New eye injection could restore sight in corneal swelling patients

NCT ID NCT07368959

Recruiting now Disease control Sponsor: Aurion Biotech Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a single injection of AURN001 in 120 adults with corneal swelling caused by endothelial dysfunction. The goal is to see if it improves vision and reduces corneal thickness compared to a placebo. Participants must already have an artificial lens in the eye and be candidates for corneal transplant surgery.

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Conditions

The condition(s) this trial relates to.

bullous keratopathy corneal edema Fuchs' endothelial dystrophy secondary corneal edema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORNEAL EDEMA CORNEAL ENDOTHELIAL DYSFUNCTION FUCHS ENDOTHELIAL CORNEAL DYSFUNCTION PSEUDOPHAKIC BULLOUS KERATOPATHY (PBK)

Contacts and locations

Locations

Investigational Site 1
RECRUITING

Spring, Texas, 77388, United States
Investigational Site 10
RECRUITING

Plymouth Meeting, Pennsylvania, 19462, United States
Investigational Site 11
RECRUITING

Leland, North Carolina, 28451, United States
Investigational Site 12
RECRUITING

Ladson, South Carolina, 29456, United States
Investigational Site 2
RECRUITING

Mesa, Arizona, 85206, United States
Investigational Site 3
RECRUITING

Cynwyd, Pennsylvania, 19004, United States
Investigational Site 4
RECRUITING

Kansas City, Missouri, 64154, United States
Investigational Site 5
RECRUITING

Winston-Salem, North Carolina, 27157, United States
Investigational Site 6
RECRUITING

Little Rock, Arkansas, 72205, United States
Investigational Site 7
RECRUITING

Atlanta, Georgia, 30339, United States
Investigational Site 8
RECRUITING

San Antonio, Texas, 78209, United States
Investigational Site 9
RECRUITING

Fort Collins, Colorado, 80528, United States

More trials for these conditions

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