Simple enzyme drops could help tiny babies tolerate feeds

NCT ID NCT07088302

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving lactase enzyme drops with formula milk can prevent feeding intolerance in very premature infants (≤32 weeks). 120 babies will receive either lactase or placebo for 14 days. Researchers will track vomiting, stomach swelling, and leftover milk in the stomach to see if the enzyme helps.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
lactase enzyme drops
What this could lead to
If it works, this could offer a simple way to prevent feeding problems in premature babies, reducing time in the NICU.
What could go wrong
This is a small, early-stage trial with only 120 infants. The effect may be small or not work at all, and results may not apply to all preterm babies.

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Conditions

The condition(s) this trial relates to.

congenital lactase deficiency eating disorder Feeding and Eating Disorders Premature Birth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Marwa Mohamed Farag

    RECRUITING

    Alexandria, 0325, Egypt

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