthy gut microbiome can influence body weight and eating behavior. It's a basi…

This study explores whether a sham (fake) neurofeedback system in virtual reality can change brain activity related to attention. About 35 adults with rumination or chronic pain will undergo EEG recordings while experiencing positive, negative, or no feedback. The goal is to see …

This study explores whether floating in a warm, saltwater tank (floatation-REST) while practicing mindfulness can reduce body image dissatisfaction in people with anorexia nervosa. 102 participants will be randomly assigned to either the floatation therapy or a control group watc…

This study follows about 185 patients with anorexia or bulimia during inpatient weight rehabilitation to see how their stomach and gut symptoms change over time. Researchers will compare three diet types—flexitarian, vegetarian, and vegan—to find out which is linked to fewer dige…

This study follows 125 women with anorexia nervosa during and after intensive inpatient treatment to understand why relapse happens. Researchers will use brain imaging, genetic tests, and behavioral tasks to look for patterns. The goal is to find factors that help predict who sta…

This study looks at how multifamily therapy—where several families meet together—helps teenagers with anorexia nervosa. Researchers will interview teens, parents, and siblings who took part in the therapy at a Paris hospital. The goal is to understand how the therapy affects eati…

This study uses interviews to learn how adolescents with anorexia nervosa, their parents, and healthcare professionals experience psychotropic drugs. Researchers will talk to 90 participants to uncover their thoughts and feelings. The goal is to better understand the personal imp…

This study interviews 30 competitive athletes to learn what they believe causes and triggers eating disorders in sports. Half of the participants have had an eating disorder, and half have not. The goal is to compare their experiences and gather ideas on how to better prevent the…