Stanford study pits HIIT against moderate exercise to see which is healthier

NCT ID NCT05513300

Ongoing Knowledge-focused Sponsor: Stanford University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Stanford study compares high-intensity interval training (HIIT) with moderate-intensity continuous training (MICT) in 135 healthy but sedentary adults. Over 12 weeks, participants will exercise three times a week for about an hour. Researchers will measure changes in fitness, muscle strength, body composition, and molecular markers like genes and proteins to see which type of exercise leads to better health outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: exercise training (high-intensity interval training or moderate-intensity continuous training)
What this could lead to: If successful, this study could help clarify which type of exercise is better for improving fitness and health at the molecular level.
What could go wrong: This is an early-stage observational study with no treatment for a disease. Results may not apply to people who are not healthy or sedentary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Sedentary Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LIFESTYLE SEDENTARY

Contacts and locations

Locations

Stanford University

Stanford, California, 94305-2200, United States

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