Stanford University

This study tests whether giving three drugs (gemcitabine, docetaxel, and toripalimab) before standard radiation can safely improve outcomes for people with a specific throat cancer caused by the Epstein-Barr virus. About 24 adults with advanced but not spread cancer will receive …

This study tests whether a daily ergothioneine supplement can restore low levels of this nutrient in the blood of people with kidney failure who are on dialysis. Dialysis removes waste but also removes helpful substances like ergothioneine. The study will enroll 28 adults on hemo…

This study looks at how fat cells work in normal-weight people with type 2 diabetes compared to those who are overweight or don't have diabetes. Researchers will test two drugs, pioglitazone and tirzepatide, to see if they improve insulin resistance and fat storage. About 104 adu…

This study is for people with cervical cancer who need brachytherapy (internal radiation). It compares a standard 4-session plan with a shorter 3-session plan to see if the shorter option is just as effective and easier to complete. About 41 participants will be enrolled, and the…

This study tests a drug called efgartigimod in 5 adults with IgG4-related disease, a condition that causes swelling in glands and organs. Participants receive weekly injections for 12 weeks. The goal is to see if the drug reduces swelling in the tear glands, saliva glands, or pan…

This study tests whether combining counseling with a muscle relaxant (tizanidine) can help adults who have used opioids for a long time reduce their pain medication after elective surgery. About 375 participants will be randomly assigned to receive the counseling plus tizanidine,…

This early-phase study tests a new treatment called KYV-101 for people with progressive forms of multiple sclerosis (MS) that are not getting better with standard care. The treatment uses a patient's own immune cells, modified to target and destroy certain immune cells that may d…

This early-phase study tests whether specially engineered immune cells (GD2CART) can be safely made and given to children and adults with a rare, aggressive brain or spinal cord tumor called H3K27M-mutant diffuse midline glioma. The treatment involves collecting a patient's own i…

This early-phase study tests niclosamide (a drug already used for tapeworm infections) combined with standard chemotherapy in children whose acute myeloid leukemia has returned or not responded to treatment. The main goal is to find a safe dose and watch for side effects. Up to 1…

This early-stage trial tests whether statins, a common cholesterol medicine, can prevent strictures (narrowing) in the gut for adults with Crohn's disease. About 20 participants will take either statins or a placebo daily for 6-12 months after surgery. Researchers will check for …

This study compares two approaches for ductal carcinoma in situ (DCIS), a very early form of breast cancer. One group gets standard surgery to remove the cancer, while the other gets radiation therapy first, followed by surgery. The goal is to see if pre-surgery radiation can com…

This study tests a device that sends mild electrical currents through the eyes to see if it can improve vision in people with glaucoma. About 30 adults with open-angle glaucoma will receive either the real treatment or a sham (fake) version. Researchers will measure changes in vi…

This study is testing a new way to deliver radiation therapy for liver cancer. Instead of multiple sessions over weeks, patients receive a single, high-dose treatment guided by real-time MRI scans. The approach aims to be more precise and convenient. The trial will enroll 62 adul…

This early-phase trial tests a personalized, accelerated radiation schedule (HART) combined with chemotherapy for people with locally advanced lung cancer. The goal is to see if this faster treatment can control the disease while reducing damage to the lungs and esophagus. About …

This study tests whether adding fermented foods to the diet can reduce inflammation and improve quality of life in people with mild-to-moderate ulcerative colitis. About 21 adults with confirmed UC and active symptoms will eat fermented foods and be monitored for changes in a sto…

This study tests whether dipyridamole, a drug used for heart conditions, can raise phosphate levels in kidney transplant patients who develop low phosphate (hypophosphatemia). About 90 adult kidney transplant recipients will receive dipyridamole or a placebo. The goal is to see i…

This study looks at people with early-stage non-small cell lung cancer who have finished standard treatment. A blood test checks for tiny bits of cancer DNA (ctDNA) that might mean the cancer could come back. If the test is positive, participants get a drug called durvalumab to t…

This early-phase study tests a new treatment called B7-H3 CAR T cells for adults with ovarian cancer that has returned and is no longer responding to standard chemotherapy. The treatment involves taking a patient's own immune cells, modifying them in a lab to better recognize and…

This study tests whether a combination of three immunotherapy drugs (relatlimab, nivolumab, and ipilimumab) can shrink or control melanoma that has spread to the brain. About 60 adults with asymptomatic or symptomatic brain metastases will receive the drugs intravenously. The mai…

This study tests whether a non-invasive brain stimulation technique called deep TMS can help veterans reduce or stop methamphetamine use. Thirty participants with moderate to severe methamphetamine use disorder will receive the treatment while researchers track brain activity and…

This early-phase study is testing whether a second infusion of the CAR T-cell therapy axicabtagene ciloleucel (Axi-Cel-2) is safe for adults with high-risk large B-cell lymphoma whose cancer came back or didn't respond to the first standard CAR T treatment. About 20 participants …

This study tests a combination of three drugs (tagraxofusp, cladribine, and cytarabine) in 20 adults with CD123-positive acute myeloid leukemia (AML) that has come back or not responded to prior treatment. The goal is to find the best dose and see if the combo can help achieve re…

This study tests whether a non-invasive brain stimulation technique called deep TMS can help veterans with alcohol use disorder reduce relapse. One hundred participants will receive the treatment and be followed for three months to track drinking days and brain activity changes. …

This study tests an online program called Partners Connect for military couples where one partner drinks heavily. The goal is to see if the program helps the drinking partner cut back and encourages the service member to seek help. About 744 couples will participate, comparing th…

This study tests whether the da Vinci Xi robot can safely perform various surgeries in children aged 6 to 21. The goal is to see if robotic surgery works as well as traditional methods for conditions like gallbladder removal or endometriosis. Researchers will track how often the …

This study tests a much shorter course of radiation (5 days instead of the usual 25) given before surgery for soft tissue sarcoma. The goal is to see if the shorter treatment is safe and still controls the cancer. About 75 adults with sarcoma in an arm, leg, trunk, or abdomen wil…

This study aims to help people with diabetes who struggle to get enough healthy food. Participants will receive meal deliveries and nutrition education after leaving the hospital. The goal is to reduce food insecurity and improve diabetes management. About 160 adults with type 1 …

This study tests whether giving a second type of CAR T-cell therapy (targeting CD22) after the standard CD19 CAR T treatment is safe and can help children and young adults whose B-cell leukemia has returned or not responded to other treatments. About 20 participants will receive …

This study tests the Cardiohelp device, a heart-lung machine for children with severe heart failure, to see if it is safe and works well for up to 30 days. It also compares two blood thinners, heparin and bivalirudin, to find which causes fewer bleeding or clotting problems. Abou…

This early-phase trial tests a new treatment called Orca-T for people with advanced blood cancers (like leukemia) who need a stem cell transplant from a partially matched donor. The goal is to see if Orca-T can prevent serious complications such as graft failure, severe graft-ver…

This early-phase trial tests a new treatment for children and young adults with medulloblastoma or similar brain tumors that have come back or not responded to standard therapy. The treatment uses the patient's own immune cells, modified to recognize and attack tumor cells, deliv…

This early-phase study tests whether giving a radioactive drug (Lutathera) before and after surgery is safe and feasible for people with advanced neuroendocrine tumors that have spread to the liver or lymph nodes. About 10 participants will receive two cycles of the drug, then un…

This study looks at two methods of repairing a key shoulder muscle during total shoulder replacement surgery. About 100 adults getting a total shoulder replacement will be randomly assigned to standard repair or repair with a special material called Biobrace. The researchers will…

This study tests bumetanide, a drug used for high blood pressure and swelling, in 40 people with mild Alzheimer's. Researchers want to see if it is safe and tolerable. The goal is to see if this common pill can help control the disease.

This study tests a new way to care for adults with type 2 diabetes at community health centers. It uses a team of providers and technology to help patients control their blood sugar. About 120,000 patients will take part over three years. The goal is to see if this approach lower…

This study tests whether adding a special scaffold (Biobridge) to standard lymph node transfer surgery can better treat arm lymphedema, a chronic swelling condition often caused by cancer treatment. Researchers will compare the combination therapy to surgery alone in 60 adults ag…

This study tests a gene therapy called BVEC in 16 adults with a severe blistering skin condition (RDEB) who have had a type of skin cancer (squamous cell carcinoma) removed. The goal is to see if applying the therapy to the wound site can lower the chance of the cancer returning.…

This early-stage trial tests a new treatment for adults with a returning, aggressive brain cancer called glioblastoma. The therapy uses the patient's own immune cells, modified to recognize and attack the cancer, and delivers them directly into the brain. The main goals are to se…

This study compares three different programs to help pregnant women and new mothers maintain a healthy weight. About 795 participants will receive either usual care, a self-management program, or a community-based program. The goal is to see which approach best reduces weight gai…

This study looks at whether meals designed for specific ethnic groups (Asian Indian and Filipino) can improve blood sugar control in people with type 2 diabetes. Thirty participants will wear a continuous glucose monitor for one month while eating their usual diet and then specia…

This study tests whether injecting a man's own platelet-rich plasma (PRP) into his testicles can help him produce sperm. It includes 10 men who have already had a failed sperm retrieval procedure. The goal is to see if PRP can improve the chance of finding sperm for IVF.

This early-phase study tests a new treatment called B7-H3 CAR T cells for children and young adults whose solid tumors (like neuroblastoma or sarcoma) have come back or not responded to standard therapies. The treatment involves taking a patient's own immune cells, modifying them…

This study compares two surgical treatments for Fuchs endothelial dystrophy, a condition that clouds the cornea and blurs vision. Sixty adults will receive either a standard corneal transplant (DMEK) or a newer procedure that strips damaged cells and uses Ripasudil eye drops to h…

This study tests a special dye that makes brain tumor cells glow under a camera during surgery. The goal is to help surgeons see and remove more of the tumor while sparing healthy brain tissue. About 46 adults with malignant glioma or vestibular schwannoma will receive the dye be…

This study is testing whether a dye called panitumumab-IRDye800 can safely help surgeons see brain tumors more clearly during surgery in children and young adults aged 6 months to 25 years. The dye is given before surgery and makes tumor tissue glow under a special camera, helpin…

This study tests a special dye that attaches to lung cancer cells and makes them glow under a camera during surgery. The goal is to help surgeons see and remove all cancer, including tiny spots that might otherwise be missed. About 30 adults with lung cancer or lung metastases wi…

This study tests whether tranexamic acid (TXA), a drug that reduces bleeding, can prevent arthritis after an ACL tear. About 50 people aged 18-30 who recently tore their ACL will receive TXA or a placebo. Researchers will check joint inflammation and cartilage health using MRI an…

This study involves 600 adults having their first open-heart surgery. Doctors will use a temporary pacemaker to test if the heart is prone to atrial fibrillation (AFib) during the operation. Those who show risk will be randomly assigned to receive the drug amiodarone or standard …

This study tests a procedure called LYMPHA, done at the same time as breast cancer lymph node removal, to see if it can prevent lymphedema—a chronic, painful arm swelling. About 80 women having breast cancer surgery will be randomly assigned to receive LYMPHA or standard care. Re…

This study tests if people with knee osteoarthritis can learn to change how they use a calf muscle while walking, using gentle buzzes as feedback. The goal is to reduce stress on the knee joint. About 31 participants will try this training on a treadmill or over ground. Researche…

This study looks at the best way to clean wounds during surgery for advanced pilonidal disease. It compares standard saline to a special solution called hypochlorous acid to see which helps wounds close faster. About 72 people having surgery for stage 3 pilonidal disease will tak…

This study tests whether using virtual reality (VR) during physical therapy helps children with cancer be more active while in the hospital. About 40 kids and young adults aged 10 to 25 will try both VR-assisted and traditional physical therapy to see which one gets them moving m…

This study tests a new extended-release sodium oxybate taken as a single dose at bedtime for children with narcolepsy type 1. The goal is to see if children prefer this once-nightly option over current twice-nightly oxybate medicines, and to check its safety and how well it contr…

This study looks at whether a treatment called DTPA chelation can help people with Gadolinium Deposition Disease (GDD), a condition caused by gadolinium from MRI contrast dyes staying in the body. Researchers will give 50 adults at least five two-day treatment sessions and track …

This study tests whether injecting a long-lasting numbing medication (Exparel) into the side of the nose can reduce severe face and headache pain. About 15 adults with conditions like migraine or cluster headache will receive either the drug or a placebo, then switch groups. The …

This study tests whether a single online group class, called Empowered Relief, can help Spanish-speaking adults with chronic pain feel better. The class teaches pain relief skills and is delivered by video conference. Researchers will follow 110 participants for one month to see …

This study tests two simple early treatments—writing about the experience (Written Exposure Therapy) and guided breathing exercises (Capnometry Guided Breathing)—to see if they can reduce PTSD symptoms in new mothers after a traumatic childbirth. About 70 women who recently gave …

This study tests a virtual program where parents learn to help their autistic child cope with insistence on sameness behaviors, like needing routines or getting upset over changes. About 30 children aged 6 to 10 with autism and average intelligence will take part. The goal is to …

This pilot study at Stanford University is testing whether giving rTMS (a non-invasive brain stimulation) in the morning or evening works better for treating insomnia. Ten adults with insomnia will receive ten sessions over two weeks. Researchers will track sleep quality and brai…

This study tests whether adding a nerve stimulation device to standard medical care can better relieve chronic neuropathic pain in the lower back, pelvis, or legs. About 148 adults with this type of pain will be randomly assigned to either standard care alone or standard care plu…

This pilot study looks at whether a new wheeled mobility tool helps people move around more easily after total knee replacement. About 19 adults aged 18-99 who can walk with at most a cane or crutch before surgery will use the device. Researchers will track how much they use it a…

This study tests a new drain system (Interi) against standard drains in 20 women having implant-based breast reconstruction after mastectomy. The goal is to see if the new drain reduces complications, shortens drain time, and improves patient comfort. Participants must be 18-65, …

This study looks at two methods of delivering pain medicine through a nerve block catheter after surgery: a steady drip or scheduled small doses. Researchers want to see which method controls pain better and reduces the need for extra painkillers. About 240 adults having surgery …

This study tests a new type of spinal cord stimulation for people with long-lasting pelvic pain that hasn't improved with other treatments. The device automatically adjusts its energy based on real-time feedback to better target pain. Ten adults will be enrolled to see if it safe…

This study tests whether esomeprazole, a drug usually used for heartburn, can help improve social communication in young children with autism. Researchers will give the drug to 25 children aged 2 to 6 for 12 weeks and measure changes in social behavior. The goal is to see if this…

This study compares a combination of ibuprofen and acetaminophen to the opioid oxycodone for managing pain after thumb surgery (trapeziectomy) for osteoarthritis. About 121 adults will be randomly assigned to one of the two pain regimens and tracked for 30 days. The goal is to se…

This study compares two approaches to supportive cancer care for adults with cancer: one uses technology, the other a redesigned team-based model. About 3,000 newly diagnosed patients will join to see which approach better improves quality of life over 12 months. The goal is to f…

This study looks at whether the sleep supplement melatonin can help teens aged 12–18 recover from major bone or spine surgery by improving sleep quality. About 45 teens having surgery for conditions like scoliosis or hip problems will take melatonin or a placebo. The goal is to s…

This study tests a non-invasive 3D-printed external device to help men with erectile dysfunction achieve satisfactory sexual intercourse. Nine men with moderate to severe ED, along with their female partners, will try the device. The goal is to see if it is safe and improves erec…

This study tests whether a cardiac rehabilitation program can help adults with Fontan failure (a type of heart failure from a birth defect) walk more each day and feel less frail. About 50 participants will either join the rehab program or receive usual care. The goal is to see i…

This study tests whether a smartphone app that uses neurofeedback can help people with mild to moderate depression. Participants will use the app to learn about positive emotions and brain chemicals. The goal is to see if the app is safe and effective, and to prepare for a larger…

This study looks at whether using an aromatherapy inhaler (with lavender and peppermint) can help reduce distress and improve coping for patients who have had a stem cell transplant. About 50 adults will try the inhaler during their hospital stay. The goal is to see if this simpl…

This study tests whether adding insomnia treatment to standard suicide-focused therapy helps teens at high risk for suicide. About 44 teens aged 12-18 with insomnia and a history of self-harm will receive either dialectical behavior therapy alone or combined with digital cognitiv…

This study at Stanford University is testing whether simple stress reduction practices like breathing exercises (cyclic sighing, box breathing) and hypnosis can lower anxiety. Eighty adults will practice daily for four weeks. Researchers will measure changes in brain activity, he…

This study tests whether zolpidem, a sleep medication, can improve sleep in children and teens with autism. About 26 participants aged 8 to 17 will receive either the drug or a placebo for 8 weeks, then switch. The goal is to see if the drug helps with sleep quality and patterns.

This study tests a smart system that reads facial expressions during computer-based brain training to keep older adults engaged and motivated. The goal is to help people aged 60-89 who are at risk for Alzheimer's stick with at-home cognitive exercises. Researchers will compare tr…

This early study at Stanford tests whether rapid, non-invasive brain stimulation can reduce the urge to hoard. Ten adults with hoarding disorder will receive the treatment and report changes in their acquiring habits. The goal is to see if this safe, outpatient procedure can ease…

This study tests whether a device that sends gentle magnetic pulses (PEMF therapy) can reduce pain after knee or shoulder surgery. About 76 adults will either receive the real device or a placebo. Researchers will measure pain levels and painkiller use 10 days after surgery.

This study tests whether N-acetylcysteine (NAC), a well-tolerated nutritional supplement, can reduce restricted and repetitive behaviors in children with autism. About 144 children aged 3 to 12 will receive either NAC or a placebo for 12 weeks. Researchers will measure changes in…

This study tests a new device called the Blossom Smart Expander for women having breast reconstruction or augmentation. Instead of weekly needle injections to slowly stretch the skin, this device automatically fills with a tiny amount of saline over time. The goal is to see if it…

This study tests whether a proven sleep therapy (CBT-I) can change brain activity related to emotion regulation, helping ease depression and anxiety. About 120 adults with insomnia and depression will receive CBT-I and undergo brain scans. The goal is to see if improving sleep ca…

This early-stage study tests whether insulin eye drops are safe for people with glaucoma and other optic nerve conditions. Researchers will monitor 52 participants for side effects over 1-2 months. The goal is to see if this approach can be developed further to protect vision.

This study tests whether virtual reality (VR) field trips can improve the emotional well-being of children ages 5 to 17 who are staying in the hospital for at least one day. Using VR headsets, kids will visit famous wonders of the world and then do hands-on activities at their be…

This study tests whether having a dream while under anesthesia can reduce symptoms of PTSD. About 42 adults with PTSD will be randomly assigned to either deep sedation (to encourage dreaming) or light sedation (to avoid dreaming). Researchers will compare changes in PTSD symptoms…

This study looks at whether a 12-week early intervention program helps improve social communication in preschoolers (ages 2-5) with developmental disorders like autism or intellectual disability. Children attend either a center-based preschool or home sessions for 12 hours each w…

This study tests whether adding dextromethorphan (a cough suppressant) to fluoxetine (an antidepressant) can safely reduce symptoms of obsessive-compulsive disorder (OCD) and related conditions like body dysmorphic disorder. About 60 adults in California will take the combination…

This study tests whether using a virtual reality (VR) headset can make behavioral activation therapy more effective for older adults (65+) with major depression. Thirty participants will use VR to engage in activities that boost mood, and researchers will measure changes in depre…

This study looks at whether a 16-week therapy program called Pivotal Response Treatment (PRT) works better when done at a center or at home for young children with autism who have trouble speaking. About 120 children aged 2 to 5 will take part, and their progress will be compared…

This study tests whether Botox injections into the skin can reduce the number of painful attacks in people with trigeminal neuralgia, a severe facial pain condition. It includes 20 adults who have not gotten enough relief from medications or are not candidates for surgery. Partic…

This study tests whether diphenhydramine, a common allergy medicine that makes people sleepy, can improve sleep in children and teens with autism. About 26 participants aged 8 to 17 will receive either the drug or a placebo for several weeks, then switch. The goal is to see if it…

This study tests a non-invasive device that uses pulsed radiofrequency to treat chronic nerve pain after an injury or surgery. About 95 adults with long-lasting nerve pain will receive the treatment to see if it reduces pain. The goal is to find a safe, drug-free option for manag…

This study tests whether using local anesthesia (numbing the area) with sedation is as good as general anesthesia (being fully asleep) for 1-3 level lumbar decompression surgery. About 100 adults aged 40-95 with lumbar spinal stenosis will take part. Researchers will measure pain…

This study compares two online treatments for chronic pain: an 8-week cognitive behavioral therapy program (16 hours total) and a single 2-hour pain relief skills class. Researchers want to see which works better for reducing pain intensity and interference. The study will enroll…

This study tests whether targeted thigh-muscle exercises can improve knee function and movement in teenagers who have had ACL reconstruction surgery. Researchers will measure leg strength and jumping mechanics in 40 participants. The goal is to find better ways to help young athl…

This study tests whether a special 5-day diet that mimics fasting can lower inflammation and improve quality of life in people with mild to moderate ulcerative colitis. Participants will follow the diet for three cycles while researchers track symptom changes. The goal is to see …

This study tests whether suvorexant, a sleep medication, helps teenagers (13-17 years) with autism fall asleep faster and stay asleep longer. About 26 participants will receive either the drug or a placebo, then switch after a period. The goal is to see if it improves sleep quali…

This study compares two types of LASIK surgery—wavefront-guided and ray tracing-guided—to see which one improves vision more for people with nearsightedness and astigmatism. About 70 adults aged 22 and older with healthy eyes will have one type of LASIK in each eye. The goal is t…

This study tests how guanfacine, a medication typically used for blood pressure, affects brain networks and thinking problems in people with depression. Researchers will enroll 162 adults aged 18-60 who are currently experiencing a major depressive episode. The goal is to see if …

This study tests a non-surgical treatment for shoulder arthritis. It compares injections of a person's own processed fat tissue (MFAT) to standard steroid shots. The goal is to see if the fat injection reduces pain and improves shoulder function better than the usual treatment. A…

This study tests whether the medication pramipexole can ease depression symptoms by targeting specific brain circuits. About 60 adults with recent depression symptoms will take the drug for 8 weeks, then taper off over 2 weeks. Researchers use brain scans to see if certain circui…

This study compares the Gokhale Method posture therapy to standard physical therapy for people with chronic lower back pain. Researchers want to see which approach works better for reducing pain and improving daily function. The study involves 100 adults aged 18-65 with moderate …

This study tests a simpler way for paramedics to treat seizures in children. Instead of calculating doses, paramedics will use age-based, pre-set doses of a seizure-stopping medicine given as a shot or nasal spray. The goal is to see if this approach stops seizures before the chi…

This study tests a new group program called BEAR for women who have experienced trauma and currently have suicidal thoughts. The program combines psychological skills, education about trauma, and physical self-defense training. Researchers want to see if it's possible to run this…

This study tests a simple blood test (liquid biopsy) to see if it can tell which triple-negative breast cancer patients will benefit from the drug capecitabine after standard chemotherapy. About 40 adults with leftover cancer after chemo will give blood samples before and during …

This study is creating a simple tool to measure how well the body uses insulin and overall heart health in children and teens with severe obesity. Researchers will use data from fitness trackers and glucose monitors, along with blood tests, to understand how activity and blood su…

This study looks at whether a program called Food FARMacia is practical and well-liked by families who struggle to afford enough food. About 80 families with babies aged 6 to 18 months will get nutrition advice and regular food distributions. The goal is to see if this approach c…

This study is collecting medical information from 2,000 people with advanced mycosis fungoides or Sézary syndrome, rare types of skin lymphoma. The goal is to create a tool that helps doctors identify which patients are at higher or lower risk, so they can choose the best treatme…

This study is building a registry of people with gastric cancer, a family history of it, or a specific gene mutation (CDH1). Participants fill out online questionnaires and provide saliva, blood, or tissue samples. The goal is to learn more about what causes gastric cancer and ho…

This study aims to learn more about oropharyngeal carcinoma (a type of throat cancer) and its link to HPV. Researchers will collect blood samples from 1000 patients before treatment and at six follow-up visits, plus tumor tissue when available. The goal is to better understand th…

This study is testing a new method to collect and analyze cells and molecules from the uterus using a gentle wash during gynecologic surgery. Researchers will enroll 50 women to see what types of cells and genetic material can be found in the fluid. The goal is to learn more abou…

This study looks at how the flu vaccine works in people who have had COVID-19, including those with long-term symptoms or conditions like obesity and diabetes. Researchers will measure immune responses over time in 230 adults and children (ages 9-64) who had COVID-19, plus a cont…

This study aims to understand how ketamine causes dissociative symptoms—feelings of detachment from oneself or reality—in people with epilepsy. Researchers will give ketamine to 20 adults staying in Stanford's epilepsy monitoring unit and measure their dissociative experiences us…

This early-stage study at Stanford tests whether giving magnetic brain stimulation during sleep is safe and practical for people with major depression. Fifteen adults who have not gotten better with at least one antidepressant will receive both real and fake stimulation in separa…

This study aims to uncover the genes and proteins that drive head and neck cancer. Researchers at Stanford will analyze tissue from 500 patients undergoing surgery to better understand how the disease develops and progresses. The goal is to lay the groundwork for future diagnosti…

This study tests whether augmented or virtual reality (AR/VR) goggles can help doctors perform ultrasound-guided procedures, such as numbing nerves or placing lines, more accurately and comfortably. About 100 adults having these procedures will take part. The goal is to see if th…

This study at Stanford University will map the electrical signals in the hearts of 200 people with persistent atrial fibrillation (AF) who are scheduled for ablation or Maze surgery. The goal is to see if the size of organized heart regions can predict who will benefit most from …

This study tests whether hearing aids with built-in sensors and artificial intelligence can assess a person's risk of falling and help them hear better in noisy environments. Researchers at Stanford University will enroll 350 adults aged 55 and older who already wear hearing aids…

This study follows 600 adults aged 35–84 who are at higher risk for stomach cancer, including those with precancerous changes like intestinal metaplasia. Researchers collect tissue and blood samples during routine endoscopies to track how these changes progress or reverse over ti…

This study collects blood and tumor samples from up to 3,300 women at high genetic risk for breast, ovarian, or related cancers. Researchers aim to understand how these cancers develop and how treatments work. Participants include those with BRCA1/2 or other gene mutations, or st…

This study uses surveys and phone interviews to learn how COVID-19 impacts people with cancer. Researchers want to understand the challenges these patients face during the pandemic. About 50 adults with cancer will take part. No treatments or medications are involved.

This study aims to improve depression treatment by finding better ways to measure brain excitability. Researchers at Stanford will use a technique called TMS (transcranial magnetic stimulation) to stimulate the brain and record the brain's electrical responses. 145 adults with mo…

This study explores whether a non-invasive brain stimulation technique called theta burst stimulation can change brain activity in people with schizophrenia. Researchers will use TMS to target the hippocampus, a memory-related brain region, and measure changes with EEG. The goal …

This study is testing two experimental insulin formulas to see if they work faster than a current insulin (Lyumjev) in adults with type 1 diabetes. Twenty participants will receive each insulin after a meal, and blood samples will be taken to measure how quickly the insulin peaks…

This study collects tumor tissue from people with Hodgkin's or non-Hodgkin's lymphoma to learn more about the cancer cells. It does not test any new treatment. Participants must already be scheduled for a routine procedure to remove lymph nodes. The goal is to better understand t…

This study compares two types of pain medications (anti-convulsants and anti-depressants) in 450 adults with chronic pain. The goal is to see which works better in everyday patients, including those with other health issues often left out of traditional trials. Researchers will a…

This study from Stanford University aims to understand why people's blood sugar levels respond differently to the same foods. Researchers will use continuous glucose monitors (CGMs) in 100 healthy adults, people with prediabetes, and those with type 2 diabetes to track blood suga…

This study tests whether giving low-income families a basic income plus support from community health workers helps them use health and social services more and improves child development. About 2,400 English- or Spanish-speaking families with healthy newborns on Medicaid in San …

This study looks at three types of body scans—MRI, PET/MR, and PET/CT—to see which one finds tumors best in children and young adults with cancer. About 100 participants with solid tumors will have their scans compared. The goal is to improve how doctors detect and measure tumors…

This study tests a personalized mobile tool to help women with overactive bladder (OAB) start and stick with treatment. About 30 women will use the app to learn about their condition, track symptoms, and get support. The goal is to see if the tool improves bladder health knowledg…

This study tests whether a safe, non-invasive technique called caloric vestibular stimulation (using warm or cool water in the ear) can temporarily improve insight in people with obsessive-compulsive disorder, body dysmorphic disorder, or illness anxiety disorder. Researchers wil…

This study collects tissue and blood samples from people with stomach or esophageal cancer, as well as those at high inherited risk, to learn how genes and proteins contribute to these cancers. The goal is to better understand the disease, not to test a new treatment. About 100 p…

This study at Stanford University is looking for 130 adults with chronic low back pain and healthy volunteers. Researchers will use EEG (a non-invasive brain wave test) to see if patterns in the brain can predict how pain and thinking skills change over several months. The goal i…

This study looks at whether brain scans can help predict which young children with autism will improve the most with a behavioral therapy called Pivotal Response Treatment (PRT). The study involves 36 children aged 2 to 4 years old. Some children receive PRT right away, while oth…

This study looks at whether analyzing the DNA of a patient's tumor can help doctors recommend more effective treatments for metastatic cancer. Researchers will test tumor samples from 100 adults with advanced, incurable cancer to find genetic changes that match existing drugs or …

This study looks at how statins, a common cholesterol medicine, change bile acids and gut bacteria in people with primary sclerosing cholangitis (PSC), a serious liver disease with no cure. Researchers will collect samples from 15 adults with PSC to learn more about what causes t…

This study looks at how ketamine causes feelings of dissociation (feeling detached from yourself or reality). Researchers will give ketamine to 120 psychiatric inpatients and measure their dissociative symptoms using a standard scale. The goal is to understand the brain circuits …

This observational study at Stanford University looks at how levels of carotenoids (natural pigments from fruits and vegetables) in the skin relate to immune aging and skin health. Researchers will measure skin carotenoids and compare them with aging markers like wrinkles, inflam…

This study looks at how a single dose of N-acetylcysteine (NAC), a common supplement, changes brain chemistry in children with autism who have repetitive behaviors. Researchers will use brain scans and EEG to measure these changes. The goal is to understand why NAC might help red…

This study is looking at people with recessive dystrophic epidermolysis bullosa (RDEB), a genetic condition that causes painful blisters and wounds from minor bumps. Researchers at Stanford want to learn more about the disease and how patients' cells behave. The goal is to use th…

This study tests whether trained community health workers (called Promotores) can help Latino/a adults learn about mental health services and feel more comfortable seeking help. About 192 participants from specific San Jose zip codes will attend six educational sessions. The goal…

This study is a registry that collects contact information from people of all ages who are interested in joining future clinical trials for allergies or asthma. No treatments or tests are given—it simply helps researchers find volunteers for upcoming studies. Anyone from 0 to 100…

This study screens up to 1,000 people with possible food allergies to see if they qualify for future clinical trials at Stanford. Participants undergo food challenges and skin tests to confirm their allergies. The goal is to build a pool of diagnosed individuals ready for upcomin…

This study looks at proteins and other markers in the blood of 2000 people with or suspected of having cancer. The goal is to find markers that help doctors diagnose cancer, choose the right treatments, and predict if the cancer will come back. Participants must be 18 or older an…

This study looks at how teenagers and young adults (ages 15-29) with cancer prefer to be involved in decisions about their treatment. Researchers will use made-up scenarios to see if participants want an active, shared, or passive role. The goal is to understand what factors, lik…

This study at Stanford University is testing whether a computer program can help doctors predict which patients with atrial fibrillation (an irregular heartbeat) will benefit from a procedure called ablation. About 120 adults who are already scheduled for ablation will have their…

This study tests an online training course for parents of young children (ages 2 to 5) with autism. The course teaches parents a therapy called Pivotal Response Treatment (PRT) to help improve their child's communication. Researchers will check if parents learn the therapy well a…

This study looks at how ketamine affects the brain to reduce symptoms of obsessive-compulsive disorder (OCD). Researchers will measure changes in OCD severity using a standard scale. The study involves 150 adults aged 18-65 with OCD who have not responded to at least one standard…

This study explores whether a motion-capture system that turns physical therapy into a game is easy to use and helpful for children aged 6-17 who are staying in the hospital. The goal is to see if this tool can encourage more movement and make therapy more engaging. The study wil…

This study follows 800 children who have had a stem cell transplant to collect health information and tissue samples over time. The goal is to better understand their long-term health and find ways to prevent or treat future problems. Participants are seen at Stanford's Lucile Pa…

This study compares different computer programs that help doctors see where abnormal heart signals start in people with atrial fibrillation. Researchers will look at heart structure images and electrical recordings from 1,000 adults who are already scheduled for a procedure calle…

This study tests a parent coaching program for parents of teens (ages 12-18) hospitalized for suicidal thoughts, suicide attempts, or self-harm. Some parents receive coaching on safety planning and parenting skills, while others get the usual hospital support. The goal is to see …

This study explores whether data from smartphones and smartwatches can help identify teens and young adults with cancer who are struggling emotionally. About 25 participants aged 10-25 will use an app and wearable device for two months. The goal is to see if this digital approach…

This study aims to create a digital decision-making aid for older adults with heart failure who are considering getting an implantable cardioverter-defibrillator (ICD). The tool will help patients weigh the benefits of preventing sudden cardiac death against the downsides of the …

This study from Stanford University aims to better understand allergies by looking at genetic, cellular, and physical changes in people with possible allergies. Researchers will enroll up to 2,500 participants to improve how allergies are diagnosed. The study involves skin testin…

This study aims to understand how a treatment called transcranial magnetic stimulation (TMS) changes brain activity. TMS is used for depression, but it doesn't work for everyone. Researchers will record brain signals from 49 adults with epilepsy or depression to find markers that…

This study is a registry that follows adults who are having a small device called an IVC filter placed or removed to prevent blood clots. Researchers will review medical records to see how patients do over time. The goal is to learn more about the safety and long-term effects of …

This study tests a web-based program for romantic partners who are worried about their loved one's drinking. Researchers will use daily surveys from both partners to build personalized feedback that helps the concerned partner communicate better and motivate change. The goal is t…

This study looks at embryos that were found to have extra or missing chromosomes (aneuploidy) or a mix of normal and abnormal cells (mosaicism) during genetic testing. Researchers want to see how often these embryos lead to a healthy baby and whether the pregnancy or child has an…

This study compares an AI platform to human experts in evaluating how well anesthesiology trainees communicate when disclosing a medical error. About 45 residents and fellows will participate in a simulated conversation, and their communication skills will be scored by both the A…

This study looks at how ultra-processed foods (like sugary drinks and snacks) affect brain areas linked to reward, attention, and memory in teenagers aged 13-15. Researchers will use brain scans and food-tasting tasks to compare responses to processed versus minimally processed f…

This study looks at how a 12-week exercise program changes proteins in the blood of people with heart failure. Researchers want to find which proteins improve with exercise, so they can eventually create a medicine that mimics those benefits. About 90 adults with heart failure wi…

This study follows 500 children and young adults (up to age 26) with B-cell leukemia or lymphoma who have received immunotherapy like blinatumomab or Kymriah. The goal is to learn about their long-term survival, remission, and any unmet needs they face. No new treatments are give…

This Stanford study follows 20 young women for 28 days to see how sleep, body rhythms, and the menstrual cycle work together and affect injury risk. Participants wear monitors to track movement, heart rate, and sleep. The goal is to understand these connections, not to test a tre…