Eye transplant showdown: which surgery saves sight best?
NCT ID NCT05289661
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two types of corneal transplant surgery (UT-DSAEK and DMEK) in 160 people with Fuchs dystrophy, a condition that clouds the cornea. It also tests whether a drug called rho-kinase inhibitor can reduce loss of important eye cells after surgery. The goal is to find which approach gives better vision and preserves eye health.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, 03766, United States
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Oregon Health & Science University
Portland, Oregon, 97239, United States
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Stanford University
Palo Alto, California, 94303, United States
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University of California Davis
Sacramento, California, 95817, United States
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University of Miami
Palm Beach Gardens, Florida, 33418, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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Wills Eye Hospital
Philadelphia, Pennsylvania, 19107, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.