Case Western Reserve University
Clinical trials sponsored by Case Western Reserve University, explained in plain language.
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Could a daily dose of grapes help tame Crohn's disease?
Disease control CompletedThis small pilot study tested whether eating grape powder every day could change the mix of gut bacteria in people with Crohn's disease. For 21 days, 21 adults with Crohn's in remission consumed the powder, which is equal to about 1.5 cups of fresh grapes. Researchers measured ch…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Can a bike ride and talk therapy break the cycle of pain and addiction?
Disease control CompletedThis small pilot study tested whether adding exercise and pain-focused talk therapy to standard residential drug treatment is practical and helpful for adults with opioid addiction and chronic pain. Researchers wanted to see if participants could stick with the program and if it …
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Former patients guide others through kidney transplant maze
Disease control CompletedThis study tested whether trained transplant recipients, acting as 'navigators,' could help other kidney failure patients complete the many steps needed to get a transplant. It involved about 170 adult patients on dialysis, comparing those who received help from a navigator with …
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Sleep program aims to tame blood sugar in young diabetics
Disease control CompletedThis study tested whether a program to help young adults with type 1 diabetes get more and more consistent sleep could improve their blood sugar control. Researchers compared a sleep coaching program to standard diabetes education in 39 participants. The goal was to see if better…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Community & nurse team up to fight stroke in black men
Disease control CompletedThis study tested a 6-month support program designed to help African American men who have already had a stroke or mini-stroke (TIA). The program paired participants with a nurse and a peer educator who had also experienced a stroke. Researchers compared this team approach to a w…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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Study tests cutting Seizure-Prevention drug time in half for new moms
Disease control CompletedThis study looked at whether a shorter course of magnesium sulfate is just as safe and effective as the standard longer course for preventing seizures after delivery in women with mild preeclampsia. Researchers compared giving the medication for 12 hours versus 24 hours after bir…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated Mar 02, 2026 15:23 UTC
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Can text messages help more black moms breastfeed?
Prevention CompletedThis study tested whether a special text message program designed for Black expectant mothers could help more women breastfeed exclusively for the first two months. Researchers compared this tailored program to a general national maternal health texting service. The goal was to p…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Prevention
Last updated Mar 16, 2026 15:24 UTC
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New dads get health boost at birth center
Prevention CompletedThis study tested different ways to encourage men to get preventive healthcare, like vaccines, when they visit a partner at a birthing center. Researchers compared simply offering vaccines at the bedside to also providing health information or connecting men to a men's health cen…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Prevention
Last updated Mar 06, 2026 15:37 UTC
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Needles in the ER: study tests ancient practice for modern pain
Symptom relief CompletedThis study tested whether offering acupuncture is a practical way to help manage pain for adults visiting the emergency department. Researchers compared acupuncture to standard pain care across three hospitals to see if it was feasible to run a larger future trial. They measured …
Phase: NA • Sponsor: Case Western Reserve University • Aim: Symptom relief
Last updated Mar 13, 2026 15:05 UTC
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Scientists hunt for high blood pressure genes in thousands
Knowledge-focused CompletedThis study aimed to understand the genetic causes of high blood pressure. Researchers analyzed previously collected DNA samples from 8,687 participants, focusing on African American, Mexican American, Nigerian, and Jamaican groups. The goal was to identify specific gene variation…
Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Can a diabetic Donor's cornea save your sight?
Knowledge-focused CompletedThis study aimed to find out if corneas from donors with diabetes work as well for transplants as those from donors without diabetes. Over 1,000 patients needing a specific type of corneal transplant (DMEK) received tissue from either a diabetic or non-diabetic donor. Researchers…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Can learning to cook with what you have reduce stress and waste?
Knowledge-focused CompletedThis study explored a new way to teach cooking and food skills to adults. Researchers tested classes that focused on improvisational cooking (using ingredients on hand), reducing food waste, and proper food storage. The goal was to see if this approach was practical and acceptabl…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC
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Sensors could forecast stroke recovery
Knowledge-focused CompletedThis study tested whether a special sensor system could predict how well stroke patients recover arm movement. Researchers measured 30 stroke patients' arm movements with sensors during their first month after stroke. They compared these measurements to standard recovery tests to…
Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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3D-Printed hearts vs. slides: which teaches Doctors-in-Training better?
Knowledge-focused CompletedThis study tested whether 3D-printed heart models or augmented reality (AR) could help first-year medical students learn about complex heart defects better than traditional slide-based lectures. Twenty-six students were split into three groups to learn using slides, 3D models, or…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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Smart ring study sheds light on sleep and snoring in orthodontic patients
Knowledge-focused CompletedThis study aimed to understand sleep quality and breathing patterns in adults undergoing orthodontic treatment. Researchers enrolled 52 patients and had them wear a smart ring and use a phone app for a week to track sleep, snoring, and oxygen levels. The goal was to gather data t…
Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:03 UTC