Scientists probe Fat's secret role in diabetes risk
NCT ID NCT04708535
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how immune cells in different types of body fat (belly fat vs. fat under the skin) are linked to insulin resistance, a condition where the body doesn't use insulin well. Researchers will analyze fat samples from 50 people having weight-loss surgery to see if certain immune cell patterns affect weight loss success. The goal is to better understand why obesity leads to health problems, not to test a treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2017
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
There are no restrictions in regards to gender, race, or socioeconomic status. The racial/ ethnic composition of the study population will be reflective of the communities surrounding the Stanford University Medical Center.
- Ages
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30 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Current patients of Stanford Healthcare, Bariatric Surgery Clinic, scheduled to undergo bariatric surgery (sleeve or RYGB) * BMI 30-55kg/m2 * 30-65 years of age * good general health, no major organ disease * non-diabetic by current American Diabetes Association (ADA) criteria (fasting glucose \<126mg/dl) Exclusion Criteria: * Subjects with any clinical or biochemical evidence of significant anemia, gastrointestinal, cardiac, hepatic or renal disease will be excluded. * Subjects with other medical problems may participate as long as the problems are stable. * Subjects with active psychiatric disorders or past history of bariatric surgery * Pregnant or lactating women will also be excluded from the study, due to possible risk to the fetus or infant.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Stanford University
Stanford, California, 94305, United States
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