Could a daily vitamin pill fortify breast milk for the tiniest babies?

NCT ID NCT07736768

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

Preterm infants are born with low vitamin A stores and rely on breast milk to meet their needs, putting them at risk for deficiency. This trial tests whether giving mothers of very preterm infants (born before 29 weeks) a daily high-dose vitamin A supplement for four months can increase vitamin A levels in their breast milk. Researchers will measure vitamin A concentrations in milk samples collected at two weeks, two months, and four months after birth to see if this simple approach works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
an oral multivitamin supplement containing 1,300 mcg RAE of vitamin A taken daily
What this could lead to
If it works, this could point toward a simple way to improve the nutritional quality of breast milk for preterm infants, potentially reducing vitamin A deficiency and related health issues.
What could go wrong
This is a small early-stage trial with only 20 participants, so results may not apply broadly. The supplement may not significantly raise vitamin A levels in breast milk, or the effect may vary among mothers.

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Conditions

The condition(s) this trial relates to.

Breast Feeding Premature Birth vitamin A deficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Mississippi Medical Center

    Jackson, Mississippi, 39216, United States

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