Case Western Reserve University

This study tests if semaglutide, a drug used for diabetes and weight loss, can reduce dangerous belly fat and improve heart health in people with HIV who have extra fat around the waist. About 108 adults with HIV and a high BMI will receive either the drug or a placebo for 32 wee…

This study tests whether a personalized smartphone app (iTAB-CV) plus self-monitoring helps people with bipolar disorder or major depression and high blood pressure take their medication more regularly and lower their blood pressure. About 176 adults aged 21-80 with both conditio…

This study tests a family cooking program called DICE for children aged 8-14 with type 1 diabetes who struggle with blood sugar control. The program teaches families how to cook healthy meals together, aiming to improve blood sugar levels and reduce health gaps. About 32 children…

This pilot study tests whether community health workers can help pregnant people on Medicaid get better access to nutritious food. Researchers will measure food security, depression, social support, and baby outcomes like birthweight and prematurity. The goal is to see if this ap…

This study tests a customized program called Customized Adherence Enhancement (CAE) to help people with bipolar disorder take their medication as prescribed. About 190 participants who struggle with adherence will be randomly assigned to either the CAE program or standard care. T…

This study tests a 6-week online program called Learning Skills Together (LST) for family caregivers of people with Alzheimer's or related dementias. The program teaches practical caregiving skills to help caregivers feel more confident and less depressed. About 216 caregivers wi…

This study tests a behavioral sleep and circadian intervention for 50 school-aged children (6-12 years) with autism spectrum disorder who have sleep problems. The program helps parents improve their child's sleep habits, timing, and quality. The goal is to see if better sleep red…

This study compares using a mobile app versus a printed guide to perform airway exercises for people with mild to severe obstructive sleep apnea who cannot use CPAP. About 34 adults will participate to see if the app improves oxygen levels, snoring, and sleep quality. The goal is…

This study tests whether combining exercise (cycling) with psychotherapy can reduce drug cravings, depression, and anxiety in adults with opioid use disorder and chronic pain. About 198 people in residential treatment will take part. The goal is to find better ways to manage both…

This study looks at whether teaching adults cooking and food skills can lower stress, reduce food waste, and improve their diet. About 180 adults aged 18 and older who can attend in-person classes will take part. Researchers will measure food waste before and after the classes to…

This study looks at whether corneas from donors with diabetes work as well as those from donors without diabetes after a specific type of corneal transplant called DMEK. Researchers will follow 570 people for 5 years to measure cell loss and overall success. The goal is to unders…