Can brain training tame emotional storms in BPD?
NCT ID NCT06626789
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether real-time brain training (amygdala neurofeedback) can help people with borderline personality disorder (BPD) feel less intense negative emotions. Participants will either receive real feedback from their own brain activity or a fake (sham) signal while viewing emotional pictures. The goal is to see if learning to calm the amygdala—a brain region linked to emotional reactions—can reduce emotional ups and downs in daily life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
real-time fMRI neurofeedback targeting the amygdala
What this could lead to
If it works, this could offer a new, non-drug way to help people with borderline personality disorder gain better control over overwhelming emotions.
What could go wrong
This is an early-phase trial with only 164 participants, so results may not apply to everyone. The effect might be no better than a placebo (sham) training, and benefits may be small or temporary.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for BORDERLINE PERSONALITY DISORDER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Central Institute of Mental Health
RECRUITINGMannheim, 68159, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
University Clinic Halle (Saale)
NOT_YET_RECRUITINGHalle, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
University Clinic Tuebingen
RECRUITINGTübingen, 72076, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
University Medical Center Hamburg-Eppendorf
RECRUITINGHamburg, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
University clinic Freiburg
RECRUITINGFreiburg im Breisgau, 79104, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
University clinic Giessen
RECRUITINGGiessen, 35392, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••