Could a leptin shot lift mood and weight in anorexia?

NCT ID NCT06305182

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether metreleptin, a synthetic version of the hormone leptin, can help people with anorexia nervosa feel less depressed and gain weight. About 50 hospitalized patients will receive either metreleptin or a placebo, and researchers will track mood, weight, and brain changes. The goal is to find a new way to make treatment easier and more effective.

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Conditions

The condition(s) this trial relates to.

anorexia nervosa Depression Weight Gain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Eating Disorder Unit, Clinic of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich

    RECRUITING

    Zurich, Canton of Zurich, 8091, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

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