Could ecstasy help people with borderline personality disorder connect better?
NCT ID NCT06683014
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This small study at Yale is testing whether a single dose of MDMA (the drug in ecstasy) can improve social cognition—like reading emotions and feeling sociable—in adults with borderline personality disorder. Ten participants will take the drug and complete tasks and surveys. It's an early, open-label trial, so results are preliminary.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MDMA (3,4-methylenedioxymethamphetamine)
What this could lead to
If it works, this could point toward a new way to help people with borderline personality disorder feel more connected and read emotions better.
What could go wrong
This is a very small, early-phase trial with only 10 people and no placebo group. The results may not apply to everyone, and MDMA can have side effects like increased heart rate or anxiety.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Connecticut Mental Health Center
RECRUITINGNew Haven, Connecticut, 06519, United States