Case Western Reserve University
Clinical trials sponsored by Case Western Reserve University, explained in plain language.
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Could a diabetes drug shrink dangerous belly fat in HIV patients?
Disease control OngoingThis study tests whether semaglutide, a drug used for diabetes, can reduce harmful belly fat and improve heart health in people with HIV who have excess fat around the midsection (lipohypertrophy). About 108 participants will receive either semaglutide or a placebo for 32 weeks. …
Phase: PHASE2 • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Can cooking classes help kids with type 1 diabetes? new study tests a Kitchen-Based approach
Disease control OngoingThis study tests a 10-lesson family cooking and diabetes education program called DICE for 32 youth aged 8-14 with type 1 diabetes who struggle with blood sugar control. The program aims to improve blood sugar management and reduce health disparities by teaching families practica…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Zapping the brain to quiet diabetic nerve pain
Symptom relief OngoingThis study tests whether two non-invasive brain stimulation techniques—transcranial Direct Current Stimulation (tDCS) and Transcranial Ultrasound (TUS)—can reduce chronic pain in people with diabetic neuropathy. Participants, aged 40 to 80 with foot pain lasting at least 6 months…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Symptom relief
Last updated Jul 01, 2026 00:00 UTC
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New sleep program aims to help exhausted caregivers rest better
Symptom relief OngoingThis pilot study tests a tailored sleep health program for family caregivers who live with and assist a loved one with chronic health conditions. The program combines cognitive behavioral therapy, mindfulness, and caregiving guidance to improve sleep regularity, timing, efficienc…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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New online course could ease the burden on dementia caregivers
Symptom relief OngoingThis study tests a 6-week online program called Learning Skills Together for family caregivers of people with Alzheimer's or related dementias. The program includes weekly group discussions and a workbook covering topics like communication, medication management, and home safety.…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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Can cycling and counseling curb opioid cravings?
Symptom relief OngoingThis study tests whether stationary cycling (at a voluntary or assisted pace) and a type of psychotherapy called I-STOP can reduce drug cravings in adults with opioid use disorder and chronic pain. About 198 people in residential treatment will try these approaches alone or toget…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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App-Based mouth exercises aim to quiet snoring
Symptom relief OngoingThis study tests whether doing simple mouth, tongue, and throat exercises using a mobile app can improve snoring and sleep apnea better than following a paper guide. The 34 participants are adults with mild to severe obstructive sleep apnea who could not or would not use a CPAP m…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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New sleep program aims to help kids with autism sleep better
Symptom relief ENROLLING_BY_INVITATIONThis study tests a behavioral sleep and circadian intervention for 50 school-aged children (6–12 years) with autism who have sleep problems. Parents receive 5 Zoom sessions over 12 weeks to learn strategies to improve their child's sleep. The goal is to see if the program is feas…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Cooking your way to less stress and less food waste?
Knowledge-focused OngoingThis study looks at whether weekly cooking classes can help adults eat better, waste less food, and feel less stressed. About 180 adults will attend in-person classes with cooking and tasting activities. Researchers will measure food waste and other changes over 10 weeks.
Phase: NA • Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Food boxes and cash for Moms-to-Be: can it prevent premature birth?
Knowledge-focused OngoingThis pilot study tests whether providing food boxes and extra money for healthy groceries can reduce food insecurity and improve birth outcomes for pregnant people on Medicaid. About 124 participants will receive either food delivery or financial support, along with recipes and h…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Does donor diabetes impact corneal transplant outcomes?
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at whether corneas from donors with diabetes work as well as those from donors without diabetes after a specific type of corneal transplant called DMEK. Researchers will track 570 participants for 5 years to measure cell loss and overall transplant success. The g…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC