Could a 15-minute dip in your own blood save your cornea transplant?

NCT ID NCT06261346

Recruiting now Disease control Sponsor: University of Miami Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether briefly soaking a donor cornea in a solution made from the patient's own blood (PRGF) before transplant surgery can reduce the loss of important cells after the operation. About 100 people with Fuchs' endothelial dystrophy or corneal swelling will take part. The goal is to see if this simple, one-time step helps the graft stay healthy longer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Plasma Rich in Growth Factors (PRGF)
What this could lead to: If it works, this could improve graft survival and reduce the need for repeat corneal transplants.
What could go wrong: This is a small, early-phase study with no control group, so results may not be conclusive. The procedure adds only 15 minutes, but benefits are uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

corneal edema Fuchs' endothelial dystrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORNEAL EDEMA FUCHS ENDOTHELIAL DYSTROPHY

Contacts and locations

Locations

Bascom Palmer Eye Institute
RECRUITING

Miami, Florida, 33136, United States
Price Vision Group
RECRUITING

Indianapolis, Indiana, 46260, United States

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