Eye injection could replace cornea transplants for swollen corneas

NCT ID NCT07368959

First seen Jan 31, 2026 · Last updated May 01, 2026 · Updated 14 times

Summary

This study tests a single injection of AURN001 in 120 adults with corneal swelling caused by endothelial dysfunction, a condition that often requires a cornea transplant. The goal is to see if the injection improves vision by at least 3 lines on an eye chart and reduces corneal thickness at 6 months, compared to a placebo. Participants must already have an artificial lens in the eye and have vision between 20/50 and 20/800.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Investigational Site 1

    RECRUITING

    Spring, Texas, 77388, United States

  • Investigational Site 10

    RECRUITING

    Plymouth Meeting, Pennsylvania, 19462, United States

  • Investigational Site 11

    RECRUITING

    Leland, North Carolina, 28451, United States

  • Investigational Site 12

    RECRUITING

    Ladson, South Carolina, 29456, United States

  • Investigational Site 2

    RECRUITING

    Mesa, Arizona, 85206, United States

  • Investigational Site 3

    RECRUITING

    Cynwyd, Pennsylvania, 19004, United States

  • Investigational Site 4

    RECRUITING

    Kansas City, Missouri, 64154, United States

  • Investigational Site 5

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

  • Investigational Site 6

    RECRUITING

    Little Rock, Arkansas, 72205, United States

  • Investigational Site 7

    RECRUITING

    Atlanta, Georgia, 30339, United States

  • Investigational Site 8

    RECRUITING

    San Antonio, Texas, 78209, United States

  • Investigational Site 9

    RECRUITING

    Fort Collins, Colorado, 80528, United States

Conditions

Explore the condition pages connected to this study.