Stanford University

This study tests whether a device called Eyetronic, which delivers mild electrical pulses through the eyes, can help people with glaucoma. Glaucoma damages the optic nerve and can lead to vision loss. The trial will compare the active device to a sham (fake) version in 30 adults …

This early-stage trial tests a personalized cell therapy called KYV-101 for people with progressive forms of multiple sclerosis (MS) that are not responding to standard treatments. The therapy uses a patient's own immune cells, modified to target and destroy certain immune cells …

This study looks at how fat cells work differently in normal-weight people with type 2 diabetes compared to those without diabetes. Researchers will test two drugs, pioglitazone and tirzepatide, to see if they improve insulin resistance and fat storage. About 104 adults aged 30-7…

This study tests whether meals designed for specific ethnic groups (South Asian and Filipino) can help control blood sugar in people with type 2 diabetes. Thirty participants will wear a continuous glucose monitor for a month while eating their usual diet and then specially prepa…

This phase 2 trial is testing a combination of three immune-boosting drugs (relatlimab, nivolumab, and ipilimumab) in 60 people with melanoma that has spread to the brain. The study includes both patients with and without symptoms from their brain tumors. The main goal is to see …

This study looks at whether adding two extra treatments—neuromuscular electrical stimulation (NMES) and blood flow restriction (BFR)—to standard physical therapy can help teens recover better after ACL reconstruction. Forty adolescents who had ACL surgery will be assigned to eith…

This study tests whether counseling plus a muscle relaxant (tizanidine) can help adults who have used opioids for a long time reduce their pain medication after elective surgery. About 375 participants will be randomly assigned to one of three groups: the combo treatment, counsel…

This study tests a combination of the targeted drug tagraxofusp with two chemotherapy drugs (cladribine and cytarabine) in 20 adults whose acute myeloid leukemia (AML) has come back or not responded to prior treatment. The goal is to find the safest dose and see how well the comb…

This early-phase trial tests a cell therapy called Orca-T combined with standard drugs to prevent graft-versus-host disease (GVHD) in 24 adults with advanced blood cancers (like leukemia or MDS) receiving stem cell transplants from partially matched donors. The main goal is to se…

This study tests an adaptive web-based program called Partners Connect for military couples. It aims to reduce drinking in concerned partners and encourage service members to seek help for alcohol use. About 744 couples will participate, comparing the online program to standard w…

This study tests whether adding a special scaffold (Biobridge) to standard lymph node transfer surgery improves arm swelling in people with lymphedema. About 60 adults with stage I-II arm lymphedema will be enrolled. The goal is to help the transplanted lymph node connect better,…

This study tests whether giving radiation therapy before surgery can eliminate ductal carcinoma in situ (DCIS), a very early form of breast cancer, better than surgery alone. About 50 women with small, non-invasive breast spots will be randomly assigned to either standard surgica…

This study compares a shorter course of brachytherapy (3 sessions) to the standard 4-session regimen for locally advanced cervical cancer. About 41 participants will receive either 3 or 4 high-dose radiation treatments based on what is feasible for them. The goal is to see if the…

This early-stage trial tests a new treatment called B7-H3CART, which uses a patient's own immune cells modified to target a protein (B7-H3) found on certain solid tumors. It includes up to 41 children and young adults with relapsed neuroblastoma, sarcoma, or osteosarcoma who have…

This study tests whether injecting micro fragmented fat tissue into the shoulder joint can reduce pain and improve function in people with shoulder osteoarthritis. Half of the 48 participants will receive the fat injection, while the other half get a standard steroid shot. The go…

This early-phase trial tests niclosamide, a drug previously used for tapeworm infections, combined with standard chemotherapy in 16 children whose acute myeloid leukemia (AML) has returned or not responded to treatment. The main goal is to find a safe dose and check for side effe…

This study compares two surgical approaches for Fuchs endothelial dystrophy, a condition that clouds the cornea. One is a full corneal transplant (DMEK), the other is a simpler procedure that removes only the diseased cells (DSO) plus Ripasudil eye drops to help healing. 60 parti…

This Stanford study tests whether the drug pramipexole can help people with depression, and whether brain scans can predict who will respond best. Sixty adults with current depressive symptoms will take pramipexole for 8 weeks, then taper off. The goal is to move toward personali…

This phase 2 trial tests whether a gene therapy gel called BVEC can reduce the return of squamous cell carcinoma (a type of skin cancer) in people with recessive dystrophic epidermolysis bullosa (RDEB), a rare genetic condition that causes fragile, blistering skin. The gel is app…

This large study tests a new way of delivering diabetes care called iPATH, which uses a team of providers and technology to help patients better control their blood sugar. Researchers will enroll about 120,000 adults with type 2 diabetes at 16 community health centers across the …

Stanford University is studying the da Vinci Xi robotic system in 250 children and teens aged 6-21. The goal is to see if the robot is safe and works well for various surgeries like gallbladder removal or lung procedures. Participants must weigh at least 15 kilograms and have not…

This early-stage trial tests whether a new immune cell therapy called GD2 CAR T cells can be safely made and given to children and adults with a rare, aggressive brain tumor called H3K27M-mutant diffuse midline glioma. The study aims to find the right dose and check for side effe…

This study tests whether a nutrition program that provides twice-daily meal delivery for up to 90 days after hospital discharge, plus diet education, can reduce food insecurity in people with type 1 or type 2 diabetes. About 160 hospitalized patients who screen positive for food …

This study uses a blood test to detect tiny amounts of cancer DNA left after standard treatment for early-stage non-small cell lung cancer. People whose blood shows this leftover cancer are at higher risk of the cancer coming back. The study tests whether the drug durvalumab can …

This study tests whether a 5-day course of radiation before surgery is as safe and effective as the standard 25-day course for adults with soft tissue sarcoma. Researchers will track complication rates and whether the cancer comes back. The goal is to make treatment faster and mo…

This study looks at two methods of repairing a key shoulder muscle (subscapularis) during total shoulder replacement. One method uses standard stitches, the other adds a special support called Biobrace. Researchers will use ultrasound and X-rays to see which repair heals better a…

This study tests whether deep transcranial magnetic stimulation (TMS) can help Veterans with alcohol use disorder reduce relapse. About 100 participants will receive TMS targeting brain circuits linked to craving and emotional processing. The goal is to increase alcohol-free days…

This study tests whether bumetanide, a water pill used for high blood pressure, is safe for people with early Alzheimer's. Researchers will give the drug or a placebo to 40 adults with mild memory problems. The goal is to see if it can be tolerated and possibly help with symptoms…

This study compares three different programs to help pregnant women maintain a healthy weight during and after pregnancy. About 795 women who are Black, Hispanic, or on Medicaid will join from early pregnancy until one year after giving birth. The goal is to see which program wor…

This study tests whether giving three drugs (gemcitabine, docetaxel, and toripalimab) before standard radiation can safely improve outcomes for people with a specific throat cancer caused by the Epstein-Barr virus. About 24 adults with advanced but not spread cancer will receive …

This study tests a drug called efgartigimod in 5 adults with IgG4-related disease, a condition that causes swelling in glands and organs. Participants receive weekly injections for 12 weeks. The goal is to see if the drug reduces swelling in the tear glands, saliva glands, or pan…

This early-stage trial tests whether statins, a common cholesterol medicine, can prevent strictures (narrowing) in the gut for adults with Crohn's disease. About 20 participants will take either statins or a placebo daily for 6-12 months after surgery. Researchers will check for …

This study is testing a new way to deliver radiation therapy for liver cancer. Instead of multiple sessions over weeks, patients receive a single, high-dose treatment guided by real-time MRI scans. The approach aims to be more precise and convenient. The trial will enroll 62 adul…

This early-phase trial tests a personalized, accelerated radiation schedule (HART) combined with chemotherapy for people with locally advanced lung cancer. The goal is to see if this faster treatment can control the disease while reducing damage to the lungs and esophagus. About …

This study tests whether adding fermented foods to the diet can reduce inflammation and improve quality of life in people with mild-to-moderate ulcerative colitis. About 21 adults with confirmed UC and active symptoms will eat fermented foods and be monitored for changes in a sto…

This study tests whether dipyridamole, a drug used for heart conditions, can raise phosphate levels in kidney transplant patients who develop low phosphate (hypophosphatemia). About 90 adult kidney transplant recipients will receive dipyridamole or a placebo. The goal is to see i…

This early-phase study tests a new treatment called B7-H3 CAR T cells for adults with ovarian cancer that has returned and is no longer responding to standard chemotherapy. The treatment involves taking a patient's own immune cells, modifying them in a lab to better recognize and…

This study tests whether a non-invasive brain stimulation technique called deep TMS can help veterans reduce or stop methamphetamine use. Thirty participants with moderate to severe methamphetamine use disorder will receive the treatment while researchers track brain activity and…

This early-phase study is testing whether a second infusion of the CAR T-cell therapy axicabtagene ciloleucel (Axi-Cel-2) is safe for adults with high-risk large B-cell lymphoma whose cancer came back or didn't respond to the first standard CAR T treatment. About 20 participants …

This study tests whether giving a second type of CAR T-cell therapy (targeting CD22) after the standard CD19 CAR T treatment is safe and can help children and young adults whose B-cell leukemia has returned or not responded to other treatments. About 20 participants will receive …

This study tests the Cardiohelp device, a heart-lung machine for children with severe heart failure, to see if it is safe and works well for up to 30 days. It also compares two blood thinners, heparin and bivalirudin, to find which causes fewer bleeding or clotting problems. Abou…

This early-phase trial tests a new treatment for children and young adults with medulloblastoma or similar brain tumors that have come back or not responded to standard therapy. The treatment uses the patient's own immune cells, modified to recognize and attack tumor cells, deliv…

This early-phase study tests whether giving a radioactive drug (Lutathera) before and after surgery is safe and feasible for people with advanced neuroendocrine tumors that have spread to the liver or lymph nodes. About 10 participants will receive two cycles of the drug, then un…

This early-stage trial tests a new treatment for adults with a returning, aggressive brain cancer called glioblastoma. The therapy uses the patient's own immune cells, modified to recognize and attack the cancer, and delivers them directly into the brain. The main goals are to se…

This study tests whether injecting a man's own platelet-rich plasma (PRP) into his testicles can help him produce sperm. It includes 10 men who have already had a failed sperm retrieval procedure. The goal is to see if PRP can improve the chance of finding sperm for IVF.

This Stanford study is testing computer algorithms to better map the heart's electrical activity in people with atrial fibrillation (AF), a common heart rhythm disorder. Researchers will compare different methods to see which best identifies problem areas in the heart. The study …

This study tests a special dye that attaches to lung cancer cells and makes them glow under a camera during surgery. The goal is to help surgeons see and remove all cancer tissue more accurately. About 30 adults with lung cancer or lung metastases will receive the dye before thei…

This study tests a special dye that makes brain tumor cells glow under a camera during surgery. The goal is to help surgeons see and remove more of the tumor while sparing healthy brain tissue. About 46 adults with malignant glioma or vestibular schwannoma will receive the dye be…

This study is testing whether a dye called panitumumab-IRDye800 can safely help surgeons see brain tumors more clearly during surgery in children and young adults aged 6 months to 25 years. The dye is given before surgery and makes tumor tissue glow under a special camera, helpin…

This study tests a low-risk surgical procedure called LYMPHA, done at the same time as breast cancer lymph node removal, to prevent lymphedema—a chronic, painful arm swelling. About 80 women undergoing breast cancer surgery will be randomly assigned to receive LYMPHA or standard …

This study tests whether tranexamic acid (TXA), a drug that reduces bleeding, can prevent arthritis after an ACL tear. About 50 people aged 18-30 who recently tore their ACL will receive TXA or a placebo. Researchers will check joint inflammation and cartilage health using MRI an…

This study involves 600 adults having their first open-heart surgery. Doctors will use a temporary pacemaker to test if the heart is prone to atrial fibrillation (AFib) during the operation. Those who show risk will be randomly assigned to receive the drug amiodarone or standard …

This study tests a single online class called Empowered Relief, delivered in Spanish to adults with chronic pain. The class teaches pain relief skills, and participants fill out surveys right after, at 2 weeks, and at 1 month. The goal is to see if the class is helpful and satisf…

This study compares two ways of delivering Pivotal Response Treatment (PRT), a behavioral therapy for autism, to young children aged 2 to 5 with language delays. One group gets therapy at a center, another at home, and a third group continues their usual care. The goal is to see …

This Stanford study tests whether having a dream while under anesthesia can reduce PTSD symptoms. In a small Phase 2 trial, 42 adults with PTSD will receive either deep sedation to trigger dreaming or light sedation without dreaming. Researchers will compare changes in PTSD sever…

This study tests whether an online Spanish course can teach parents of young children with autism to use Pivotal Response Treatment (PRT) to boost communication and social skills. Forty Spanish-speaking families with children aged 2 to 5 will take 12 weeks of online lessons, atte…

This study tests whether a small, wearable device that sends electrical pulses to nerves can reduce chronic neuropathic pain in the lower back, pelvis, and legs. About 148 adults will either receive standard medical care alone or standard care plus the nerve stimulation device fo…

This study is testing whether using local anesthesia with sedation (called MAC) is as good as or better than general anesthesia for people having 1-3 level lumbar decompression surgery for spinal stenosis. Researchers will compare pain, disability, and recovery in 100 adults aged…

This small study from Stanford tests whether rapid, non-invasive brain stimulation can reduce the urge to hoard. Ten adults with hoarding disorder will receive the treatment and report changes in their acquiring habits. The goal is to see if this safe, outpatient procedure can ea…

This study tests whether zolpidem, a sleep medication, can improve sleep in children and teens with autism. About 26 participants aged 8-17 will receive either the drug or a placebo for 8 weeks, then switch. The goal is to see if the drug helps them fall asleep faster and sleep m…

This study tests a non-invasive device that uses pulsed radiofrequency to treat chronic nerve pain after injury. Researchers want to see if it can reduce pain without drugs or surgery. The trial is for adults aged 18 and older with nerve pain from a past injury or surgery.

This study tests whether a cardiac rehabilitation program can help adults with Fontan failure walk more each day and improve their exercise ability, frailty, and quality of life. Researchers will compare the rehab group to those receiving usual care. The trial aims to enroll 50 p…

This study is testing whether a device that sends gentle magnetic pulses (PEMF therapy) can help reduce pain after shoulder or knee surgery. About 76 adults having these surgeries will use the device or a fake one for 10 days after their operation. Researchers will measure pain l…

This pilot study tests a new 12-week group therapy program called BEAR-SI for women aged 18-75 who have experienced interpersonal trauma and currently have suicidal thoughts. The program combines psychological skills, education about trauma, and physical self-defense training. Th…

This study compares two approaches to supportive cancer care for nearly 3,000 adults with cancer. One group gets information through email or their health record, while the other works one-on-one with a lay health worker over 12 months. The goal is to see which model better impro…

This study compares two methods of delivering local anesthetic through a nerve block catheter after surgery: a continuous infusion versus scheduled bolus doses. Researchers will measure pain scores and opioid use in 240 adults. The goal is to find which approach provides better p…

This study tests whether taking melatonin, a natural sleep aid, can help teens aged 12-18 sleep better and recover after major bone or spine surgery. Researchers will give some teens a fast-dissolve melatonin pill and others a placebo to see if it improves sleep quality, pain, an…

This study tests whether virtual reality (VR) field trips can improve the emotional well-being and learning of children aged 5 to 17 who are stuck in the hospital. Participants will wear a VR headset to visit famous landmarks and then do a hands-on science experiment. Researchers…

This study tests whether a motion-capture system called OptiTrack, paired with a game called Snipperfingers, can make physical therapy more engaging for children aged 6 to 17 who are staying in the hospital. Kids who are medically cleared to stand and move their upper body will p…

This study tests whether using an aromatherapy inhaler (with lavender or peppermint) can help reduce distress and improve coping for patients recovering from a stem cell transplant. About 50 adult patients will use the inhaler during their hospital stay. The goal is to see if thi…

This study tests whether adding dextromethorphan (a cough suppressant) to fluoxetine (an antidepressant) can safely reduce symptoms of obsessive-compulsive disorder (OCD) and related conditions like body dysmorphic disorder. About 60 adults in California will take the combination…

This study compares two LASIK techniques to see which one corrects nearsightedness and astigmatism better. 70 adults aged 22 and older with healthy eyes will have one eye treated with each method. The goal is to find out if one approach leads to sharper vision without glasses.

This study tests whether virtual reality (VR) can help children and young adults with cancer be more physically active while in the hospital. 40 participants aged 10-25 will try both VR-assisted physical therapy and traditional physical therapy to see which one gets them moving m…

This study tests whether people with knee osteoarthritis can learn to change how they walk using a device that vibrates to give feedback on muscle use. The goal is to reduce the force on the knee joint, which may ease symptoms. About 31 participants will try this training on a tr…

This study tests whether adding insomnia treatment to standard suicide-focused therapy helps teens at high risk for suicide. About 44 teens aged 12-18 with sleep problems and a history of self-harm will receive either therapy alone or therapy plus a digital sleep program. Researc…

This pilot study tests a non-invasive 3D-printed external device to help men with erectile dysfunction achieve satisfactory sexual intercourse. Nine men with moderate to severe ED from any cause, along with their female partners, will try the device. The goal is to see if it is s…

This study tests a new extended-release version of sodium oxybate taken as a single dose at bedtime for children with narcolepsy type 1. Researchers want to see if kids prefer it over current twice-nightly options and if it is safe and convenient. About 36 children from Stanford …

This study tests whether a proven sleep therapy (CBT-I) can improve how the brain regulates emotions, helping treat depression and anxiety. Researchers will use brain scans to see changes in emotion networks. 120 adults with insomnia and depression will participate. The goal is t…

This study tests whether guanfacine, a medication typically used for blood pressure, can improve brain network function and reduce cognitive problems in people with depression. Researchers will enroll 162 adults aged 18-60 who are currently experiencing a major depressive episode…

This study looks at the best way to clean wounds during surgery for advanced pilonidal disease. It compares standard saline to a special solution called hypochlorous acid to see which helps wounds close faster. About 72 people having surgery for stage 3 pilonidal disease will tak…

This study looks at whether a treatment called DTPA chelation can help people with Gadolinium Deposition Disease (GDD), a condition caused by gadolinium from MRI contrast dyes staying in the body. Researchers will give 50 adults at least five two-day treatment sessions and track …

This study tests whether injecting a long-lasting numbing medication (Exparel) into the side of the nose can reduce severe face and headache pain. About 15 adults with conditions like migraine or cluster headache will receive either the drug or a placebo, then switch groups. The …

This study tests two simple early treatments—writing about the experience (Written Exposure Therapy) and guided breathing exercises (Capnometry Guided Breathing)—to see if they can reduce PTSD symptoms in new mothers after a traumatic childbirth. About 70 women who recently gave …

This study tests a virtual program where parents learn to help their autistic child cope with insistence on sameness behaviors, like needing routines or getting upset over changes. About 30 children aged 6 to 10 with autism and average intelligence will take part. The goal is to …

This pilot study at Stanford University is testing whether giving rTMS (a non-invasive brain stimulation) in the morning or evening works better for treating insomnia. Ten adults with insomnia will receive ten sessions over two weeks. Researchers will track sleep quality and brai…

This pilot study looks at whether a new wheeled mobility tool helps people move around more easily after total knee replacement. About 19 adults aged 18-99 who can walk with at most a cane or crutch before surgery will use the device. Researchers will track how much they use it a…

This study tests a new drain system (Interi) against standard drains in 20 women having implant-based breast reconstruction after mastectomy. The goal is to see if the new drain reduces complications, shortens drain time, and improves patient comfort. Participants must be 18-65, …

This study tests a new type of spinal cord stimulation for people with long-lasting pelvic pain that hasn't improved with other treatments. The device automatically adjusts its energy based on real-time feedback to better target pain. Ten adults will be enrolled to see if it safe…

This study tests whether esomeprazole, a drug usually used for heartburn, can help improve social communication in young children with autism. Researchers will give the drug to 25 children aged 2 to 6 for 12 weeks and measure changes in social behavior. The goal is to see if this…

This study compares a combination of ibuprofen and acetaminophen to the opioid oxycodone for managing pain after thumb surgery (trapeziectomy) for osteoarthritis. About 121 adults will be randomly assigned to one of the two pain regimens and tracked for 30 days. The goal is to se…

This study tests whether a smartphone app that uses neurofeedback can help people with mild to moderate depression. Participants will use the app to learn about positive emotions and brain chemicals. The goal is to see if the app is safe and effective, and to prepare for a larger…

This study at Stanford University is testing whether simple stress reduction practices like breathing exercises (cyclic sighing, box breathing) and hypnosis can lower anxiety. Eighty adults will practice daily for four weeks. Researchers will measure changes in brain activity, he…

This study tests a smart system that reads facial expressions during computer-based brain training to keep older adults engaged and motivated. The goal is to help people aged 60-89 who are at risk for Alzheimer's stick with at-home cognitive exercises. Researchers will compare tr…

This study tests whether N-acetylcysteine (NAC), a well-tolerated nutritional supplement, can reduce restricted and repetitive behaviors in children with autism. About 144 children aged 3 to 12 will receive either NAC or a placebo for 12 weeks. Researchers will measure changes in…

This study tests a new device called the Blossom Smart Expander for women having breast reconstruction or augmentation. Instead of weekly needle injections to slowly stretch the skin, this device automatically fills with a tiny amount of saline over time. The goal is to see if it…

This early-stage study tests whether insulin eye drops are safe for people with glaucoma and other optic nerve conditions. Researchers will monitor 52 participants for side effects over 1-2 months. The goal is to see if this approach can be developed further to protect vision.

This study looks at whether a 12-week early intervention program helps improve social communication in preschoolers (ages 2-5) with developmental disorders like autism or intellectual disability. Children attend either a center-based preschool or home sessions for 12 hours each w…

This study tests whether using a virtual reality (VR) headset can make behavioral activation therapy more effective for older adults (65+) with major depression. Thirty participants will use VR to engage in activities that boost mood, and researchers will measure changes in depre…

This study tests whether Botox injections into the skin can reduce the number of painful attacks in people with trigeminal neuralgia, a severe facial pain condition. It includes 20 adults who have not gotten enough relief from medications or are not candidates for surgery. Partic…

This study tests whether diphenhydramine, a common allergy medicine that makes people sleepy, can improve sleep in children and teens with autism. About 26 participants aged 8 to 17 will receive either the drug or a placebo for several weeks, then switch. The goal is to see if it…

This study compares two online treatments for chronic pain: an 8-week cognitive behavioral therapy program (16 hours total) and a single 2-hour pain relief skills class. Researchers want to see which works better for reducing pain intensity and interference. The study will enroll…

This study tests whether a special 5-day diet that mimics fasting can lower inflammation and improve quality of life in people with mild to moderate ulcerative colitis. Participants will follow the diet for three cycles while researchers track symptom changes. The goal is to see …

This study tests whether suvorexant, a sleep medication, helps teenagers (13-17 years) with autism fall asleep faster and stay asleep longer. About 26 participants will receive either the drug or a placebo, then switch after a period. The goal is to see if it improves sleep quali…

This study compares the Gokhale Method posture therapy to standard physical therapy for people with chronic lower back pain. Researchers want to see which approach works better for reducing pain and improving daily function. The study involves 100 adults aged 18-65 with moderate …

This study tests a simpler way for paramedics to treat seizures in children. Instead of calculating doses, paramedics will use age-based, pre-set doses of a seizure-stopping medicine given as a shot or nasal spray. The goal is to see if this approach stops seizures before the chi…

This Stanford study looks at 200 people with persistent atrial fibrillation (AF) who are scheduled for ablation or Maze surgery. Researchers will map the heart's electrical activity to see if the size of organized areas predicts whether the procedure works. The goal is to better …

This early-phase study at Stanford University is testing the statin drug rosuvastatin in 15 people with primary sclerosing cholangitis (PSC), a liver disease with no cure. Researchers want to see how the drug changes bile acids and gut bacteria, hoping to better understand why PS…

This pilot study tests whether wearable devices and smartphone surveys can help spot emotional struggles in adolescents and young adults recently diagnosed with cancer. Twenty-five participants will wear a smartwatch and answer quick questions about mood, sleep, and stress for 10…

This study follows 800 children who have received a stem cell transplant to track their long-term health. Researchers will collect medical data and tissue samples over time to understand common problems survivors face. The goal is to create a database that helps doctors improve f…

This study is testing whether giving low-income families a monthly cash gift plus support from a community health worker can improve child health, reduce poverty, and help families use services like doctor visits and food assistance. Researchers will follow 2,400 families in San …

This pilot study looks at whether giving dialysis on the same day as surgery is better than not giving it for people with end-stage kidney disease. About 30 participants will be randomly assigned to one of two schedules. Researchers will track safety issues like electrolyte probl…

This study uses a non-invasive brain stimulation technique called TMS to see if it can change brain activity in people with schizophrenia. Researchers will measure brain waves before and after stimulation to understand how the hippocampus works in this condition. The goal is not …

This study is a registry that follows up to 5,000 adults who have an IVC filter placed or removed. An IVC filter is a small device placed in a large vein to prevent blood clots from traveling to the lungs. The goal is to collect data on how well the filter works and any complicat…

This study follows up to 500 children and young adults (up to age 26) with B-cell leukemia or lymphoma who have received immunotherapy like Kymriah or blinatumomab. Researchers will use surveys and medical records to track survival, remission, and unmet needs. No new treatment is…

This study is building a registry of people with gastric cancer, a family history of it, or a specific gene mutation (CDH1). Participants fill out online questionnaires and provide saliva, blood, or tissue samples. The goal is to learn more about what causes stomach cancer and ho…

This study is collecting medical information from 2000 people with advanced mycosis fungoides or Sézary syndrome, two rare types of skin lymphoma. The goal is to create a tool that helps doctors predict which patients are at higher or lower risk, so they can tailor treatments mor…

This study at Stanford University collects tissue and blood samples from 100 adults with or at high inherited risk for stomach, esophageal, or related cancers. Researchers aim to understand how genes and proteins contribute to cancer development. The study does not test any treat…

Stanford University is recruiting 2,500 people with possible allergies to study how the body reacts. Researchers will use skin tests and blood samples to learn about the genetic and cellular causes of allergies. The goal is to improve diagnosis and understanding, not to test a ne…

This study is screening people with recessive dystrophic epidermolysis bullosa (RDEB), a rare genetic disease that causes painful blisters and open wounds from minor skin contact. Researchers at Stanford want to learn more about the disease and the patients' cells to develop new …

This study compares two widely used drug classes—anti-convulsants and anti-depressants—for treating chronic pain in 450 real-world patients. Unlike typical trials that exclude many patients, this one includes people with other health issues to get results that apply to more peopl…

This study at Stanford University tests whether augmented reality (AR) or virtual reality (VR) goggles can help doctors perform ultrasound-guided procedures, such as nerve blocks or placing IV lines, more precisely. About 100 adults having these procedures will use the AR/VR devi…

This study looks at embryos that were found to have extra or missing chromosomes (aneuploidy) or a mix of normal and abnormal cells (mosaicism) during genetic testing. Researchers want to see how often these embryos lead to a healthy baby and whether the pregnancy or child has an…

This study collects tumor and blood samples from 3,300 people at high genetic risk for breast, ovarian, and related cancers. Researchers want to learn how these cancers develop and how well treatments work. Participants include those with BRCA1/2 or other gene mutations, or a str…

This Stanford study looks at how ultra-processed foods (like sugary drinks and snacks) affect brain areas involved in reward, attention, and memory in 162 teenagers aged 13-15. Participants will have brain scans while tasting and viewing different foods, and will also eat from a …

This study tests a web-based program for romantic partners who are worried about their loved one's drinking. Researchers will use daily surveys from both partners to build personalized feedback that helps the concerned partner communicate better and motivate change. The goal is t…

This study from Stanford University is looking at what happens inside the body when people with heart failure exercise. Researchers will measure thousands of proteins in the blood before and after a single workout, and again after a 12-week cardiac rehab program. By comparing the…

This study looks at how well the flu vaccine works in people who have had COVID-19, including those with long-term symptoms like fatigue or diabetes. Researchers will compare immune responses between 230 adults and children (ages 9-64) who had COVID-19 and those who did not. The …

This study looks at whether a daily ergothioneine supplement can raise the levels of this nutrient in the blood of people with kidney failure who are on dialysis. Dialysis removes waste but also lowers ergothioneine, a natural dietary compound. The study will enroll 28 participan…

This study uses EEG (a non-invasive brain wave test) to find patterns in the brain that might predict how chronic low back pain changes over time. Researchers will track 130 adults with chronic low back pain and healthy volunteers for up to 5 months. The goal is to develop better…

This study aims to understand how repetitive brain stimulation (TMS) changes brain activity in people with depression and epilepsy. Researchers will use special brain recordings to see exactly what happens during TMS. The goal is to find better ways to use TMS to treat depression…

This study compares whole-body MRI, PET/MR, and PET/CT scans to see which is best at finding tumors in children and young adults with solid cancers like lymphoma or osteosarcoma. Researchers will measure how many tumors each method detects and how active the tumors are. The goal …

This study aims to learn more about oropharyngeal carcinoma, a type of throat cancer that can be linked to HPV. Researchers will collect blood samples from 1,000 patients before treatment and at six follow-up visits, and also gather tumor tissue when available. The goal is to bet…

This Stanford study watches 20 young women for 28 days to see how sleep, body rhythms, and the menstrual cycle work together. Researchers track movement, heart rate, and other body signals. The goal is to learn how these cycles might affect injury risk, not to test a treatment.

This study looks for proteins and other markers in the blood of 2000 adults with or suspected of having cancer. The goal is to find markers that may help doctors confirm a cancer diagnosis, choose the right treatment, and predict how well a patient will respond or if the cancer w…

This study looks at how adolescents and young adults (ages 15-29) with cancer prefer to be involved in decisions about their treatment. Researchers will use made-up scenarios to see if participants want an active, collaborative, or passive role. The goal is to better understand w…

This study tests whether an online training course can teach parents of children with autism (ages 2-5) a therapy technique called Pivotal Response Treatment. Researchers will check if parents learn the technique and if children's communication improves. 44 families will particip…

This study tests a parent coaching program for parents of teens (ages 12-18) hospitalized for suicidal thoughts, suicide attempts, or self-harm. Parents receive coaching on safety planning and parenting skills, plus help connecting to follow-up care. The goal is to see if this ex…

This study tests a simple blood test (liquid biopsy) to see if it can tell which triple-negative breast cancer patients will benefit from the drug capecitabine after standard chemotherapy. About 40 adults with leftover cancer after chemo will give blood samples before and during …

This study is creating a simple tool to measure how well the body uses insulin and overall heart health in children and teens with severe obesity. Researchers will use data from fitness trackers and glucose monitors, along with blood tests, to understand how activity and blood su…

This study looks at whether a program called Food FARMacia is practical and well-liked by families who struggle to afford enough food. About 80 families with babies aged 6 to 18 months will get nutrition advice and regular food distributions. The goal is to see if this approach c…

This study is testing a new method to collect and analyze cells and molecules from the uterus using a gentle wash during gynecologic surgery. Researchers will enroll 50 women to see what types of cells and genetic material can be found in the fluid. The goal is to learn more abou…

This study aims to understand how ketamine causes dissociative symptoms—feelings of detachment from oneself or reality—in people with epilepsy. Researchers will give ketamine to 20 adults staying in Stanford's epilepsy monitoring unit and measure their dissociative experiences us…

This early-stage study at Stanford tests whether giving magnetic brain stimulation during sleep is safe and practical for people with major depression. Fifteen adults who have not gotten better with at least one antidepressant will receive both real and fake stimulation in separa…

This study aims to uncover the genes and proteins that drive head and neck cancer. Researchers at Stanford will analyze tissue from 500 patients undergoing surgery to better understand how the disease develops and progresses. The goal is to lay the groundwork for future diagnosti…

This study tests whether hearing aids with built-in sensors and artificial intelligence can assess a person's risk of falling and help them hear better in noisy environments. Researchers at Stanford University will enroll 350 adults aged 55 and older who already wear hearing aids…

This study follows 600 adults aged 35–84 who are at higher risk for stomach cancer, including those with precancerous changes like intestinal metaplasia. Researchers collect tissue and blood samples during routine endoscopies to track how these changes progress or reverse over ti…

This study uses surveys and phone interviews to learn how COVID-19 impacts people with cancer. Researchers want to understand the challenges these patients face during the pandemic. About 50 adults with cancer will take part. No treatments or medications are involved.

This study aims to improve depression treatment by finding better ways to measure brain excitability. Researchers at Stanford will use a technique called TMS (transcranial magnetic stimulation) to stimulate the brain and record the brain's electrical responses. 145 adults with mo…

This study is testing two experimental insulin formulas to see if they work faster than a current insulin (Lyumjev) in adults with type 1 diabetes. Twenty participants will receive each insulin after a meal, and blood samples will be taken to measure how quickly the insulin peaks…

This study collects tumor tissue from people with Hodgkin's or non-Hodgkin's lymphoma to learn more about the cancer cells. It does not test any new treatment. Participants must already be scheduled for a routine procedure to remove lymph nodes. The goal is to better understand t…

This study from Stanford University aims to understand why people's blood sugar levels respond differently to the same foods. Researchers will use continuous glucose monitors (CGMs) in 100 healthy adults, people with prediabetes, and those with type 2 diabetes to track blood suga…

This study tests a personalized mobile tool to help women with overactive bladder (OAB) start and stick with treatment. About 30 women will use the app to learn about their condition, track symptoms, and get support. The goal is to see if the tool improves bladder health knowledg…

This study tests whether a safe, non-invasive technique called caloric vestibular stimulation (using warm or cool water in the ear) can temporarily improve insight in people with obsessive-compulsive disorder, body dysmorphic disorder, or illness anxiety disorder. Researchers wil…

This study looks at whether brain scans can help predict which young children with autism will improve the most with a behavioral therapy called Pivotal Response Treatment (PRT). The study involves 36 children aged 2 to 4 years old. Some children receive PRT right away, while oth…

This study looks at whether analyzing the DNA of a patient's tumor can help doctors recommend more effective treatments for metastatic cancer. Researchers will test tumor samples from 100 adults with advanced, incurable cancer to find genetic changes that match existing drugs or …

This study looks at how ketamine causes feelings of dissociation (feeling detached from yourself or reality). Researchers will give ketamine to 120 psychiatric inpatients and measure their dissociative symptoms using a standard scale. The goal is to understand the brain circuits …

This observational study at Stanford University looks at how levels of carotenoids (natural pigments from fruits and vegetables) in the skin relate to immune aging and skin health. Researchers will measure skin carotenoids and compare them with aging markers like wrinkles, inflam…

This study looks at how a single dose of N-acetylcysteine (NAC), a common supplement, changes brain chemistry in children with autism who have repetitive behaviors. Researchers will use brain scans and EEG to measure these changes. The goal is to understand why NAC might help red…

This study tests whether trained community health workers (called Promotores) can help Latino/a adults learn about mental health services and feel more comfortable seeking help. About 192 participants from specific San Jose zip codes will attend six educational sessions. The goal…

This study is a registry that collects contact information from people of all ages who are interested in joining future clinical trials for allergies or asthma. No treatments or tests are given—it simply helps researchers find volunteers for upcoming studies. Anyone from 0 to 100…

This study screens up to 1,000 people with possible food allergies to see if they qualify for future clinical trials at Stanford. Participants undergo food challenges and skin tests to confirm their allergies. The goal is to build a pool of diagnosed individuals ready for upcomin…

This study at Stanford University is testing whether a computer program can help doctors predict which patients with atrial fibrillation (an irregular heartbeat) will benefit from a procedure called ablation. About 120 adults who are already scheduled for ablation will have their…

This study looks at how ketamine affects the brain to reduce symptoms of obsessive-compulsive disorder (OCD). Researchers will measure changes in OCD severity using a standard scale. The study involves 150 adults aged 18-65 with OCD who have not responded to at least one standard…

This study aims to create a digital decision-making aid for older adults with heart failure who are considering getting an implantable cardioverter-defibrillator (ICD). The tool will help patients weigh the benefits of preventing sudden cardiac death against the downsides of the …

This study compares an AI platform to human experts in evaluating how well anesthesiology trainees communicate when disclosing a medical error. About 45 residents and fellows will participate in a simulated conversation, and their communication skills will be scored by both the A…