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Brain scans reveal how reading rewires dyslexic Kids' brains

NCT ID NCT04323488

Knowledge-focused Sponsor: Stanford University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how a specific reading program, called Seeing Stars, affects the brains of 90 children with dyslexia. Researchers used brain scans to measure changes in white matter and a region linked to word recognition. The goal was to understand why some children improve more than others, which could lead to more personalized dyslexia treatments in the future.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Lindamood-Bell Seeing Stars reading program
What this could lead to
If successful, this research could point toward more personalized reading interventions for children with dyslexia based on brain changes.
What could go wrong
This is a small, completed study focused on understanding brain mechanisms, not testing a treatment. Results may not lead to immediate practical changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

90 people

The number who actually took part.

Started

May 2021

Finished

Sep 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

8 to 12 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Reading difficulties defined as low scores on standardized measures of reading skills Exclusion Criteria: * no major contraindication for MRI (braces, metal implants, pacemakers, vascular stents, or metallic ear tubes). * Because the study involves measurements of reading and language ability, new recruits will be native English speakers. * Subjects have no history of neurological disorder, significant psychiatric problems * exclude claustrophobic subjects since an MRI might be uncomfortable for them.

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Conditions

The condition(s) this trial relates to.

dyslexia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dyslexia, developmental

Contacts and locations

Locations

  • Stanford University

    Stanford, California, 94305, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.