Stanford University

This study follows 1,500 people with blocked heart arteries who were randomly assigned to get either stents or bypass surgery. Researchers will compare survival and quality of life after 10 years to see which treatment works better long-term. The goal is to help doctors and patie…

This study tests an experimental pill, VK 2019, that blocks a protein the Epstein-Barr virus uses to grow cancer cells. It is for people with nasopharyngeal cancer or other EBV-related cancers that have come back or spread and have no standard treatments left. The main goal is to…

This study tests a tiny implant that releases cells to protect the optic nerve in people with glaucoma. 54 participants receive either the implant or a sham procedure. The main goal is to see if it slows vision loss over 6 months. This is an early-phase trial, so the focus is on …

This study looks at whether a single dose of antibiotics given during nose surgery works just as well as taking antibiotics for several days after surgery to prevent infections. About 864 adults having nose surgery will be randomly assigned to one of two groups. The goal is to fi…

This study tests the drug pembrolizumab (Keytruda) in 12 people with advanced anaplastic thyroid cancer that cannot be cured by standard treatments. The goal is to see if the drug can shrink tumors or stop them from growing. Participants receive the drug every 3 weeks until the c…

This study tests whether a special cell implant placed in the eye can slow vision loss from glaucoma. Thirty adults with moderate to advanced glaucoma will receive either the implant or a sham procedure. The main goal is to see if the implant safely preserves visual field over 12…

This study compares two types of corneal transplant surgery (UT-DSAEK and DMEK) in 160 people with Fuchs dystrophy, a condition that clouds the cornea. It also tests whether a drug called rho-kinase inhibitor can reduce loss of important eye cells after surgery. The goal is to fi…

This study tests whether offering financial rewards can help people with schizophrenia, bipolar disorder, or substance use disorder stick to their long-acting injectable medication after being forced into the hospital. About 1,000 participants will be randomly assigned to receive…

This study tests whether a device that delivers gentle electrical stimulation to the eyes, used at home, can safely slow vision loss from open-angle glaucoma. About 45 adults with moderate vision damage will use the device regularly. The goal is to see if it protects the optic ne…

This early-stage trial tests whether giving specially engineered donor immune cells (CAR T cells) after a stem cell transplant is safe for adults with a high-risk type of B-cell leukemia. About 22 participants will receive the treatment to see if it can help prevent the cancer fr…

This study tests a topical cream called clascoterone for acne caused by testosterone therapy in transgender males. About 18 participants will use the cream daily for 3 months to see if it reduces acne without affecting their hormone levels. The goal is to provide a safe acne trea…

This study looks at whether remotely monitoring continuous glucose monitor (CGM) data can improve diabetes management in children within the first year after diagnosis. About 100 kids and teens newly diagnosed with type 1 diabetes will have their CGM data shared with their care t…

This early-phase study tests whether adding a short course of the drug dasatinib can make CAR T-cell therapy more manageable for adults with relapsed or refractory B-cell acute lymphoblastic leukemia. Eight participants receive dasatinib pills for three days each week during the …

This study was designed to compare two ways to treat walled-off necrosis (a pocket of dead tissue) caused by severe pancreatitis. One method uses a scope through the mouth to clean out the pocket, the other uses surgery through the stomach. The goal was to see which approach work…

This study tests a special nail made from a material that the body absorbs over time to treat a type of knee fracture called subchondral insufficiency. The nail is placed in the bone to help it heal and reduce pain. Ten people with knee pain lasting at least 3 months who are alre…

This study tests whether giving heated chemotherapy directly into the abdomen during surgery can help prevent uterine leiomyosarcoma from returning. Seventeen adults with recurrent cancer are receiving this treatment followed by standard chemo. The goal is to see if this approach…

This early-phase study tests a stem cell transplant method for people with advanced blood cancers like leukemia. Instead of using strong drugs to prevent complications, doctors add special immune cells (regulatory T-cells) to the donor cells to reduce the risk of graft-versus-hos…

This study tests whether a short course of radiation (1 to 5 days) after lumpectomy is as safe and effective as the standard 6.5-week whole-breast radiation. It includes women aged 40 and older with small breast tumors. The goal is to reduce treatment time while keeping cancer fr…

This study tests whether a nerve block in the neck can increase blood flow to the brain in people who develop narrowed blood vessels after a bleeding stroke. Ten adults in the ICU will receive the block, and researchers will measure changes in blood flow and neurological function…

This study tests an experimental drug called QBS72S in 21 adults with breast or lung cancer that has spread to the brain or the lining around the brain. The goal is to see if the drug can shrink brain tumors and help people live longer without the cancer getting worse. Participan…

This early-stage trial tests a treatment that uses a patient's own immune cells, modified to recognize and attack cancer cells, for adults with B-cell blood cancers that have returned or not responded to standard therapy. The study combines these modified cells with chemotherapy …

This study tests a type of radiation called high-dose brachytherapy for men with prostate cancer that hasn't spread. Doctors place tiny radioactive sources directly into the prostate to deliver a strong dose to the tumor while sparing nearby healthy tissue. The goal is to control…

This study tests two remote programs to help inactive older women become more physically active. About 232 women across the U.S. will use a step counter and smartphone tools to track and increase their daily steps. The goal is to see if combining a citizen science approach with a…

This early-stage study is testing a radioactive imaging agent called [18F]-C-SNAT4 to see how it travels through the body and whether it can help detect lung cancer on PET scans. About 20 healthy volunteers and people with lung cancer will receive the tracer and undergo scans. Th…

This early-stage study tests a radioactive imaging agent called 111In-panitumumab to see if it can safely find cancer spread to lymph nodes in people with head and neck cancer. About 28 participants will receive the agent before surgery, and researchers will compare its accuracy …

This study tests if replacing dirt floors with concrete in rural Bangladeshi homes can prevent gut infections in children. Researchers will follow 800 families, checking babies for parasites and diarrhea from birth to age 2. If concrete floors reduce infections, it could be a sim…

This study tests whether encouraging water instead of sugary drinks at childcare centers can help prevent obesity in young children. Researchers will track 882 preschool kids to see if the program changes their drink choices and weight over time. The goal is to find a simple way …

This study planned to use online tools like ads and social media to encourage people to avoid risky behaviors such as indoor tanning, with the goal of preventing skin cancer. It was designed for adult men on Facebook who showed interest in the LGBT community. However, the study w…

This study tests a free online program called Healthy Futures: Alternative-to-Suspension, designed to teach high school students about the risks of tobacco and nicotine and provide resources to quit. About 2,540 students from schools that agree to use the program or continue thei…

This study tests a quick, non-invasive brain stimulation method called accelerated intermittent theta-burst stimulation (aiTBS) to see if it can improve mood in people with borderline personality disorder (BPD) who are also experiencing a major depressive episode. About 45 adults…

This study tests whether a physical activity program can improve mood and reduce stress in pregnant people who have symptoms of depression or anxiety. About 88 participants will be randomly assigned to either the exercise program or usual care. The main goal is to see if the prog…

This study tests whether virtual reality (VR) therapy can help reduce depression in pregnant women who are hospitalized for complications. About 44 participants will either receive VR-enhanced behavioral activation therapy or standard social work support for 3 weeks. The goal is …

This study looks at whether a special pain relief skills session (called Empowered Relief) and educational videos can improve recovery for women after a cesarean delivery. About 60 women will take part, and researchers will measure how many sign up and attend the session, how sat…

This study tests whether a computer-based AI tool can teach glaucoma patients how to take a visual field test more accurately. The test checks side vision, which is important for monitoring glaucoma. If the tool works, it could lead to more reliable results, fewer repeat visits, …

This study tests whether listening to spatial audio (a 3D sound experience) can help healthy adults tolerate heat pain better. Participants will have heat applied to their skin and rate their pain with and without the audio. The goal is to see if this non-invasive technique can e…

This study is testing a new device that uses gentle vibrations on the belly, back, or temples to help people with chronic pain conditions like pelvic pain, abdominal pain, low back pain, or migraine. About 50 adults will try the real device or a placebo to see if it safely reduce…

This study compares two pain management methods for people with broken ribs: a continuous IV lidocaine infusion (current standard) and a newer nerve block called the erector spinae plane block (ESPB). The goal is to see which provides better pain control and helps patients breath…

This study tests whether a special silicone dressing (Neodyne embrace) can improve the appearance of abdominal scars in women who had breast reconstruction using tissue from their belly. Thirty women will have half their scar treated with the dressing and the other half left untr…

This study compares two types of spinal cord stimulation—high frequency and burst—to see which provides better long-term pain relief for people with chronic back or leg pain. About 7 adults who are candidates for spinal cord stimulation will be randomly assigned to one of the two…

This study looks at whether a home-based, virtually supervised exercise program can improve physical function in adults waiting for a kidney transplant. About 80 participants will either do the exercise program or receive health education. The main goal is to see if they can stan…

This study tests whether adding a blood flow restriction cuff to low-weight hand exercises can help people with ulnar-sided wrist pain recover faster. About 90 adults will do hand therapy with or without the cuff. The goal is to see if the cuff improves grip strength and reduces …

This study looks at whether N-acetylcysteine (NAC), a well-tolerated nutritional supplement, can reduce restricted and repetitive behaviors in children with autism spectrum disorder. About 144 children who previously took part in related NAC trials will receive the supplement and…

This study aimed to see if a new type of airway device could prevent dangerous drops in oxygen levels during anesthesia in patients at high risk, such as those with obesity or sleep apnea. The device was compared to a standard oral airway. However, the study was withdrawn before …

This study aimed to see if putting up fake windows that show outdoor scenes could improve the mood of teachers working in classrooms without real windows. It was planned for teachers at one school in New York, but the study was withdrawn before any teachers joined. No results are…

This study tests a virtual behavioral program for people with chronic migraine. Researchers want to find the best combination of techniques and see if letting patients choose their treatment helps. The goal is to reduce migraine frequency and intensity.

This study tests a mobile app designed to help people with long-term low back pain improve their quality of life and reduce symptoms. Up to 500,000 adults who own an iPhone and have had back pain for at least 6 months can join. The app tracks pain, activity, and movement, and pro…

This study tests a small vibrating device held near the skin during needle sticks (like IVs or blood draws) to see if it lowers pain and anxiety. About 1,100 children and adults will take part. Researchers will watch and ask about discomfort to see if the buzz helps people feel c…

This study tests whether a one-time pain relief skills session, called Empowered Relief, can lower the chance of long-term pain after a C-section. About 60 women who still have moderate to severe pain 6 weeks after delivery will take part. Researchers will check how many sign up …

This study aimed to see if having a parent appear on a video call during anesthesia induction could reduce children's anxiety as effectively as the sedative midazolam. It was designed for children aged 4 to 8 undergoing outpatient surgery. However, the study was withdrawn before …

This study tests a special audio-visual system called AVATAR to help children aged 3 to 10 stay still during radiotherapy without needing anesthesia. The goal is to see how many kids can complete at least one treatment session without anesthesia. If successful, this could make tr…

This study tests whether a nurse-led support program can improve symptoms, quality of life, and care planning for people with mild cognitive impairment or dementia living at home. About 200 participants and their caregivers will be assigned to either the nurse support program or …

This small study tested whether a non-invasive brain stimulation technique called tDCS can be used safely at home to reduce seizures in people with epilepsy. Four adults with hard-to-control seizures used the device daily for several weeks. Researchers tracked seizure counts, sev…

This study looked at whether a bioactive fabric sleeve can reduce arm soreness in college baseball players after pitching. Thirteen players from Stanford wore the sleeve and rated their soreness the next day. The goal was to see if the sleeve helps muscles recover better than a r…

This study aimed to see if adding nitrous oxide (laughing gas) to standard sedation during GI endoscopy (like colonoscopy) could reduce side effects such as fatigue, mental fogginess, and nausea after the procedure. The study was designed for adults 18 and older undergoing these …

This study compares a single dose of ketamine to a placebo (saline) given during sedation with propofol in 40 adults who have both chronic pain and depression. The goal is to see if the placebo works just as well as ketamine under these conditions. Participants will be sedated, r…

This study tests whether focused ultrasound to the brain can change how the anesthetic propofol works. Ten healthy adults will receive both real and fake ultrasound while under sedation. Researchers will measure brain signals and response times to see if ultrasound alters anesthe…

This study was designed to identify what causes sudden, severe pain flare-ups in children with Complex Regional Pain Syndrome (CRPS). Researchers planned to track changes in pain, diet, and environment. However, the study was withdrawn before any children were enrolled, so no res…

This study looks at how eating fermented and fiber-rich foods during pregnancy changes the gut bacteria of mothers and their babies. Researchers will track 135 pregnant women and their infants to see if diet affects the types of bacteria passed from mom to baby. The goal is to le…

This study tests whether an AI voice assistant can accurately capture health information reported by heart failure patients. About 100 adults with heart failure will use the tool to share their symptoms and well-being. Researchers will compare the AI's summaries to expert-reviewe…

This study tests whether advanced CT imaging can help doctors plan better coronary artery bypass surgery. About 200 adults with blocked heart arteries will get CT scans before and after surgery to measure blood flow and check for graft blockages. The goal is to improve surgical s…

This study looks at 600 adults with non-compaction cardiomyopathy, a rare heart muscle condition that can lead to heart failure, stroke, or dangerous heart rhythms. Researchers will use heart scans, genetic tests, and health records to find better ways to predict who is at highes…

This study looks at whether using a mild electrical current (neurostimulation) along with ultrasound can make nerve blocks work better for people having arm surgery. About 82 adults will be enrolled to see if the stimulation speeds up numbness and muscle relaxation. The goal is t…

This study aimed to test a new PET camera designed specifically for breast imaging, with very high detail. The goal was to see if the camera could produce clear images and to learn about using it in a real clinic. However, the study was withdrawn before any participants were enro…

This study tests whether special ultrasound scans can detect early changes in tumor blood flow that show if cancer immunotherapy is working. About 30 adults with solid tumors will get scans before and after 3 weeks of treatment. The goal is to see if these scans can predict treat…

This study aimed to see if stroke patients could use an augmented reality (AR) program at home for arm rehabilitation. Researchers planned to track how often patients completed their 30-minute sessions over 8 weeks. However, the study was withdrawn before any participants were en…

This study involves 100 veterans with depression that hasn't improved with medication. Researchers use brain scans to see if certain brain activity patterns can predict who will benefit from transcranial magnetic stimulation (TMS), a non-invasive treatment that uses magnetic puls…

This study aimed to compare how much the bicep tendon moves after surgery using either one standard anchor or two mini anchors. Participants would have had a small marker placed on the tendon and X-rays taken right after surgery, at 2 weeks, and at 6 months. However, the study wa…

This study looks at whether giving pharmacists extra education and feedback helps them better manage heart failure medications for veterans. About 400 veterans and their care teams at 22 VA sites will take part. The goal is to see if these strategies increase the number of times …

This study aimed to see if telling patients and their doctors about calcium buildup in heart arteries (found on lung cancer scans) would lower the chance of death, heart attack, or stroke. It was designed for adults without known heart disease who had a lung scan showing signific…

This study looks at how fentanyl changes brain activity using EEG (a brain wave test) in 20 adults having surgery. Researchers want to find a specific brain signal linked to fentanyl and see if it relates to how much people like the drug. No new treatment is tested—only brain pat…

This study was designed to learn why children with type 1 diabetes who have public insurance often don't use diabetes technology like continuous glucose monitors. Researchers planned to interview and survey healthcare providers to find out what helps or hinders technology use. Th…

This study aims to create a mobile app that automatically scores physical and cognitive tests for older adults, helping to detect early signs of Alzheimer's disease. Researchers will collect video data from 20-30 healthy adults aged 18+ to develop and refine the app. The goal is …

This study aimed to find out if removing the nail plate helps people with nailbed injuries heal better. It planned to track complications, pain, appearance, and hand function over time. However, the study was withdrawn before enrolling any participants, so no results are availabl…

This study looks at how two different exercise programs—high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT)—affect the health of 135 healthy but inactive adults. Over 12 weeks, researchers will measure changes in fitness, muscle strength, bod…

This study aimed to see if artificial intelligence simulations could help anesthesiology trainees improve their communication skills for difficult talks, like telling a patient about a medical mistake. It was designed for healthcare workers at one hospital, but the study was with…

This study tests whether artificial intelligence (AI) can help medical interns learn how to use ultrasound machines more quickly and accurately. About 150 internal medicine residents will be split into two groups: one group uses a handheld ultrasound device with AI assistance, th…

This study is creating a large database of information from 250 older adults (65+) having surgery with general anesthesia. Researchers collect blood samples, brain wave recordings, and memory tests before and up to a year after surgery. The goal is to find patterns that could hel…

This study tests whether a digital symptom questionnaire, called Ped-PRO-CTCAE, can be used by children and teens with cancer (ages 7-21) and their caregivers during clinic visits. The tool is shared with doctors to see if it's practical, easy to use, and helpful. About 85 partic…

This study aimed to see if a fast-acting form of brain stimulation (called accelerated TMS) could change brain activity linked to suicidal thinking in adults hospitalized for major depression. The researchers planned to measure changes in suicidal thoughts using a standard questi…

This study looks at whether fixing sleep problems can help with mood and behavior issues like anxiety, agitation, and depression in people with early Alzheimer's or mild cognitive impairment. About 150 adults aged 50-90 with sleep troubles and mild mood symptoms will get either a…

This research study collects blood, tumor tissue, and other body fluids from 1,000 adults with lung cancer, thymus cancer, or mesothelioma. The goal is to analyze these samples to find biological markers that could predict how the disease will progress or which treatments might w…

This study collects tissue samples from people receiving bone marrow transplants and their donors. Researchers will analyze genes and proteins to learn what causes cancer to develop and progress. The goal is to improve future transplant outcomes and reduce complications.

This study aimed to see if a mobile monitoring tool could accurately identify surgical site infections (SSIs) in orthopedic surgery patients, compared to the usual manual review. The study was withdrawn before enrolling any participants, so no results are available. It was design…

This study looks at how much patients like medications they receive before and during medical procedures. Researchers will ask 130 participants to rate their drug liking and measure brain activity with EEG. The goal is to understand how these drugs affect feelings of pleasure or …

This study follows 275 teens aged 11-18 with chronic muscle or joint pain to find clues that predict who will get better and who will have lasting pain. Researchers measure pain levels and daily function over time. The goal is to improve treatment by identifying early markers of …

This study tests whether digital programs can improve the health, wellbeing, and daily functioning of people recently diagnosed with cancer. About 440 participants will be randomly assigned to one of two online courses, complete questionnaires, and provide blood samples at home. …

This study aims to identify brain-based subtypes of Obsessive-Compulsive Disorder (OCD) and see how they respond to two different targets of repetitive transcranial magnetic stimulation (rTMS). Researchers will use brain scans to measure connectivity in specific networks before a…

This study aimed to help 4th graders develop healthy bladder habits through education, water stations, and changes to bathroom policies. It was withdrawn before enrolling any participants, so no results are available. The goal was to understand and improve bathroom use and reduce…

This study looks at whether a special type of imaging scan (DMI) can help predict how well a new drug (BPM31510) works in people with glioblastoma, an aggressive brain cancer. The study was planned for 10 participants but is currently on hold. The goal is to see if the scan can f…

This study looks at how two parts of the thalamus (ANT and PLV) are connected to other brain areas and how they are involved in seizures and memory. Researchers will record brain activity from 100 epilepsy patients who already have electrodes implanted for medical reasons. The go…

This study at Stanford University is testing whether wearable devices can help measure fatigue, sleep, and daily activity in people with primary biliary cholangitis (PBC). About 30 participants will wear a device and answer questionnaires to see if changes in body data match chan…

This study aimed to see if notifying patients and their primary care doctors about calcium buildup in heart arteries (found on a prior chest CT) would increase the number of people starting cholesterol-lowering statins. It planned to include adults aged 18-84 with moderate to sev…

This study tests a program called Tap Trust that aims to help families feel better about their home tap water. Researchers want to see if it increases how much water preschool-aged children and their parents drink. About 100 families are taking part.

This study tests a web-based decision aid and planning tool for female cancer survivors who want to have children in the future. About 260 participants who have completed cancer treatment will use the tool to help them make informed choices about family building. The goal is to s…

This study looks at whether a parent coaching and family navigation program (Project AFECT) can help families right after a child is diagnosed with autism. About 200 parents of children aged 1 to 5, who are Hispanic/Latino, Black/African-American, or have Medi-Cal insurance, will…

This study tests whether a custom AI chatbot can help cataract patients better understand their artificial lens choices before meeting their surgeon. About 70 adults will either get standard counseling or standard counseling plus an AI explanation. The goal is to see if the AI to…

This study tests whether cameras and sensors placed in the home can automatically track changes in mood, behavior, and daily activities in older adults. Researchers will compare this data with standard questionnaires to see if it helps detect early signs of memory loss or dementi…

This study aimed to see if anesthesiology residents in Hong Kong could use augmented reality (AR) to practice crisis skills with experts in the United States. The focus was on non-technical skills like teamwork and decision-making. However, the study was withdrawn before any part…

This study looks at whether giving non-alcoholic beers to people being treated for alcohol use disorder is acceptable and practical. About 60 adults in California who are already in a treatment program will receive non-alcoholic beers for 6 weeks. Researchers will measure satisfa…

This early-stage study at Stanford University compares ketamine to a placebo (saline) during sedation in 15 healthy adults with major depressive disorder. The goal is to see how these drugs affect brain activity and experiences like dreams or thoughts. Researchers will use EEG to…

This study aims to find biological markers that can tell if a person with long-term muscle or joint pain will recover or develop lasting disability. Researchers will follow 250 adults to measure pain interference and identify patterns linked to recovery. The goal is to improve di…

This study aimed to see if personalized lifestyle coaching could help emergency medicine residents stay alert and perform better during night shifts. It planned to track sleep, reaction time, and mood using an iPhone app and a Fitbit. However, the study was withdrawn before enrol…

This study looks at how immune cells in different types of body fat (belly fat vs. fat under the skin) are linked to insulin resistance, a condition where the body doesn't use insulin well. Researchers will analyze fat samples from 50 people having weight-loss surgery to see if c…

This study aimed to understand how the mindsets of newly diagnosed cancer patients influence their physical and mental health during treatment. Researchers planned to follow patients from diagnosis through six weeks after treatment and test a brief mindset intervention. However, …