New behavioral program aims to solve medication adherence in bipolar disorder
NCT ID NCT04622150
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
About half of people with bipolar disorder struggle to take their medication as prescribed, which can lead to severe consequences. This study tested a customized program called Customized Adherence Enhancement (CAE) that includes education, motivational interviewing, and help with medication routines. Researchers enrolled 190 adults with bipolar disorder in public mental health clinics to see if CAE improves adherence compared to usual care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Customized Adherence Enhancement (CAE) - a behavioral program with modules like education, motivational interviewing, and medication routines
What this could lead to
If it works, this could provide a practical, evidence-based tool for mental health clinics to help people with bipolar disorder take their medication more consistently.
What could go wrong
This is a completed trial with 190 participants, but it tests a behavioral intervention, not a drug, so results may be modest and depend on how well clinics adopt the program.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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MetroHealth Medical Center
Cleveland, Ohio, 44109, United States
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The Nord Center
Lorain, Ohio, 44053, United States
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W.O. Walker Center
Cleveland, Ohio, 44106, United States