BORDERLINE PERSONALITY DISORDER
Clinical trials for BORDERLINE PERSONALITY DISORDER explained in plain language.
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Scientists test mind training to tame emotional storms in borderline patients
Disease control Recruiting nowThis study is testing a new training program that teaches people with borderline personality disorder (BPD) how to better manage their intense emotions. Researchers will work with 130 participants to see if learning specific thinking strategies can change brain activity and reduc…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Personal videos could help teens manage severe emotional struggles
Disease control Recruiting nowThis study is testing whether a special group therapy program can help teenagers manage symptoms of borderline personality disorder. The program lasts about one year and includes group sessions, individual meetings, and parent support. Researchers will compare teens in this progr…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Turku University Hospital • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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New couples therapy offers hope for BPD and relationship healing
Disease control Recruiting nowThis study is testing a new 12-session couples therapy called Sage for people with borderline personality disorder (BPD) and their partners. It aims to reduce BPD symptoms, improve relationship conflict, and support the partner's mental health. Researchers will compare Sage to st…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: PHASE2 • Sponsor: York University • Aim: Disease control
Last updated Mar 25, 2026 14:07 UTC
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Eye movement therapy trial offers hope for borderline personality disorder
Disease control Recruiting nowThis study is testing whether EMDR therapy, commonly used for trauma, can help reduce the core symptoms of borderline personality disorder. Researchers will work with 56 adults diagnosed with BPD, some of whom also have PTSD. The goal is to see if this short-term therapy can impr…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia • Aim: Disease control
Last updated Mar 24, 2026 12:01 UTC
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10-Week therapy aims to tame impulsivity in severe personality disorder
Disease control Recruiting nowThis study is testing a new 10-week therapy program called SINTYA for young adults (16-25 years old) with severe borderline personality disorder. The program includes weekly group and individual sessions designed to help manage impulsive behaviors, emotional difficulties, and red…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Brain zaps target emotional control center in BPD trial
Disease control Recruiting nowThis UCLA study is testing whether targeted magnetic brain stimulation can help people with Borderline Personality Disorder better manage their emotions and reduce impulsive behaviors. The research will involve 30 participants who will receive either real or placebo brain stimula…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: University of California, Los Angeles • Aim: Disease control
Last updated Mar 02, 2026 15:21 UTC
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Zap your brain to calm down? new study tests quick fix for emotional distress
Symptom relief Recruiting nowThis study is testing whether a single session combining a non-invasive brain stimulation technique (rTMS) with training in emotion regulation skills can help people who struggle to calm down when upset. Researchers want to see if this combined approach changes brain activity and…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Duke University • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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Party drug tested as social therapy for personality disorder
Symptom relief Recruiting nowThis Yale University study is testing whether a single dose of MDMA (commonly known as ecstasy) can help adults with Borderline Personality Disorder better understand social situations and recognize emotions in others. Researchers will measure changes in sociability and emotional…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: PHASE2 • Sponsor: Yale University • Aim: Symptom relief
Last updated Mar 30, 2026 14:31 UTC
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Brain scans teach patients to cool their emotional storms
Symptom relief Recruiting nowThis study is testing a brain training method to help people with borderline personality disorder manage their intense, unstable emotions. Participants will learn to control activity in a key emotion-processing brain area (the amygdala) using real-time feedback from MRI scans. Th…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: PHASE1, PHASE2 • Sponsor: Central Institute of Mental Health, Mannheim • Aim: Symptom relief
Last updated Mar 16, 2026 15:24 UTC
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Zap to the head? study tests brain stimulation for common mental health struggles
Knowledge-focused Recruiting nowThis study aims to understand if a mild, non-invasive brain stimulation technique can improve thinking skills like memory, focus, and decision-making. It will involve 600 people with conditions such as depression, ADHD, bipolar disorder, or a history of brain injury, as well as h…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:17 UTC
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First human tests begin for experimental mental health drug
Knowledge-focused Recruiting nowThis early-stage study aims to understand the safety and side effects of a new medicine called BI 3031185 in adults with borderline personality disorder or ADHD. About 96 participants will take either the medicine or a placebo pill during short stays at a clinic, then switch trea…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: PHASE1 • Sponsor: Boehringer Ingelheim • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:56 UTC
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Can a feeling of shame predict suicide attempts?
Knowledge-focused Recruiting nowThis study aims to understand if a person's tendency to feel shame can help predict future suicide attempts in people with Borderline Personality Disorder (BPD). Researchers will follow 688 adults with BPD for five years, checking in annually with questionnaires and interviews. T…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Mar 09, 2026 14:24 UTC