Hormone clue to refeeding urine problem in anorexia teens
NCT ID NCT05235867
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study explores why some teenagers with anorexia urinate excessively when they start eating again in the hospital. Researchers think a hormone called secretin might be involved. They will compare secretin levels in teens who urinate a lot versus those who don't, using one extra blood and urine sample during their stay.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 10 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2022
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adolescents with restrictive-type anorexia hospitalized for medical nutritional stabilization.
- Ages
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13 to 24 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Group 1: * male and female patients * age 13-24 years * diagnosis of restrictive-type anorexia nervosa * hospitalization for nutritional support * \>4 cc/kg/day of urine output (a.k.a. "fluid dumpers"; n=5) * Group 2: * male and female patients * age 13-24 years * diagnosis of restrictive-type anorexia nervosa * hospitalization for nutritional support * \<2 cc/kg/d of urine output (a.k.a. "non-dumpers"; n=5) Exclusion Criteria: * 5150 hold * Anti-depressant, anti-psychotic, or anticonvulsant medications * Previous hospitalization within the past 6 months * Underlying metabolic disorder not related to anorexia nervosa (including chronic kidney disease, renal tubular disorders, and underlying endocrine disorders) * Pregnancy * NG or G-tube feeds after day 2 of hospitalization * \> 10% of nutritional needs from supplemental feeds
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of California, Los Angeles (UCLA)
RECRUITINGLos Angeles, California, 90095, United States
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