Can cycling and counseling curb opioid cravings?
NCT ID NCT05688410
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether stationary cycling (at a voluntary or assisted pace) and a type of psychotherapy called I-STOP can reduce drug cravings in adults with opioid use disorder and chronic pain. About 198 people in residential treatment will try these approaches alone or together. Researchers will also check if these treatments improve depression, anxiety, and sleep.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
exercise (stationary cycling) and psychotherapy (I-STOP)
What this could lead to
If it works, this could point toward a non-drug way to help people in treatment for opioid addiction manage cravings and pain.
What could go wrong
This is an early-stage trial with only 198 participants, so results may not apply to everyone. The effects may be small or not last long-term.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Case Western Reserve University
Cleveland, Ohio, 44106, United States
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University of Colorado at Denver
Denver, Colorado, 80217, United States