Stanford University

This early-phase trial tests whether baricitinib, taken with a steroid-sparing medication, can reduce inflammation in the hearts of adults with active cardiac sarcoidosis. Ten participants will take the drug for up to 16 weeks and undergo PET scans to measure changes in heart inf…

This study tests whether it is safe to stop the anti-rejection drug tacrolimus early after a stem cell transplant. About 50 people with blood cancers or bone marrow disorders will receive a modern GVHD prevention method and then stop tacrolimus by day 88. The goal is to see if th…

This early-stage study tests whether a mixture of 157 live bacteria from healthy stool, called MITI 001, is safe for people with diarrhea-predominant irritable bowel syndrome (IBS-D). The trial will enroll 13 adults whose IBS is linked to gut microbiome problems. Researchers hope…

This study compares two wound-cleaning solutions used during surgery for advanced pilonidal disease. About 72 people will be randomly assigned to receive either standard saline or hypochlorous acid (Vashe) to see which leads to faster wound healing. The goal is to find the best w…

This study will see if using artificial intelligence to find calcium buildup in heart arteries on chest CT scans that people already had can help doctors start or adjust cholesterol-lowering medications. About 120,000 adults with known heart disease or significant calcium buildup…

This study will see if starting an automated insulin delivery (AID) system within 2 weeks of a type 1 diabetes diagnosis helps young people manage their blood sugar better and stick with the system long-term. About 16 participants will be followed for a year to see how many conti…

This study tests a new way to study psilocybin (the active ingredient in magic mushrooms) for depression. To make the research more reliable, participants will be given psilocybin or a placebo while under general anesthesia, so they won't know which they received. The goal is to …

This study compares two ways of giving acetaminophen (Tylenol) after lumbar spine fusion surgery: by mouth or through an IV. 180 adults will be randomly assigned to one of the two groups. The goal is to see which method provides better pain relief and helps patients recover faste…

This study tests whether a 2-week liquid diet is practical and tolerable for adults with chronic pancreatitis who have bothersome stomach symptoms. Researchers will see if participants can stick with the diet and drink enough of the formula. The goal is to find a new way to manag…

This study tests a new device called the Origin Intubation System, designed to help doctors place a breathing tube more easily and safely on the first try. About 15 adults having planned surgery with general anesthesia will take part. The goal is to see if this tool reduces faile…

This study tests whether giving a medicine called dexmedetomidine during a second-trimester dilation and evacuation (D&E) can lower feelings of grief and stress after the procedure. About 100 people having a D&E in the operating room will be randomly assigned to receive the drug …

This study tests whether automated text message reminders can encourage people with hearing loss to get hearing aids. Only about 30% of those who need hearing aids actually get them. Researchers will enroll 190 adults who have been recommended for hearing aids and send them text …

This study tests whether listening to spatial audio (a 3D sound experience) can help people tolerate heat pain better. One hundred healthy adults will have heat applied to their skin, once with the audio device and once without, to see if the sound changes their pain threshold. T…

This study tests if Acoustic Resonance Therapy (ART) — a non-invasive treatment that uses sound vibrations to clear nasal passages — can ease symptoms of Empty Nose Syndrome (ENS). About 40 adults who have had past turbinate surgery will receive ART. The goal is to see if it redu…

This study tests whether a short virtual reality (VR) mindfulness experience can improve well-being and reduce anxiety in hospitalized adults. About 42 patients will try VR and then compare their feelings to standard hospital care. The goal is to see if this simple, drug-free too…

This study tests whether a device that plays sounds based on your body signals (audio biofeedback) can help people handle cold pain better. One hundred healthy adults will try the device and also a session with nothing, to compare. The goal is to see if this simple, non-drug appr…

This study will test if a special audio game called Mystic Pets can help distract children (ages 4-17) from emotional distress while they are in the hospital. About 20 kids will try the game and give feedback on whether they liked it and if it was easy to use. The goal is to see …

This study looks at whether using virtual reality (VR) or augmented reality (AR) headsets can help children aged 4-17 feel less anxious and experience less pain during minor procedures like lumbar punctures or heart catheterizations. About 200 kids will be randomly assigned to us…

This study looks at whether waking up more slowly from anesthesia can help people think clearer, have less pain, and leave the recovery room sooner after lower-leg or foot surgery. About 300 adults having planned surgery with nerve blocks will be randomly assigned to either a lon…

This study tests whether augmented reality (AR) and virtual reality (VR) can help teens aged 11-17 who are extremely afraid of needles. About 20 participants will use a special headset to practice facing their fear in a safe, virtual environment. The goal is to reduce their anxie…

This study tests whether a stellate ganglion block (an injection near nerves in the neck) can reduce symptoms of Postural Tachycardia Syndrome (POTS), a condition that causes a rapid heart rate upon standing. Twenty adults with POTS will receive either the real injection or a sha…

This study tests whether community health workers (called promotoras) can help Latinx patients recently diagnosed with colorectal cancer. Sixty participants will either get a health worker to guide them or just a list of resources. The goal is to see if this support improves qual…

This study looks at whether a lower dose of the drug cabergoline can safely prevent breast pain, swelling, and leaking after a second-trimester abortion or pregnancy loss. The standard dose can be expensive and cause side effects. Researchers will compare the lower dose to the us…

This study aims to find the best combination of dietary strategies for weight loss using a fully digital program. Researchers will test four approaches: limiting high-calorie foods, eating within set time windows, and increasing protein or fiber intake. 208 adults with overweight…

This study will test whether a health tracking platform can improve the health of 1,000 older adults (65+) who are at risk for frailty. Over one year, participants will use the platform to monitor their health, and researchers will see if it helps them stay stronger and more inde…

This study tests whether a new educational program helps high school students in construction career classes understand how building design impacts community health and environmental fairness. About 40 students aged 14-18 will be randomly assigned to either the new curriculum or …

This study looks at how an implanted vagus nerve stimulator (VNS) changes brain and heart signals in people with treatment-resistant depression. Researchers will use EEG and ECG to measure brainwave patterns and heart activity. The goal is to understand how VNS helps improve mood…

This pilot study tests a new PET camera designed specifically for breast imaging, with very high resolution. The main goal is to see if the camera works well in a clinic setting and produces clear images. About 20 people with biopsy-confirmed breast cancer will take part. The stu…

This study collects basic health information like blood pressure, heart rate, and weight from 50 adults aged 18 to 64. Researchers will use this data to develop a device that can monitor blood pressure continuously without needles or cuffs. The study does not test any treatment o…

This study explores whether a non-invasive technique called vagus nerve stimulation can help improve memory in healthy older adults (ages 65-80) compared to younger adults (ages 18-30). Researchers will also look at how gut health and early signs of Alzheimer's disease affect the…

This study looks at whether medications given before surgery make people feel good or like them. Researchers will ask 100 adults to rate their drug liking and measure brain activity. The goal is to understand how these drugs affect feelings, not to treat any disease.

This study will compare two different ways of giving epidural pain relief during labor to see which one makes mothers more satisfied. About 150 people planning a vaginal delivery who request an epidural will take part. They will receive standard care and fill out short surveys ab…

This study looks at how the brain responds when visual information is turned into patterns of sound or touch. Researchers will use brain scans and simple tasks to see if blind and sighted people can learn to use these signals. The goal is to understand brain adaptation, not to tr…

This observational study tests whether a noninvasive finger monitor can predict how pregnant women, including those with severe preeclampsia, respond to fluids. Researchers will compare the finger device's accuracy to standard ultrasound methods. The goal is to find a simpler way…

This study explores how new mothers use a digital app designed to support recovery after childbirth. The app collects wellbeing data and offers tailored guidance. Researchers will ask 60 participants about the app's ease of use and helpfulness during the first 12 weeks after deli…

This study looks at whether the kind of education patients receive about a one-time propofol sedation treatment can change how well it works for depression. Twenty adults with moderate to severe major depressive disorder will get a single propofol infusion and be randomly assigne…

This study uses smartphone sensors to track physical activity and heart health in 15,000 US adults. Participants answer health questions and may receive personalized activity prompts. The goal is to learn how daily movement relates to cardiovascular risk, not to test a treatment.

This study tests whether personalized text messages written by an AI can encourage people to be more active. Fifty adults with an iPhone and Apple Watch will receive daily texts for two weeks—some tailored to them, some generic. Researchers will track activity via HealthKit to se…