Engineered immune cells take on deadly childhood brain cancer

NCT ID NCT04196413

First seen Nov 20, 2025 · Last updated Apr 28, 2026 · Updated 15 times

Summary

This early-stage trial tests whether specially engineered immune cells (GD2CART) can be safely made and given to children and adults with a rare, aggressive brain or spinal cord tumor called H3K27M-mutant diffuse midline glioma. The study aims to see if the cells can be produced successfully and to find the safest dose. Participants must have already received standard radiation therapy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Lucile Packard Children's Hospital (LPCH)

    RECRUITING

    Stanford, California, 94304, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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Conditions

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