Does donor diabetes impact corneal transplant outcomes?

NCT ID NCT05134480

Completed Knowledge-focused Sponsor: Case Western Reserve University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at whether diabetes in a cornea donor affects the success of a corneal transplant called DMEK. Over 1,000 participants received a cornea from either a donor with or without diabetes. Researchers tracked graft failure and cell loss for one year to see if donor diabetes plays a role.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors choose better cornea donors for transplant patients, potentially improving transplant success rates.
What could go wrong: This is an observational study, not a treatment trial. It may not find a clear link between donor diabetes and transplant outcomes, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Fuchs' endothelial dystrophy secondary corneal edema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORNEAL ENDOTHELIAL DECOMPENSATION FUCHS ENDOTHELIAL DYSTROPHY

Contacts and locations

Locations

Price Vision Group

Indianapolis, Indiana, 46260, United States
Verdier Eye Center

Grand Rapids, Michigan, 49546, United States

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