Can a simple ultrasound predict immunotherapy success?
NCT ID NCT05206942
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study explores whether special ultrasound techniques can detect early signs that cancer immunotherapy is working. Researchers will scan tumors in 30 adults with solid tumors before and after three weeks of treatment. The goal is to see if changes in blood flow measured by ultrasound can predict which patients will respond, potentially offering a faster, safer alternative to waiting for standard scans.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Doppler ultrasound, Long Ensemble Angular-coherence Doppler ultrasound, Contrast-enhanced ultrasound (CEUS) with Lumason contrast agent
What this could lead to
If successful, this could lead to a non-invasive way to quickly tell if immunotherapy is working, helping doctors adjust treatment sooner.
What could go wrong
This is a small, early-stage study (30 participants) that is currently suspended. The ultrasound methods may not reliably predict response, and results may not apply to all tumor types.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Stanford
Palo Alto, California, 94305, United States