Zapping the brain to quiet diabetic nerve pain
NCT ID NCT03625752
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This study tests whether two non-invasive brain stimulation techniques—transcranial Direct Current Stimulation (tDCS) and Transcranial Ultrasound (TUS)—can reduce chronic pain in people with diabetic neuropathy. Participants, aged 40 to 80 with foot pain lasting at least 6 months, will receive either active or sham stimulation over several sessions. The goal is to see if these methods can safely lower pain intensity and improve function without drugs.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
transcranial Direct Current Stimulation (tDCS) and Transcranial Ultrasound (TUS)
What this could lead to
If it works, this could offer a drug-free way to ease chronic pain from diabetic neuropathy, improving daily life for many.
What could go wrong
This is a small, early-stage study with 60 participants, so results may not apply to everyone. The effects may be modest or temporary.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ciro Ramos Estebanez
Chicago, Illinois, 60612, United States
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University Hospitals Cleveland Medical Center/ Dahms Clinical Research Unit
Cleveland, Ohio, 44106-1716, United States