Saline showdown: which eye drop clears Post-Surgery swelling faster?
NCT ID NCT07605273
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study tested whether a stronger (5%) or weaker (3%) saltwater eye drop works better to reduce corneal swelling after cataract surgery. 70 adults who developed swelling after surgery received one of the two treatments. The main goal was to see which drop thinned the cornea more effectively.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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70 people
The number who actually took part.
- Started
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Jun 2025
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients of any gender * Aged 18 years and above * Patients who went through phacoemulsification with cumulative dissipated energy (CDE) between 25 and 40 units and developed corneal edema as a postoperative complication. Exclusion Criteria: * Patients predisposed to corneal edema due to corneal dystrophies, including Fuch's endothelial dystrophy, posterior polymorphous corneal dystrophy, or congenital hereditary endothelial dystrophy. * With pre-existing inflammatory conditions like primary endothelitis or stromal viral keratitis * Any prior trauma to the eye affecting study outcomes. * Allergic to normal saline. * On oral or topical steroids for the last month.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Pakistan Air Force (PAF) hospital/Fazaia Post Graduate Medical Institute
Islamabad, Punjab Province, 44000, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Could a 15-minute dip in your own blood save your cornea transplant?
- New eye injection could restore sight in corneal swelling patients
- New artificial cornea implant offers hope for patients with failed transplants
- First human trial of Lab-Grown corneal implant launches
- Eye injection could replace corneal transplants for swelling