BORDERLINE PERSONALITY DISORDER
Clinical trials for BORDERLINE PERSONALITY DISORDER explained in plain language.
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Could a new pill ease borderline personality disorder symptoms?
Symptom relief CompletedThis study tested whether Caplyta (lumateperone), a drug already used for other mental health conditions, can reduce symptoms of borderline personality disorder (BPD). Sixty adults with BPD received either Caplyta or a placebo pill for 8 weeks. Researchers measured changes in BPD…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: PHASE2 • Sponsor: University of Chicago • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC
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New pill aims to calm borderline personality disorder symptoms
Symptom relief CompletedThis study tested an experimental drug called vafidemstat in 211 adults with borderline personality disorder (BPD) to see if it could reduce agitation and aggression. Participants took either the drug or a placebo for 14 weeks. The goal was to measure changes in symptom severity …
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: PHASE2 • Sponsor: Oryzon Genomics S.A. • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Brain zaps without zaps: neurofeedback shows promise for borderline personality disorder
Symptom relief CompletedThis study tested whether real-time brain feedback (rtfMRI) could help people with borderline personality disorder increase brain activity in the amygdala while recalling happy memories. Thirty adults with the condition completed the training over several weeks. The goal was to s…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Kymberly Young • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Can a 6-Month therapy tame Self-Harm? study tests shorter treatment
Symptom relief CompletedThis study compares a 6-month version of dialectical behaviour therapy (DBT) to the standard 1-year program for people with borderline personality disorder who repeatedly self-harm. Researchers want to see if the shorter therapy is just as good at reducing self-harm and is more c…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Centre for Addiction and Mental Health • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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Smartphone app may help tame daily stress in borderline personality
Symptom relief CompletedThis study tested whether a smartphone app called SAM could help adults with borderline personality disorder traits manage daily stress. Sixteen participants used the app for four weeks, answering quick stress questions several times a day and getting feedback on their patterns. …
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: GGZ Centraal • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Watching videos may ease BPD symptoms, study suggests
Symptom relief CompletedThis study tested whether watching short online videos about borderline personality disorder (BPD) could help people recently diagnosed with the condition. 83 adults with BPD watched either BPD-specific videos or general mental health videos over two weeks and completed daily sur…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Mclean Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Magic mushroom compound shows promise for Tough-to-Treat depression and BPD
Symptom relief CompletedThis small Phase 2 trial tested a single 25mg dose of psilocybin in 9 adults with both major depressive disorder and borderline personality disorder. Researchers measured changes in depression and BPD symptoms over time. The goal was to see if psilocybin is safe and could help ea…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: PHASE2 • Sponsor: University of Chicago • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Tiny study asks: does MBT work for Over-60s?
Knowledge-focused CompletedThis small study looked at whether Mentalization-Based Therapy (MBT) helps people aged 60 and older who struggle in relationships. Researchers recruited 3 participants and used interviews and questionnaires to see if the therapy improved their ability to understand their own and …
Matched conditions: BORDERLINE PERSONALITY DISORDER
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC