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Researchers to measure drug liking during procedures

NCT ID NCT07348172

Knowledge-focused Sponsor: Stanford University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to understand how medications used during medical procedures affect patients' feelings of liking or disliking the drug. About 100 adults scheduled for surgery will rate their drug liking and have their brain activity measured. The results will help doctors better understand the effects of these medications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Early phase 1

The earliest testing in people: a first look at safety, in a very small group.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

Mar 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * American Society of Anesthesiologists (ASA) physical status classification of I, II or III * Candidates who are expected to receive fentanyl up to 3 mcg/kg IBW for their scheduled for surgery or procedure Exclusion Criteria: * Craniofacial abnormalities * Known or suspected difficult intubation or mask ventilation * Known or suspected need for rapid sequence induction and intubation * Allergies or hypersensitivities to amisulpride or fentanyl * Clinically significant pulmonary disease, such as chronic obstructive lung disease requiring long-term oxygen therapy, or other conditions that, in the study team's judgment, may increase the risk of severe respiratory depression with opioid administration * History of long QT syndrome * Any heart rhythm other than normal sinus rhythm (including but not limited to atrial fibrillation, atrial flutter, paced rhythms, ventricular tachycardia, or any supraventricular tachycardia) * History of Torsades de Pointes * History of psychosis * History of movement disorders e.g. Parkinson's Disease * Past chronic use of anti-psychotics * Current use of amisulpride, droperidol, levodopa, lithium, clozapine, metoclopramide, benzodiazepines * Current use of opioids * History of opiate abuse within the last 3 years * Known or suspected severe chronic pain condition that require use of opiates or limit daily activities * History of pheochromocytoma * History of concomitant prolactin-dependent tumors e.g. prolactinoma, breast cancer * Pregnancy or nursing * Failure to satisfy the investigator of fitness to participate for any other reason

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Drug liking

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Stanford Hospital

    Palo Alto, California, 94304, United States

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