Stanford University

This study tested a type of family therapy (FBT-ARFID) against usual care for 98 children aged 6 to 12 with Avoidant/Restrictive Food Intake Disorder (ARFID). The therapy involves 14 weekly sessions over 4 months, focusing on empowering parents to change their child's eating beha…

This study tested two behavioral weight-loss programs in 321 adults with obesity and elevated blood pressure. One group learned key maintenance skills before losing weight, while the other focused on losing weight first. Researchers tracked weight changes over 3 years to see whic…

This study tested two types of endoscopes used in a procedure called ERCP, which helps diagnose and treat bile duct and pancreas problems. One scope had a disposable cover on its tip, while the other was a standard reusable scope. Researchers compared how well each worked and how…

High blood pressure affects nearly half of Americans, but only half have it under control. This study tested whether a digital program—including personalized health coaching and a connected blood pressure cuff used via smartphone or website—could improve blood pressure control co…

This early-phase study tested a combination of two drugs, bexarotene and Iressa, in 6 people with advanced non-small cell lung cancer who had already tried standard treatments. The goal was to see if the combination was safe and could help control the disease. The study looked at…

This study tested the drug alirocumab in 114 heart transplant recipients to see if it safely reduces plaque buildup in the new heart's arteries. The drug targets a protein called PCSK9 to lower harmful cholesterol. Researchers measured changes in artery plaque using ultrasound at…

This study tested a very strong dose of chemotherapy followed by a stem cell rescue in 203 people with breast cancer that responded to standard chemo. The goal was to see if this approach could help them live longer. The treatment is intense and not a cure, but aims to control th…

This study tested whether adding the drugs omalizumab (Xolair) or dupilumab (Dupixent) to oral immunotherapy (OIT) helps people with multiple food allergies tolerate more allergens. 130 participants aged 4 to 55 with allergies to peanut plus one or two other foods were enrolled. …

This study tested a daily pill called acebilustat in 40 adults with arm lymphedema (swelling from poor lymph drainage). Participants took either the drug or a placebo for 9 months. Researchers measured changes in skin thickness and arm structure to see if the drug helps reduce sw…

This study tested whether adding a support person—like a family member or friend—to standard buprenorphine treatment helps people with opioid addiction stay in treatment longer. 439 patients and their support persons took part. The support persons learned CRAFT, a counseling prog…

This early-phase study tested a combination of tumor treating fields (a device that creates electric fields to disrupt cancer growth), stereotactic radiosurgery (precise radiation), and temozolomide chemotherapy in 12 adults with newly diagnosed glioblastoma. The main goal was to…

This study tested whether adding high-dose radiation to standard immunotherapy can better control advanced non-small cell lung cancer that has spread. 45 adults with stage IV cancer who were already on immunotherapy received targeted radiation to their tumors. The goal was to see…

This study tested a treatment called hemofiltration (a type of dialysis) in 6 children who had breathing failure after a bone marrow transplant. The idea was to filter out harmful inflammatory molecules from the blood to reduce lung damage and improve survival. The main goal was …

This study tested the drug trametinib in 25 people aged 12 to 60 with complicated arteriovenous malformations (AVMs), which are abnormal blood vessel tangles that can cause pain, bleeding, and heart problems. The goal was to see if the drug could shrink the malformations and impr…

This study looked at 1,500 people with severe blockages in three heart arteries. It compared a less invasive procedure using a pressure wire to guide stent placement (FFR-guided PCI) with open-heart bypass surgery (CABG). The goal was to see if the stent approach could match the …

This study tested a program called 4T (Teamwork, Targets, Technology, and Tight Control) in 316 children and teens newly diagnosed with type 1 diabetes. The program aimed to help them manage blood sugar levels and improve their quality of life using continuous glucose monitors an…

This study looked at whether eating a whole-food, plant-based diet for 8 weeks could lower markers of cancer and inflammation in firefighters. 121 active firefighters participated. Researchers measured changes in blood markers like IL-6 and C-reactive protein to see if the diet m…

This study tested whether giving people a low-sodium salt substitute (where part of the sodium is replaced with potassium) can help lower blood pressure. Over 600 adults in rural Bangladesh received the salt substitute from community health workers. The goal was to see if this si…

This early-phase study tested an oral drug called idebenone in 53 adults with non-alcoholic steatohepatitis (NASH) and mild-to-moderate liver scarring. The main goal was to check safety and tolerability, while also looking for signs that the drug might reduce liver stiffness and …

This early-phase study tested whether specially grown immune cells (cytokine-induced killer cells) could safely treat blood cancers that return after a stem cell transplant. 21 adults with relapsed multiple myeloma or other blood cancers received these donor cells. The goal was t…

This early-phase study tested a three-drug combination (carfilzomib, cyclophosphamide, and etoposide) in 4 children whose solid tumors or leukemias had come back or didn't respond to standard treatment. The main goal was to find the safest dose and identify side effects. The stud…

This study looked at blood samples from 573 people to find new markers that could diagnose liver cancer more accurately. Researchers compared samples from patients with liver cancer, those with other liver conditions, and people with hepatitis infections. The goal is to improve u…

This study tested whether a Samsung Galaxy Watch can reliably detect moderate to severe obstructive sleep apnea (OSA) in adults. Researchers enrolled 152 people who were at high risk or already diagnosed with OSA. The watch's readings were compared to standard sleep tests to see …

This study tested a school-based curriculum called Be Vape Free, designed to prevent e-cigarette use among middle and high school students. Nearly 2,800 students participated in the program, which was delivered in classrooms. Researchers measured changes in e-cigarette use, inten…

This study tested whether adjusting the dose of a tuberculosis (TB) prevention drug based on a person's genetic makeup could improve treatment. Researchers enrolled 78 people and used a quick genetic test to guide the dose of isoniazid. The goal was to see if this personalized ap…

This study tested a single online session called webCHAT to see if it could reduce impaired driving among teens. 198 adolescents aged 15.5 to 17 who were enrolled in driver education took part. The program aimed to help them make safer choices about alcohol, cannabis, and driving…

This study tested whether using box fans with special filters and improving home ventilation could lower the chance of COVID-19 spreading from one infected person to others living in the same home. Researchers studied 214 people living in households with at least 3 members. The g…

This study tested whether a mobile health app could help women who had a preterm baby reduce the risk of another preterm birth. The app focused on improving patient engagement, care coordination, and following medical advice, especially around pregnancy spacing. 221 women with a …

This study tested whether using a virtual reality headset showing calming scenery for 20-30 minutes could lower anxiety in parents whose children were in the hospital. 485 parents participated, and their anxiety levels were measured and compared to standard care without any tech-…

This study tested whether a sleep therapy called CBT-I could reduce depression and anxiety by improving how the brain controls emotions. 51 adults with poor sleep and depression symptoms took part. They met with a psychologist weekly for six weeks to learn better sleep habits. Th…

This study tested whether a special knee brace, called a Tri-Compartment Unloader, can reduce pain and improve function in people with anterior knee pain. Twenty adults with knee pain that worsens when bending and bearing weight wore the brace during physical therapy and daily ac…

This study tested whether adding a palliative care team to standard surgical care improves quality of life for patients with gastrointestinal cancers and their families. 379 patients and their companions were randomly assigned to receive either surgeon care alone or surgeon care …

This study tested whether a weak electrical current applied to the head (called TES) can help control pain after major sleep apnea surgery. 45 adults received either a combined direct and alternating current or direct current only through skin electrodes. The goal was to see if t…

This study tested whether a nerve block (suprazygomatic maxillary nerve block) can reduce pain and the need for strong painkillers in children after tonsil and adenoid removal. 114 children aged 6 months to 18 years took part. The block was given during surgery, and some children…

This study tested whether injecting a person's own processed fat tissue into the knee can reduce pain and improve function in people with knee osteoarthritis. Forty adults with moderate knee arthritis received either the fat injection or a standard steroid shot. The goal was to s…

This study tested a therapy called pivotal response treatment (PRT) for 75 preschoolers with autism. The therapy focuses on improving social communication skills through play in a center-based setting. Researchers measured changes in social responsiveness and communication over 1…

This study tested whether the drug Lemborexant helps people with delayed sleep phase syndrome (a condition where your natural sleep time is much later than desired) fall asleep faster. 71 adults took either the drug or a placebo nightly for up to 2 years. The main goal was to see…

This pilot study tested whether a virtual therapy platform called Teleo helps children with anxiety or mood disorders stay more engaged in psychotherapy compared to standard video conferencing. 41 children participated, and researchers measured engagement using video coding and c…

This study tested an accelerated schedule of theta-burst stimulation, a type of brain stimulation, in 40 people with treatment-resistant depression. Participants received multiple sessions per day targeting the left or both sides of the brain. Researchers measured changes in depr…

This study tested whether a live-video-supervised exercise program could improve fitness in children and teens (ages 8-19) born with a single ventricle, a condition often treated with the Fontan procedure. Participants exercised three times a week for three months, then a mainten…

This completed phase 2 trial tested whether taking Paxlovid for 15 days reduces severe Long COVID symptoms compared to a placebo. 168 adults with persistent symptoms like fatigue, brain fog, and shortness of breath participated. Researchers tracked symptom severity over 15 weeks …

This study tested whether using a virtual reality (VR) headset to do fun activities could help ease depression symptoms. 26 adults with major depressive disorder were asked to complete four activities each week—either in VR (like games or social interactions) or in real life. Res…

This study tested a digital tool called Noona that lets advanced cancer patients track their symptoms on their own devices. The goal was to see if it improves patient engagement and quality of life compared to usual care. 190 patients with advanced lung or gastrointestinal cancer…

This study tested whether a nasal spray containing vasopressin, a natural hormone, can improve social functioning in children with autism. 157 children aged 6 to 17 took part. Researchers measured changes in social responsiveness and overall symptoms over 8 weeks.

This study looked at 113 adults with carpal tunnel syndrome to see if there is a difference in pain and hand function shortly after surgery. One group had endoscopic surgery (small incisions) and the other had open surgery (larger incision). Researchers measured pain and function…

This study tested a computer-based training program designed to change how people with Obsessive-Compulsive Disorder (OCD) process emotions. Five adults with OCD completed the training to see if it could reduce their repetitive thoughts and behaviors. The goal was to find a new, …

This study tested whether parents can learn a proven autism therapy called Pivotal Response Treatment (PRT) through secure video calls. 101 children aged 2-5 with autism and language delays took part. Parents received weekly 60-minute training for 12 weeks. The goal was to see if…

This study tested a new, faster type of brain stimulation (called aiTBS) in 79 adults with treatment-resistant depression. The goal was to see if it could improve symptoms like loss of pleasure and interest. Researchers used brain scans to personalize the stimulation for each per…

This study looked at whether adding buprenorphine to ketamine treatment can reduce suicidal thoughts faster and longer in adults with major depression. About 50 people took part. Researchers measured changes in suicidal thinking over several weeks to see if the combination worked…

This study tested two cooling methods to help outdoor workers lower their body temperature and avoid heat illness. 40 workers were monitored while using cooling vests or other cooling techniques. The goal was to see which method works best to keep core temperature down during hot…

This study tested whether a single dose of cabergoline can prevent breast pain, engorgement, and milk leakage in people who had an abortion or pregnancy loss between 16 and 20 weeks. 69 participants were randomly assigned to receive cabergoline or a placebo. The goal was to see i…

This small pilot study tested an accelerated version of theta-burst stimulation, a type of magnetic brain stimulation, in 7 adults with bipolar depression that didn't respond to standard treatments. All participants received the active treatment, and researchers measured changes …

This study compared two antidepressant medications, duloxetine and desipramine, to see which one reduces pain better in people with chronic pain. About 86 adults with pain lasting more than 3 months took one of the two drugs for six months. The main goal was to see how many peopl…

This study tested whether using virtual reality (VR) during physical therapy helps children and young adults (ages 7-25) move more and enjoy therapy more. Sixty participants did both VR-assisted and traditional therapy sessions. Researchers measured activity levels with a watch-l…

This study tested whether adding virtual reality (VR) to standard physical therapy helps teenagers with long-term muscle or bone pain. 34 teens aged 10-17 used VR while doing exercises to see if it was easy, fun, and helpful. The goal was to reduce fear of movement and improve ph…

This study tested a new type of deep brain stimulation (DBS) that adjusts its settings in real time to help people with Parkinson's disease who experience freezing of gait—a sudden inability to move their feet. Unlike standard DBS, which delivers constant stimulation, this adapti…

This study tested whether a device that uses sound and audio feedback (called NOICE) can help people feel less pain from cold. 42 healthy adults took part, and each tried both the device and no device at different times. The goal was to see if the device could lower pain scores a…

This study tested a one-time pain management class for young people aged 10 to 18 with chronic pain. The class taught about pain science and simple skills to help manage pain. Researchers checked if the class was easy to use and liked by participants, and if it helped reduce pain…

This study looked at a voluntary program to help people with chronic pain slowly lower their opioid medications. 51 adults who wanted to reduce their opioid dose worked with their doctor over 4 months using a personalized tapering plan and a self-help book. The main goal was to s…

This study tested whether a short program that encourages doctors to see daily food choices as acts of self-kindness can improve their self-compassion and reduce burnout. 177 US physicians took part over 6 weeks. The goal was to find a practical way to help doctors care for thems…

This study tested a procedure called cryoneurolysis, which uses a special device to freeze the nerves around broken ribs. The goal was to see if it could provide better pain relief and reduce the need for strong painkillers like opioids. The study included 43 adults aged 18 to 64…

This study tested a digital program called 'Empowered Relief: On-Demand' to help people with chronic pain who misuse prescription opioids. 234 adults were randomly assigned to either the pain skills app or a health education app. Researchers measured pain levels, opioid cravings,…

This study tested whether pregnenolone, a natural hormone in the brain, can help reduce irritability and improve social communication in people with autism. Forty participants aged 14 to 25 took the hormone or a placebo for several weeks. Researchers measured changes in behavior …

This study tested whether virtual reality (VR) experiences are practical and helpful for older adults with serious illnesses living in nursing homes. 52 participants tried computer-generated or film-based VR. Researchers measured symptoms like pain and anxiety, and how relaxed th…

This study tested whether watching short, animated storytelling videos could make people more aware of their smartphone overuse and help them cut back. Researchers enrolled 6,000 adults in the US who own a smartphone. Participants watched the videos and reported their phone addic…

This study tested whether adding in-home decluttering practice to a group workshop (Buried in Treasures) helps people with hoarding disorder. 41 adults aged 18-70 took part. The goal was to reduce clutter, difficulty discarding, and excessive acquiring. Results were measured usin…

This study tested a portable device that creates a temporary, nanofiber skin dressing (Spincare matrix) to help heal wounds in people with recessive dystrophic epidermolysis bullosa (RDEB), a rare genetic condition causing fragile, blistering skin. Six participants aged 6 and old…

This study tested a procedure called cryoablation, which uses cold to numb nerves around broken ribs, to help elderly patients manage pain. The goal was to reduce complications and help them get back to normal activities faster. 127 patients over age 65 with rib fractures took pa…

This study looked at 159 adults who had nose surgery (rhinoplasty) to see which pain medicine worked better for the first 5 days after surgery. One group took a combination of acetaminophen and hydrocodone, while the other took acetaminophen and ibuprofen. Participants rated thei…

This study aimed to raise awareness about alcohol flushing and its link to cancer in Asian communities. 70 participants received a cheek swab to test their ALDH2 gene and completed questionnaires about their drinking habits. The goal was to see if learning their genetic risk woul…

This study tested whether routinely asking heart failure patients a 12-question survey about their symptoms and quality of life during clinic visits leads to better care. Over 1,200 participants were randomly assigned to start the survey right away or after a one-year delay. Rese…

This completed Stanford study looked at how ketamine changes activity in brain areas linked to reward and risk. Thirteen healthy adults who had used ketamine before underwent brain scans while performing tasks. The goal was to understand ketamine's effects on brain circuits, not …

This study looked at how a reading program called Seeing Stars changes the brains of 90 children with dyslexia. Using brain scans, researchers measured changes in brain wiring and reading skills. The goal was to understand why some children improve more than others, which could l…

This study tested a new way to target brain stimulation for depression. 50 adults with major depression received a single session of transcranial magnetic stimulation (TMS) aimed at their individual brain networks. The goal was to see if personalized targeting could improve brain…

This study looked at whether children and teens who had a stem cell transplant for leukemia could use an iPad-based brain-training program. The main goal was to see if the program was practical and if kids would stick with it. Only 17 participants were enrolled, and the study foc…

This study looked at how reliably a new imaging tracer called [18F]-FTC-146 shows up in the brain. Five healthy adults aged 18-65 had brain scans and blood tests to see if the tracer's uptake is stable and reproducible. No treatment was given; the goal was simply to understand th…

This study tested a new micro-ultrasound system to see if it can better find and outline prostate cancer. Researchers took detailed ultrasound images from 95 men before biopsy or surgery and compared them to standard tests and tissue samples. The goal is to develop more accurate …

This study looked at 233 people with heart or blood vessel disease who had calcium buildup in their heart arteries found by chance on a chest CT scan. Researchers wanted to see if telling both the patient and their doctor about this finding would encourage them to start cholester…

This study collected genetic samples from over 1,000 adults with Neurofibromatosis Type 1 (NF1) to find why some develop many skin neurofibromas while others have few. Researchers analyzed DNA to identify common gene variants linked to tumor growth. The goal is to better understa…

This completed trial tested whether a short animated storytelling video could reduce stigma toward people with addiction. Over 13,000 adults from multiple countries watched the video online and answered questions about their attitudes. The goal was to see if the video could boost…

This study looked at whether a gentle brain stimulation technique called rTMS could reduce abnormal electrical activity in the brains of children with a common form of epilepsy. The researchers wanted to see if this could also improve language and learning issues that often come …

This study compared a low-cost, low-intensity egg freezing protocol (fewer doctor visits and injections) to the standard high-intensity approach. Researchers looked at how many eggs were retrieved, patient satisfaction, and overall cost. The goal is to see if a simpler, cheaper m…

This study tested different doses of a brain stimulation technique called TMS in 48 people with treatment-resistant depression. The goal was to see how the stimulation changes brain connections and how that relates to mood. Half got real stimulation, half got a fake version, and …

This Stanford study explores how brain circuits relate to anxiety and depression. 167 participants with recent symptoms (no diagnosis needed) undergo brain scans and cognitive tests. Some also receive a 12-week course of pramipexole medication or rTMS therapy. The goal is to unde…

This completed Stanford study looked at whether video-recorded facial expressions and speech patterns can reflect a person's mood. Eleven adults with depression or epilepsy had electrodes temporarily placed in their brains to record brain activity. Researchers stimulated certain …

This study looked at whether offering rewards—like money for yourself or donations to others—can increase daily steps in adults aged 18 and older. Researchers compared how young, middle-aged, and older adults responded to these incentives. The goal was to learn which types of rew…

This study looked at 115 adults with prediabetes to understand why different people develop the condition. Researchers tested how each person's body responds to different foods, aiming to create personalized diet plans that prevent diabetes. The goal was to find biological marker…

This study looked at whether a vibrating device can distract from the pain of a needle prick. Two hundred healthy adults took part. They received light pinpricks with and without the vibrating device, and rated their pain and anxiety. The goal was to see if vibration helps lower …

This study looked at how MDMA affects brain circuits related to risk and reward. Twenty-two healthy adults who had used MDMA before took part. Researchers used brain scans to measure brain activity while participants viewed faces and at rest. The goal was to understand how MDMA c…

This study tested whether electronic alerts can help anesthesia providers reduce the amount of fresh gas they use during surgery. Over 300 anesthesia providers participated. The goal was to see if these alerts lead to lower gas flow rates, which can save money and reduce environm…

This study tested whether playing recordings of a mother's voice to preterm babies in the NICU helps their brain and language development. Researchers enrolled 57 preterm infants born between 24 and 31 weeks. The goal was to see if this simple, non-invasive intervention could imp…

This study looked at whether notifying patients and their doctors about calcium buildup in the heart arteries (found by chance on a chest CT scan) leads to better heart health. About 200 adults were randomly assigned to receive this notification or usual care. The main goal was t…

This study followed nearly 10,000 college students over several years to understand how friendships, daily moods, and brain activity relate to anxiety, depression, loneliness, and stress. Participants completed surveys and some underwent brain scans. The goal was to learn more ab…

This study looked at gene activity in prostate tissue from 867 men to better understand how prostate cancer develops and grows. Researchers compared genetic information with patient health records to find links between genes and cancer outcomes. The goal was to learn more about t…

This study looked at how a diabetes medicine called ertugliflozin affects fat tissue around the heart. Researchers took fat samples from 61 adults with type 2 diabetes and heart disease during heart surgery. They tested the fat in a lab to see if the drug improved how the fat cel…

This study tested a new way to treat depression that doesn't respond to medication. Researchers used a brain stimulation technique called rTMS, but with a twist: they monitored brain activity in real time to adjust the stimulation for each person. 44 adults with medication-resist…

This study looked at whether a genetic marker called COMT can predict how well a person responds to hypnosis for pain after surgery. Researchers tested a new, faster method to read this gene from saliva or blood samples. The goal is to one day use a simple genetic test to persona…

This study tested whether heart failure patients learn more from watching videos or reading text about their condition. 130 patients with heart failure took part. They were randomly assigned to video or text modules, then tested on their knowledge. The goal is to find the best wa…

This study looked at the different types of cells inside breast tumors to better understand how they affect treatment response. Researchers used advanced molecular tools to analyze samples from 145 people with breast cancer. The goal was to gather knowledge that could lead to bet…

This study looked at how different types of virtual reality (VR) games affect pain perception in 265 healthy adults. Participants played both passive and active VR games while researchers measured their heat and pressure pain thresholds. The goal was to understand if the type of …

This study looked at whether warning labels on social media can discourage teens and young adults (ages 13-29) from using it. Over 1,000 participants rated how effective different warning messages were. The study also tested if warnings improved by artificial intelligence worked …

This completed study surveyed over 500 breast cancer patients from low-income and minority groups in Northern California to find out what stops them from getting genomic testing. Researchers used an online survey and phone interviews to gather information. The goal was to identif…

This study tested whether a mixed reality simulation could increase empathy in anesthesiology trainees. 81 participants completed empathy surveys before and after the immersive experience. The goal was to see if this type of training could help future doctors better understand th…

This study tested whether showing health or climate labels (or both) and suggesting healthier or more eco-friendly food swaps in an online grocery store helps people make better choices. Over 1,200 adults in the U.S. shopped in a simulated online store, and researchers measured t…

This study tested a digital health program called Bladder Basics for children aged 5-10 with bladder issues. Researchers measured how many families joined, watched the videos, and completed follow-up surveys. The goal was to see if this approach could work in schools to improve b…

This study from Stanford University looked at how the immune system responds to exercise and whether it plays a role in delayed onset muscle soreness (DOMS). Twenty-two healthy adults did arm exercises and gave blood samples over several days. Researchers measured immune markers …

This early-phase study at Stanford looked at how a nutritional supplement called alpha-ketoglutarate is absorbed into the eyes when taken orally. Seventeen adults with age-related eye diseases participated. The main goal was to measure changes in the supplement's level in eye flu…

This study tested whether having spine surgery patients wear an Apple Watch could help doctors track their recovery. 255 adults wore the watch before and after surgery to measure steps and distance. The goal was to see if this data matched how patients felt and if it could improv…

This study tested whether a dye called fluorescein sodium, given through an IV, can help surgeons identify nerves during head and neck surgery. Eight adults having open head and neck surgery took part. The goal was to see if the dye makes nerves glow, potentially reducing nerve d…