BORDERLINE PERSONALITY DISORDER
Clinical trials for BORDERLINE PERSONALITY DISORDER explained in plain language.
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New couples therapy offers hope for borderline personality disorder
Disease control Recruiting nowThis study is testing whether a new 12-session therapy for couples, called Sage, works better than standard individual therapy for people with borderline personality disorder (BPD). The therapy involves both the person with BPD and their partner, aiming to improve BPD symptoms, r…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: PHASE2 • Sponsor: York University • Aim: Disease control
Last updated Apr 15, 2026 16:15 UTC
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Could MDMA help people with BPD read emotions better?
Symptom relief Recruiting nowThis study looks at whether a single dose of MDMA can help adults with Borderline Personality Disorder better understand social situations and emotions. Ten participants will take MDMA and then complete tasks and surveys to measure changes in sociability and emotion recognition. …
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: PHASE2 • Sponsor: Yale University • Aim: Symptom relief
Last updated May 17, 2026 01:31 UTC
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New 10-Week therapy shows promise for taming BPD impulsivity in young adults
Symptom relief Recruiting nowThis study tests a 10-week therapy program called SINTYA for young adults aged 16-25 with borderline personality disorder (BPD). The program combines group and individual sessions to help reduce impulsive behaviors and improve emotional control. Researchers will compare impulsivi…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 17, 2026 01:21 UTC
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Video-Based therapy shows promise for teens with borderline symptoms
Symptom relief Recruiting nowThis study tests a group therapy called schema therapy that uses self-recorded videos to help teens with borderline symptoms. About 64 teens will be randomly assigned to either this therapy or standard care. The therapy includes 30 group sessions, 8 individual sessions, and paren…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Turku University Hospital • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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New drug BI 3031185 tested for safety in BPD and ADHD patients
Symptom relief Recruiting nowThis study is testing a new medicine called BI 3031185 in adults with borderline personality disorder (BPD) or attention-deficit/hyperactivity disorder (ADHD). The main goal is to see how safe and tolerable the drug is when given as a single dose. Participants are randomly assign…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: PHASE1 • Sponsor: Boehringer Ingelheim • Aim: Symptom relief
Last updated May 14, 2026 12:02 UTC
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New family-focused approach aims to ease borderline personality disorder struggles
Symptom relief Recruiting nowThis study tests whether adding a case manager and family meetings to standard care helps people with borderline personality disorder function better and feel better. About 100 adults newly accepted into treatment will be randomly assigned to the new program or usual care. The go…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: University Hospital Bispebjerg and Frederiksberg • Aim: Symptom relief
Last updated May 13, 2026 16:01 UTC
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Brain zaps for BPD: new study tests magnetic therapy
Symptom relief Recruiting nowThis study tests whether a non-invasive brain stimulation technique called transcranial magnetic stimulation (TMS) can reduce symptoms of borderline personality disorder (BPD). Up to 30 adults with BPD will receive either real or sham (fake) stimulation over several weeks. The go…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: University of California, Los Angeles • Aim: Symptom relief
Last updated May 12, 2026 13:43 UTC
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Brain training shows promise for borderline personality disorder
Symptom relief Recruiting nowThis study tests a new type of mental training for people with borderline personality disorder (BPD). The training teaches a skill called 'reappraisal-by-distancing,' which helps people step back from negative emotions. Researchers will use brain scans to see if the training chan…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Symptom relief
Last updated May 08, 2026 12:01 UTC
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Eye movement therapy tested for borderline personality disorder
Symptom relief Recruiting nowThis study looks at whether a therapy called EMDR, which is already used for PTSD, can help people with borderline personality disorder (BPD) manage their emotions and behavior better. Researchers will work with 56 adults who have BPD, with or without PTSD, to see if a short cour…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia • Aim: Symptom relief
Last updated May 06, 2026 16:02 UTC
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Brain training shows promise for calming emotional storms in BPD
Symptom relief Recruiting nowThis study tests a new approach for people with borderline personality disorder (BPD) who struggle with intense, unstable emotions. Using real-time brain scans, participants learn to calm an overactive emotion center in the brain. The goal is to see if this training reduces emoti…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: PHASE1, PHASE2 • Sponsor: Central Institute of Mental Health, Mannheim • Aim: Symptom relief
Last updated May 05, 2026 11:56 UTC
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Shame may be a key warning sign for suicide in borderline personality disorder
Knowledge-focused Recruiting nowThis study looks at whether a tendency to feel shame can help predict suicide attempts in people with borderline personality disorder (BPD). Researchers will follow 688 adults with BPD for up to 5 years, tracking their shame levels and any suicide attempts. The goal is to better …
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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Brain zapping study hopes to sharpen minds across 7 disorders
Knowledge-focused Recruiting nowThis study tests whether a mild electrical current applied to the scalp (tDCS) can improve executive functions like memory, attention, and decision-making. Researchers will enroll 600 adults with conditions such as traumatic brain injury, depression, bipolar disorder, schizophren…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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Tailoring emotion skills could transform mental health care
Knowledge-focused Recruiting nowThis study explores whether teaching people emotion regulation skills tailored to their individual needs works better than a one-size-fits-all approach. Researchers will enroll 390 adults with emotional difficulties to test if personalized training reduces daily negative emotions…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Matthew Southward, PhD • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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Zapping the brain to master emotions: new study tests a One-Day training
Knowledge-focused Recruiting nowThis study tests whether a single session of brain stimulation (rTMS) combined with emotion regulation skills training can help people with mood, anxiety, or related disorders better control their emotions. 240 adults aged 18-55 with high emotional distress will be randomly assig…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:50 UTC