New pill may tame BPD's worst symptoms

NCT ID NCT04932291

First seen May 08, 2026 · Last updated May 08, 2026

Summary

This study tested an experimental drug called vafidemstat in 211 adults with borderline personality disorder (BPD). The goal was to see if it could reduce agitation and aggression compared to a placebo over 14 weeks. Participants took either the drug or a dummy pill, and doctors tracked symptom changes using standard rating scales.

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Contacts and locations

Locations

  • Adams Clinical Trials, LLC

    Watertown, Massachusetts, 02472, United States

  • Center for Emotioal Fitness

    Cherry Hill, New Jersey, 08002, United States

  • Clinic for psychiatric disorders "Laza Lazarevic"

    Belgrade, 11000, Serbia

  • Clinical center Kragujevac

    Kragujevac, 3400, Serbia

  • Clinical center of Serbia

    Belgrade, 11000, Serbia

  • Core Clinical Research

    Everett, Washington, 98201, United States

  • DCC "Mladost-M" Ltd, Psychiatr

    Varna, 9000, Bulgaria

  • Emovis GmbH

    Berlin, 10629, Germany

  • Excell Research Inc

    Oceanside, California, 92056, United States

  • Excell Research, Inc.

    Oceanside, California, 92056, United States

  • Hospital Clínico San Carlos

    Madrid, 28040, Spain

  • Hospital Vall d'Hebron

    Barcelona, 08035, Spain

  • Klinik fur Psychiatrie und Psychotherapie, LMU

    München, Bavaria, 80336, Germany

  • Medical Center Hera EOOD - Psychiatry Office

    Sofia, Sofia-Grad, 9000, Bulgaria

  • Medical Center Intermedika

    Sofia, Sofia-Grad, 1680, Bulgaria

  • Neurobehavioral Research Inc.

    Cedarhurst, New York, 11516, United States

  • New Life Medical Research Center

    Hialeah, Florida, 33012, United States

  • Phoenix Medical Research LLC

    Miami, Florida, 33165, United States

  • Revive Research Institute

    Elgin, Illinois, 60123, United States

  • The Medical Research Network

    New York, New York, 10128, United States

  • University of Chicago Institutional Review Board

    Chicago, Illinois, 60637-1426, United States

Conditions

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