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New program aims to boost medication adherence in bipolar youth

NCT ID NCT04348604

Completed Disease control Sponsor: Case Western Reserve University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a behavioral program called CAE-AYA to help teens and young adults with bipolar disorder take their medication more consistently. The program included up to five in-person sessions and a follow-up phone call over eight weeks. Researchers measured adherence using questionnaires and a special pill bottle that records when it's opened. The goal was to see if this approach could improve medication routines and reduce the risk of relapse and suicide in this high-risk group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Customized Adherence Enhancement for Adolescents and Young Adults (CAE-AYA) - a behavioral program
What this could lead to
If successful, this program could help young people with bipolar disorder stick to their medication routine, potentially reducing relapses and suicide risk.
What could go wrong
This is a small, completed study with only 36 participants, so results may not apply to everyone. The program requires in-person sessions, which may not be practical for all.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bipolar disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BIPOLAR DISORDER

Contacts and locations

Locations

  • Case Western Reserve Universty

    Cleveland, Ohio, 44106, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45219, United States

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