Could a 15-minute dip in your own blood save your cornea transplant?

NCT ID NCT06261346

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether briefly soaking a donor cornea in a solution made from the patient's own blood (PRGF) before transplant surgery can reduce the loss of important cells after the operation. About 100 people with Fuchs' endothelial dystrophy or corneal swelling will take part. The goal is to see if this simple, one-time step helps the graft stay healthy longer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Plasma Rich in Growth Factors (PRGF)

What this could lead to

If it works, this could improve graft survival and reduce the need for repeat corneal transplants.

What could go wrong

This is a small, early-phase study with no control group, so results may not be conclusive. The procedure adds only 15 minutes, but benefits are uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

corneal edema Fuchs' endothelial dystrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bascom Palmer Eye Institute

    RECRUITING

    Miami, Florida, 33136, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Price Vision Group

    RECRUITING

    Indianapolis, Indiana, 46260, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact