Case Western Reserve University

This study tests whether low-cost fixes for dampness and mold in the home can improve asthma control in children from low-income families. About 80 kids with asthma will be split into two groups: one gets the home repairs right away, the other waits. Researchers will check asthma…

This study compares two surgical techniques to treat gum recession on the lower front teeth. One method uses a flap moved forward plus a graft, while the other uses a different flap design plus a graft. Researchers will measure how much of the exposed tooth root is covered after …

This study compares two ways of attaching a full upper denture to dental implants: attaching it right after implant surgery (immediate loading) versus waiting 3 months (delayed loading). Researchers will track bone loss, gum health, and patient satisfaction over 3 years. The stud…

This study tests whether delivering medically tailored groceries to the homes of pregnant women on Medicaid can reduce food insecurity and improve birth outcomes like preterm birth and low birth weight. About 360 pregnant women in Cuyahoga County, Ohio, will receive home-delivere…

This study tests a program that combines online education, a medication reminder app, and a home blood pressure monitor to help African American adults aged 50+ better manage their hypertension. Participants use these tools for 6 months while continuing their regular care. The go…

This study tests a non-invasive brain stimulation technique (tDCS plus ultrasound) to help people with opioid use disorder and chronic pain reduce drug use. Researchers will compare active stimulation to a sham (fake) treatment in 126 adults already on methadone. The goal is to s…

This early-phase study tests whether adding Arestin (minocycline microspheres) to standard deep cleaning (scaling and root planing) improves gum healing and blood sugar control in adults with type 2 diabetes and moderate to severe gum disease. About 42 participants will be random…

This study follows 480 older adults (average age 74) from low-income housing to see which treatment better stops tooth decay over 3 to 6 years. One group gets a simple painted-on silver solution (SDF) twice a year; the other gets a standard filling plus fluoride varnish. Research…

This study tests a new, single-session therapy called PATH-SS for people struggling with PTSD or depression after a sexual assault. Researchers want to see if this brief treatment reduces distress and is helpful to participants. The study involves 45 adults in Ohio who experience…

This study looks at how the types of bacteria in the mouth change in people with severe gum disease as they go from having some teeth left to having no teeth, and then after getting dental implants. Researchers will collect microbial samples and analyze DNA to see if different im…

This study is testing whether a Peer Support Specialist program can help LGBTQ+ youth (ages 12-17) who are involved in the juvenile justice, child welfare, or mental health systems and have thoughts of suicide or self-harm. The program pairs youth with trained peers to improve re…

This study looks at whether screening college athletes for low energy availability and providing personalized nutrition advice from a sports dietitian can prevent Relative Energy Deficiency in Sport (RED-S). About 300 Division III athletes at Case Western Reserve University will …

This study looks at how small electrical pulses to the brain or arm nerves can help restore sensation in people with spinal cord injuries. Participants already have tiny electrodes implanted as part of a larger study. Researchers will test different stimulation patterns to see wh…

This study looks at whether playing womb-like sounds to preterm infants can help their brains mature and control breathing more steadily. Researchers will monitor 34 babies born at 29-33 weeks for breathing pauses, low oxygen, and slow heart rate. The goal is to understand how ea…

This study looks at whether training medical staff and using electronic health records can encourage older adults (55+) on Medicaid to visit the dentist more often. About 929 participants from 12 primary care clinics will be split into two groups: one where doctors get extra trai…