Case Western Reserve University
Clinical trials sponsored by Case Western Reserve University, explained in plain language.
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New program aims to boost medication adherence in bipolar youth
Disease control CompletedThis study tested a behavioral program called CAE-AYA to help teens and young adults with bipolar disorder take their medication more consistently. The program included up to five in-person sessions and a follow-up phone call over eight weeks. Researchers measured adherence using…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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Phone app helps patients with mood disorders stick to blood pressure meds
Disease control CompletedThis study tests whether a personalized mobile health app (iTAB-CV) plus self-monitoring helps people with bipolar disorder or major depression take their blood pressure medication more regularly and lower their blood pressure. About 176 adults aged 21-80 with both conditions and…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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New behavioral program aims to solve medication adherence in bipolar disorder
Disease control CompletedAbout half of people with bipolar disorder struggle to take their medication as prescribed, which can lead to severe consequences. This study tested a customized program called Customized Adherence Enhancement (CAE) that includes education, motivational interviewing, and help wit…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New group program aims to cut stroke risk in African-American men
Disease control CompletedThis study tested a 6-month program called TEAM designed to help African-American men who have had a stroke or mini-stroke manage their health better. The program included group sessions with a nurse and peer educators, focusing on lifestyle changes to lower blood pressure and ch…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Grape powder shows promise for Crohn's gut health
Disease control CompletedThis study tested whether a daily dose of grape powder (46 grams) could improve gut bacteria and reduce inflammation in adults with Crohn's disease who were in remission. Twenty-one participants took the grape powder and provided stool and blood samples. The goal was to see if gr…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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Sleep coaching shows promise for blood sugar control in young diabetics
Disease control CompletedThis study tested whether a sleep coaching program could help young adults (ages 18-26) with type 1 diabetes sleep longer and improve their blood sugar levels. Participants received personalized sleep advice and weekly check-ins over several weeks. The goal was to see if better s…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Could half the magnesium dose after delivery be just as safe?
Disease control CompletedThis study looked at whether giving magnesium sulfate for 12 hours after delivery instead of the usual 24 hours is safe and effective for preventing seizures in women with mild preeclampsia. Researchers enrolled 200 women and compared the two treatment lengths. The goal was to se…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated Jun 26, 2026 16:35 UTC
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Dads get shots too: new strategy boosts Men's preventive care
Prevention CompletedThis study tested whether offering vaccines and health education to men at a birthing center helps them get more preventive care. 176 male partners of birthing people were split into three groups: one got a vaccine offer, another got an info flyer plus the offer, and a third got …
Phase: NA • Sponsor: Case Western Reserve University • Aim: Prevention
Last updated Jun 27, 2026 13:03 UTC
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New painkiller may ease wisdom tooth recovery better than standard option
Symptom relief CompletedThis study tested whether a long-acting painkiller called Exparel works better than standard bupivacaine for pain after removing all four wisdom teeth. 82 adults took part and reported their pain and side effects for four days after surgery. The goal was to see which drug provide…
Phase: PHASE4 • Sponsor: Case Western Reserve University • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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Exercise and talk therapy show promise for opioid pain relief
Symptom relief CompletedThis pilot study tested whether adding exercise and pain-focused therapy to residential drug treatment is practical and helpful. 63 adults with opioid use disorder and pain took part. The goal was to see if they would stick with the program and if it could reduce pain, cravings, …
Phase: NA • Sponsor: Case Western Reserve University • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Needles over pills? ER study tests acupuncture for acute pain
Symptom relief CompletedThis study looked at whether acupuncture can help manage pain for people visiting the emergency department with common painful conditions like back pain or abdominal pain. About 290 adults were split into two groups: one received acupuncture, the other got usual care. The goal wa…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Can a soy diet soothe Crohn's? new study investigates gut bacteria changes
Knowledge-focused CompletedThis study looked at how a soy-based diet or a similar diet without soy changes gut bacteria in people with Crohn's disease (in remission or active) and healthy volunteers. Researchers measured inflammation markers and tracked whether symptoms stayed stable over one week. The goa…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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New study explores why some african americans thrive despite high blood pressure
Knowledge-focused CompletedThis study looked at 125 African American adults with high blood pressure to understand what helps them stick to their treatment and stay resilient. Researchers measured blood pressure, quality of life, and self-management behaviors over 6 months. The goal is to find new ways to …
Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Does donor diabetes impact corneal transplant outcomes?
Knowledge-focused CompletedThis completed study looked at whether diabetes in a cornea donor affects the success of a corneal transplant called DMEK. Over 1,000 participants received a cornea from either a donor with or without diabetes. Researchers tracked graft failure and cell loss for one year to see i…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Cooking classes may cut stress and food waste, tiny study hints
Knowledge-focused CompletedThis pilot study tested a weekly cooking and food skills program called Nourish in 26 healthy adults. Participants attended in-person classes with hands-on cooking, received groceries and kitchen tools, and tracked their food waste. The goal was to see if the classes could improv…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Can a ring and app track your sleep? new study finds out
Knowledge-focused CompletedThis study looked at how well smartphone apps and a special ring (Belun Ring) can measure sleep quality in adults getting braces or other orthodontic treatment. 52 people from Case Western Reserve University's dental clinic took part. They answered sleep questionnaires and used t…
Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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3D hearts and AR boost med student learning in heart defect study
Knowledge-focused CompletedThis study tested whether 3D-printed heart models or augmented reality (AR) help first-year medical students understand two rare heart defects better than traditional slide lectures. 26 students took a quiz before and after learning with one of the three methods. The goal was to …
Phase: NA • Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Wearable sensors could predict stroke arm recovery
Knowledge-focused CompletedThis study tested a wearable sensor system (IMAS) to measure arm movement in 30 people who recently had a stroke. The goal was to see if the sensors could accurately predict how well arm function would recover. Researchers used motion data to build a model and compared it to stan…
Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Texts boost breastfeeding in black moms, study finds
Knowledge-focused CompletedThis study tested a text-message program designed to support African-American/Black mothers in breastfeeding. About 80 pregnant women who planned to breastfeed received either the special program or a general health text service. Researchers measured how many women were still bre…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Navigators may bridge kidney transplant gap for minorities and women
Knowledge-focused CompletedThis study tested whether trained transplant navigators could help kidney failure patients complete the steps needed to get a kidney transplant. About 167 adults on dialysis were assigned to either a navigator or usual care. The navigator provided tailored help and information to…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Gene hunt for high blood pressure in thousands completed
Knowledge-focused CompletedThis study looked for genetic differences that might make some people more likely to develop high blood pressure. Researchers analyzed data from nearly 9,000 African American and Mexican American participants. The goal was to find specific gene variations linked to hypertension, …
Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:13 UTC