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Family support boosts opioid treatment success

NCT ID NCT04239235

Disease control Sponsor: Stanford University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding a support person—like a family member or friend—to standard buprenorphine treatment helps people with opioid addiction stay in treatment longer. 439 patients and their support persons took part. The support persons learned CRAFT, a counseling program that teaches them how to encourage their loved one's recovery. The main goal was to see if patients stayed on buprenorphine for at least 6 or 12 months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
buprenorphine/naloxone
What this could lead to
If successful, this approach could improve treatment retention and reduce opioid use for people with opioid addiction.
What could go wrong
This is a completed study, but results may not apply to all settings. The intervention relies on having a willing support person, which not everyone has.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

439 people

The number who actually took part.

Started

Feb 2021

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Patient inclusion criteria: * 18 and older * on buprenorphine treatment for OUD * has an eligible support person that participates Support person inclusion criteria: * 18 and older * frequent contact with the patient * willing and available to try CRAFT Patient exclusion criteria: * \< 18 years and older * not currently receiving buprenorphine * not able to provide consent Support person exclusion criteria: * \< 18 years and older * currently has a problem with heroin or opioid pills * not able to provide consent * actively using other substances such that their presence in group would be contraindicated

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Conditions

The condition(s) this trial relates to.

opiate dependence opioid abuse

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Opioid addiction

Contacts and locations

Locations

  • Behavioral Health Services

    Gardena, California, 90249, United States

  • Contra Costa Health Services

    Concord, California, 94553, United States

  • Family Health Centers of San Diego

    San Diego, California, 92110, United States

  • Lifelong Medical Care

    Berkeley, California, 94703, United States

  • Open Door Community Health Centers

    Arcata, California, 95521, United States

  • Venice Family Clinic

    Venice, California, 90291, United States

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