Brain zaps for BPD depression: new hope or hype?

NCT ID NCT04870255

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a quick, non-invasive brain stimulation method called accelerated intermittent theta-burst stimulation (aiTBS) to see if it can improve mood in people with borderline personality disorder (BPD) who are also experiencing a major depressive episode. About 45 adults will receive either real or fake (sham) stimulation to compare effects. The goal is to measure changes in depression severity using a standard rating scale.

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Conditions

The condition(s) this trial relates to.

bipolar II disorder borderline personality disorder Depression major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Stanford Hospital

    Stanford, California, 94305, United States