HIV belly fat breakthrough? semaglutide trial targets hidden dangers

NCT ID NCT04019197

First seen Feb 20, 2026 · Last updated May 16, 2026 · Updated 8 times

Summary

This study tests if semaglutide, a drug used for diabetes and weight loss, can reduce dangerous belly fat and improve heart health in people with HIV who have extra fat around the waist. About 108 adults with HIV and a high BMI will receive either the drug or a placebo for 32 weeks. The goal is to see if the drug lowers fat inside the belly and around organs, which may lower the risk of heart disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Case Western Reserve University

    Cleveland, Ohio, 44106, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

Conditions

Explore the condition pages connected to this study.