Could breast cancer radiation be cut from weeks to days?

NCT ID NCT00185744

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study is testing whether shorter, more focused radiation treatments after lumpectomy are as safe and effective as the standard six-and-a-half-week course. About 121 women with early-stage breast cancer are receiving one of several accelerated radiation methods, including a single dose during surgery or five-day treatments. Researchers are tracking cancer recurrence, side effects, and cosmetic outcomes through 2029.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Radiation therapy (intra-operative, brachytherapy, external beam, or stereotactic)
What this could lead to
If successful, this could offer women with early-stage breast cancer a much shorter radiation course after lumpectomy, reducing treatment time from weeks to days.
What could go wrong
This is an early-stage study with no phase designation, and results are not yet final. Shorter radiation may not be as effective as standard whole-breast radiation in preventing cancer return.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Stanford University School of Medicine

    Stanford, California, 94305, United States

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