Stanford University

This pilot study from Stanford University is testing whether providing non-alcoholic beer or sparkling water to people being treated for alcohol use disorder is acceptable and feasible. Sixty participants in California who are already in a treatment program will receive one of th…

This study follows 1,500 patients with multivessel coronary artery disease who were randomly assigned to receive either coronary stenting guided by fractional flow reserve or coronary bypass surgery. Researchers will compare survival, quality of life, and chest pain relief over 1…

This study tests whether giving heated chemotherapy directly into the abdomen during surgery can lower the chance of uterine leiomyosarcoma coming back. 17 adults with a local recurrence of this rare cancer are participating. The approach combines surgery to remove visible cancer…

This early-phase study tests whether adding special immune cells to a standard islet transplant can help people with severe type 1 diabetes better control their blood sugar. Participants will receive either their own regulatory T cells or donor bone marrow cells along with the tr…

This study tests whether a short course of radiation (1 to 5 days) after breast cancer surgery is as safe and effective as the standard 6.5-week treatment. It includes women aged 40 and older with small tumors who choose lumpectomy. The goal is to see if shorter radiation reduces…

This study looks at whether a single dose of antibiotics given during nose surgery works just as well as taking a full course of antibiotics afterward to prevent infections. About 864 adults having nose surgery will take part. The goal is to find out if the shorter antibiotic app…

This study looks at whether a special program that uses smartphones and community feedback can help older women who are not very active to walk more. About 232 women from across the U.S. will take part. The goal is to see if this approach, combined with basic activity tips, works…

This study tests a drug called QBS72S in 21 adults with breast or lung cancer that has spread to the brain. The drug is given once a month through an IV. The main goal is to see if it shrinks brain tumors. The trial is active but not recruiting new participants.

This early-phase study tests whether adding pulses of the cancer drug dasatinib can improve CAR T-cell therapy (brexucabtagene autoleucel) for adults with relapsed or refractory B-cell acute lymphoblastic leukemia. Eight participants will receive dasatinib on a weekly 3-day sched…

This study tests whether long-term, mild electrical stimulation using a home device can safely slow vision loss in people with open-angle glaucoma. About 45 adults with moderate vision damage will use the device regularly. The goal is to see if this approach can protect the optic…

This study tests a special nail made from a material that integrates with bone to treat a type of knee fracture. Ten people with knee pain lasting at least 3 months will receive the nail during knee surgery. The goal is to see if the nail improves pain and function.

This study tests a new treatment for glaucoma, a disease that damages the optic nerve and can lead to blindness. Researchers implant tiny capsules that release a protein to protect nerve cells. Thirty people with moderate to advanced glaucoma will receive either the implant or a …

This early-stage study tests a treatment that uses a patient's own immune cells, modified to recognize and attack cancer cells, for adults with B-cell blood cancers that have returned or not responded to standard therapy. The treatment is given with chemotherapy and sometimes an …

This early-phase study tests a stem cell transplant method for people with advanced blood cancers like leukemia. Instead of using strong drugs to prevent complications, doctors give specially selected immune cells (regulatory T-cells) along with regular T-cells to help the body a…

This study tests whether advanced CT imaging can help doctors plan better coronary bypass surgery for 200 people with heart disease. Participants get a CT scan before and after surgery to measure blood flow changes. The goal is to improve surgical decisions and reduce chest pain,…

This study tests an experimental pill, VK 2019, that blocks a protein the Epstein-Barr virus uses to grow cancer cells. It is for people with nasopharyngeal cancer or other EBV-related cancers that have come back or spread and have no standard treatments left. The main goal is to…

This study tests a tiny implant that releases cells to protect the optic nerve in people with glaucoma. 54 participants receive either the implant or a sham procedure. The main goal is to see if it slows vision loss over 6 months. This is an early-phase trial, so the focus is on …

This study tests the drug pembrolizumab (Keytruda) in 12 people with advanced anaplastic thyroid cancer that cannot be cured by standard treatments. The goal is to see if the drug can shrink tumors or stop them from growing. Participants receive the drug every 3 weeks until the c…

This study compares two types of corneal transplant surgery (UT-DSAEK and DMEK) in 160 people with Fuchs dystrophy, a condition that clouds the cornea. It also tests whether a drug called rho-kinase inhibitor can reduce loss of important eye cells after surgery. The goal is to fi…

This study tests whether offering financial rewards can help people with schizophrenia, bipolar disorder, or substance use disorder stick to their long-acting injectable medication after being forced into the hospital. About 1,000 participants will be randomly assigned to receive…

This early-stage trial tests whether giving specially engineered donor immune cells (CAR T cells) after a stem cell transplant is safe for adults with a high-risk type of B-cell leukemia. About 22 participants will receive the treatment to see if it can help prevent the cancer fr…

This study looks at whether remotely monitoring continuous glucose monitor (CGM) data can improve diabetes management in children within the first year after diagnosis. About 100 kids and teens newly diagnosed with type 1 diabetes will have their CGM data shared with their care t…

This study was designed to compare two ways to treat walled-off necrosis (a pocket of dead tissue) caused by severe pancreatitis. One method uses a scope through the mouth to clean out the pocket, the other uses surgery through the stomach. The goal was to see which approach work…

This study tests whether a nerve block in the neck can increase blood flow to the brain in people who develop narrowed blood vessels after a bleeding stroke. Ten adults in the ICU will receive the block, and researchers will measure changes in blood flow and neurological function…

This study tests a type of radiation called high-dose brachytherapy for men with prostate cancer that hasn't spread. Doctors place tiny radioactive sources directly into the prostate to deliver a strong dose to the tumor while sparing nearby healthy tissue. The goal is to control…

This study tests a new 3D body scanner called NSite for monitoring adolescent idiopathic scoliosis. Researchers want to see if the device gives the same results when used by different people. The study involves 13 teens aged 10-18 who are being evaluated for scoliosis. If success…

This study explores whether special ultrasound techniques can detect early signs that cancer immunotherapy is working. Researchers will scan tumors in 30 adults with solid tumors before and after three weeks of treatment. The goal is to see if changes in blood flow measured by ul…

This study tests a new imaging agent called 111In-panitumumab to see if it can safely and accurately find cancer spread in lymph nodes of people with head and neck cancer. About 28 participants will receive the agent before surgery, and its ability to detect cancerous lymph nodes…

This early-stage study is testing a radioactive imaging agent called [18F]-C-SNAT4 to see how it travels through the body and whether it can help detect lung cancer on PET scans. About 20 healthy volunteers and people with lung cancer will receive the tracer and undergo scans. Th…

This study planned to use online tools like ads and social media to encourage safer sun habits and reduce skin cancer risk. It was designed for men aged 18-65 who use Facebook and are interested in LGBT topics. However, the study was withdrawn before any participants were enrolle…

This study tests whether replacing dirt floors with concrete in rural Bangladeshi homes can reduce infections in children. About 800 pregnant women and their future babies will take part, with children checked for parasites and diarrhea up to age 2. If concrete floors lower infec…

This study tests whether encouraging water over sugary drinks in childcare centers can help prevent obesity in preschool-age children. The program includes better access to healthy drinks, lessons for kids, and counseling for families. Researchers are tracking 882 children to see…

This study tests a free online program called Healthy Futures: Alternative-to-Suspension, designed to teach high school students about the risks of tobacco and nicotine and provide resources to quit. About 2,540 students from schools that agree to use the program or continue thei…

This study compares two types of spinal cord stimulation—high frequency and burst—for people with chronic back or leg pain. Researchers will track pain relief and function over at least 36 months using patient surveys. The goal is to help doctors decide which waveform works best …

This study tests whether a single dose of ketamine, given while patients are sedated, can help with chronic pain and depression. Forty adults with both conditions will receive either ketamine or a placebo (saline) during propofol sedation. Researchers will track pain and depressi…

This study tested whether listening to spatial audio (a type of immersive sound) could help people tolerate heat pain better. Healthy adults would have a heat device placed on their hand and rate their pain with and without the audio. The study was withdrawn before any participan…

This study tests a web-based decision aid called 'Roadmap to Parenthood' for young women who have completed cancer treatment and are thinking about having children. The tool provides information and planning support to help them make informed choices. Researchers will measure whe…

This pilot study tests whether virtual reality (VR) therapy can reduce depressive symptoms in pregnant women who are hospitalized for complications. 44 participants will either receive VR-enhanced behavioral activation therapy or standard social work consultation for 3 weeks. The…

This study tests whether a smartphone app called Stanford SpineKeeper can help people with chronic low back pain feel better and move more easily. The app provides a personalized lifestyle program and tracks pain, steps, and activity. The goal is to improve quality of life withou…

This study tests whether a single pain relief skills session, called Empowered Relief, can lower the chance of long-term pain after a cesarean delivery. About 60 women who still have moderate to severe pain 6 weeks after their C-section will take part. The session teaches simple …

This study tests whether a computer-based AI tool can teach glaucoma patients how to take a visual field test more accurately. The test checks side vision, which is important for monitoring glaucoma. If the tool works, it could lead to more reliable results, fewer repeat visits, …

This study planned to test whether an augmented reality (AR) app called Reia could help stroke survivors with arm weakness do rehab exercises at home. Participants would have used an AR headset for daily 30-minute sessions over 8 weeks, with weekly video check-ins from a therapis…

This study tests whether a live, online exercise program can improve physical function in adults waiting for a kidney transplant. Eighty participants will either join twice-weekly virtual exercise sessions or a health education class. The main goal is to see if they can stand up …

This study tests whether a nurse-led supportive care program can improve symptoms and quality of life for people with mild cognitive impairment or dementia living at home. Over 12 months, nurses will assess needs and coach patients, while tracking caregiver burden and advance car…

This study tests whether adding a blood flow restriction (BFR) cuff to low-weight hand exercises can help people with ulnar-sided wrist pain recover faster. 90 adults will be assigned to either standard therapy or therapy plus BFR. The goal is to see if BFR improves grip strength…

This study tests a prescription cream (clascoterone) to treat acne caused by testosterone therapy in transgender men. About 18 participants will use the cream daily for 3 months to see if it reduces pimples without affecting their hormone levels. The goal is to provide a safe acn…

This study tests a special audio-visual system called AVATAR to help children aged 3 to 10 stay still during radiotherapy without needing anesthesia. The goal is to see how many kids can complete at least one treatment session without anesthesia. If successful, this could make tr…

This study compares two pain management methods for adults with broken ribs: a continuous lidocaine drip into a vein versus a nerve block (ESP block) near the spine. The goal is to see which provides better pain control and helps patients breathe deeper. The study was withdrawn b…

This study tests whether a special silicone dressing (Neodyne embrace) can improve the appearance of abdominal scars in women who had breast reconstruction using tissue from their belly. Thirty women will have part of their incision treated with the dressing and the other part le…

This study tests a quick, non-invasive brain stimulation method called accelerated intermittent theta-burst stimulation (aiTBS) to see if it can improve mood in people with borderline personality disorder (BPD) who are also experiencing a major depressive episode. About 45 adults…

This study tests whether a physical activity program can improve mood and reduce stress in pregnant people who have symptoms of depression or anxiety. About 88 participants will be randomly assigned to either the exercise program or usual care. The main goal is to see if the prog…

This study looks at whether a special pain relief skills session (called Empowered Relief) and educational videos can improve recovery for women after a cesarean delivery. About 60 women will take part, and researchers will measure how many sign up and attend the session, how sat…

This study is testing a new device that uses gentle vibrations on the belly, back, or temples to help people with chronic pain conditions like pelvic pain, abdominal pain, low back pain, or migraine. About 50 adults will try the real device or a placebo to see if it safely reduce…

This study looks at whether N-acetylcysteine (NAC), a well-tolerated nutritional supplement, can reduce restricted and repetitive behaviors in children with autism spectrum disorder. About 144 children who previously took part in related NAC trials will receive the supplement and…

This study aimed to see if putting up fake windows that show outdoor scenes could improve the mood of teachers working in classrooms without real windows. It was planned for teachers at one school in New York, but the study was withdrawn before any teachers joined. No results are…

This study tests a small vibrating device held near the skin during needle sticks (like IVs or blood draws) to see if it lowers pain and anxiety. About 1,100 children and adults will take part. Researchers will watch and ask about discomfort to see if the buzz helps people feel c…

This study aimed to see if having a parent appear on a video call during anesthesia induction could reduce children's anxiety as effectively as the sedative midazolam. It was designed for children aged 4 to 8 undergoing outpatient surgery. However, the study was withdrawn before …

This small study tested whether a non-invasive brain stimulation technique called tDCS can be used safely at home to reduce seizures in people with epilepsy. Four adults with hard-to-control seizures used the device daily for several weeks. Researchers tracked seizure counts, sev…

This study looked at whether a bioactive fabric sleeve can reduce arm soreness in college baseball players after pitching. Thirteen players from Stanford wore the sleeve and rated their soreness the next day. The goal was to see if the sleeve helps muscles recover better than a r…

This study aimed to see if adding nitrous oxide (laughing gas) to standard sedation during GI endoscopy (like colonoscopy) could reduce side effects such as fatigue, mental fogginess, and nausea after the procedure. The study was designed for adults 18 and older undergoing these …

This early-phase study at Stanford University is looking at whether the medication droperidol can change how much people like other drugs given during surgery or procedures. About 130 participants will rate their drug liking and sedation levels, and researchers will also measure …

This study tests whether a simple questionnaire, filled out by children, teens, and their caregivers before and after a clinic visit, can help doctors better understand symptoms. About 85 participants will use the tool during routine appointments. The goal is to see if it's pract…

Stanford University is developing a mobile app that uses video recordings of a simple physical test (the Short Physical Performance Battery) to assess mobility and cognitive function in older adults. The study involves 30 healthy adults aged 18+ who will perform the test once whi…

This pilot study aimed to test a new breast-dedicated PET camera that can see details as small as 1 millimeter. Researchers planned to inject a radioactive tracer into people with breast cancer and see if the camera could produce clear images. However, the study was withdrawn bef…

This Stanford study is testing whether non-intrusive sensors placed in the home can automatically track neuropsychiatric symptoms like mood changes and agitation in older adults. Researchers will enroll 25 participants with or at risk of mild cognitive impairment or dementia, alo…

This Stanford study compares high-intensity interval training (HIIT) with moderate-intensity continuous training (MICT) in 135 healthy but sedentary adults. Over 12 weeks, participants will exercise three times a week for about an hour. Researchers will measure changes in fitness…

This study aims to find biological markers that can tell if a person with chronic muscle or joint pain will get better or keep having severe pain and disability. Researchers will follow 250 adults aged 18-80 to track their pain and function over time. The goal is to improve diagn…

This study aimed to see if conversational AI simulations could help anesthesiology trainees improve their communication skills for difficult talks, like telling a patient about a medical error. It planned to include healthcare workers who talk with patients daily. However, the st…

This study collects blood and tissue samples from people receiving or donating bone marrow transplants for leukemia, lymphoma, or other blood diseases. Researchers will analyze these samples to find genes and proteins linked to cancer development and transplant complications. The…

This study was designed to see if a new type of airway device can prevent dangerous drops in oxygen levels during anesthesia in patients who are at high risk, such as those with obesity or sleep apnea. Researchers planned to compare the new device with standard ones in adults und…

This study aimed to see if changing how cancer patients think about their illness could improve their quality of life and treatment outcomes. Researchers planned to follow newly diagnosed patients and give some a short mindset training. However, the study was withdrawn before any…

This study tests whether a new type of imaging called Deuterium Metabolic Imaging (DMI) can predict how well glioblastoma patients respond to treatment. Ten participants will drink a special sugar solution before scans to see how their tumors process glucose. The goal is to find …

This study tests whether an AI-powered speech-to-text tool can accurately capture health information from heart failure patients. Researchers at Stanford will enroll 100 adults with heart failure to see if the tool's summaries match expert reviews. The goal is to improve communic…

This study planned to use Apple Watches to track physical activity, diet, and environment in children with complex regional pain syndrome (CRPS) to identify what triggers sudden severe pain. However, the study was withdrawn before enrolling any participants, so no data was collec…

This pilot study aimed to see if personalized lifestyle coaching and a simple handout could help emergency medicine residents stay alert and perform better during night shifts. The study planned to compare coached residents to those receiving only a handout, measuring reaction ti…

This study looks at whether giving pharmacists extra education plus monthly feedback on their performance helps them adjust heart failure medications more often than just education alone. About 400 pharmacists across 22 VA sites will take part. The goal is to see if simple change…

This study is creating a large database of information from 250 older adults (65+) having surgery with general anesthesia. Researchers collect blood samples, brain wave recordings, and memory tests before and up to a year after surgery. The goal is to find patterns that could hel…

This study looks at whether using a mild electrical current (neurostimulation) along with ultrasound can make nerve blocks work better for people having arm surgery. About 82 adults will be enrolled to see if the stimulation speeds up numbness and improves pain control. The goal …

This study aimed to help 4th graders develop healthy bladder habits by providing education, water stations, and changes to classroom bathroom policies. Researchers planned to track bathroom use, symptom scores, and urine volume. However, the study was withdrawn before enrolling a…

This study was designed to learn why some children with type 1 diabetes, especially those with public insurance, do not use helpful diabetes technology like continuous glucose monitors. Researchers planned to interview and survey healthcare providers to understand barriers and fi…

This study looks at whether brain scans can help predict which veterans with hard-to-treat depression will get better with a treatment called transcranial magnetic stimulation (TMS). Researchers will use MRI scans to measure brain activity before and during TMS therapy. The goal …

This study tests whether focused ultrasound to the brain can change how the anesthetic propofol works. Ten healthy adults will receive both real and fake ultrasound while under sedation. Researchers will measure brain signals and response times to see if ultrasound alters anesthe…

This study looks at how eating fermented and fiber-rich foods during pregnancy changes the gut bacteria of mothers and their babies. Researchers will track 135 pregnant women and their infants to see if diet affects the types of bacteria passed from mom to baby. The goal is to le…

This study looks at 600 adults with non-compaction cardiomyopathy, a rare heart muscle condition that can lead to heart failure, stroke, or dangerous heart rhythms. Researchers will use heart scans, genetic tests, and health records to find better ways to predict who is at highes…

This study aimed to compare how much the bicep tendon moves after surgery using either one standard anchor or two mini anchors. Participants would have had a small marker placed on the tendon and X-rays taken right after surgery, at 2 weeks, and at 6 months. However, the study wa…

This study aimed to see if telling patients and their doctors about calcium buildup in heart arteries (found on lung cancer scans) would lower the chance of death, heart attack, or stroke. It was designed for adults without known heart disease who had a lung scan showing signific…

This study looks at how fentanyl changes brain activity using EEG (a brain wave test) in 20 adults having surgery. Researchers want to find a specific brain signal linked to fentanyl and see if it relates to how much people like the drug. No new treatment is tested—only brain pat…

This study aimed to find out if removing the nail plate helps people with nailbed injuries heal better. It planned to track complications, pain, appearance, and hand function over time. However, the study was withdrawn before enrolling any participants, so no results are availabl…

This study tests whether artificial intelligence (AI) can help medical interns learn how to use ultrasound machines more quickly and accurately. About 150 internal medicine residents will be split into two groups: one group uses a handheld ultrasound device with AI assistance, th…

This study aimed to see if a fast-acting form of brain stimulation (called accelerated TMS) could change brain activity linked to suicidal thinking in adults hospitalized for major depression. The researchers planned to measure changes in suicidal thoughts using a standard questi…

This study looks at whether fixing sleep problems can help with mood and behavior issues like anxiety, agitation, and depression in people with early Alzheimer's or mild cognitive impairment. About 150 adults aged 50-90 with sleep troubles and mild mood symptoms will get either a…

This research study collects blood, tumor tissue, and other body fluids from 1,000 adults with lung cancer, thymus cancer, or mesothelioma. The goal is to analyze these samples to find biological markers that could predict how the disease will progress or which treatments might w…

This study aimed to see if a mobile monitoring tool could accurately identify surgical site infections (SSIs) in orthopedic surgery patients, compared to the usual manual review. The study was withdrawn before enrolling any participants, so no results are available. It was design…

This study follows 275 teens aged 11-18 with chronic muscle or joint pain to find clues that predict who will get better and who will have lasting pain. Researchers measure pain levels and daily function over time. The goal is to improve treatment by identifying early markers of …

This study tests whether digital programs can improve the health, wellbeing, and daily functioning of people recently diagnosed with cancer. About 440 participants will be randomly assigned to one of two online courses, complete questionnaires, and provide blood samples at home. …

This study aims to identify brain-based subtypes of Obsessive-Compulsive Disorder (OCD) and see how they respond to two different targets of repetitive transcranial magnetic stimulation (rTMS). Researchers will use brain scans to measure connectivity in specific networks before a…

This study looks at how two parts of the thalamus (ANT and PLV) are connected to other brain areas and how they are involved in seizures and memory. Researchers will record brain activity from 100 epilepsy patients who already have electrodes implanted for medical reasons. The go…

This study at Stanford University is testing whether wearable devices can help measure fatigue, sleep, and daily activity in people with primary biliary cholangitis (PBC). About 30 participants will wear a device and answer questionnaires to see if changes in body data match chan…

This study aimed to see if notifying patients and their primary care doctors about calcium buildup in heart arteries (found on a prior chest CT) would increase the number of people starting cholesterol-lowering statins. It planned to include adults aged 18-84 with moderate to sev…

This study tests a program called Tap Trust that aims to help families feel better about their home tap water. Researchers want to see if it increases how much water preschool-aged children and their parents drink. About 100 families are taking part.

This study looks at whether a parent coaching and family navigation program (Project AFECT) can help families right after a child is diagnosed with autism. About 200 parents of children aged 1 to 5, who are Hispanic/Latino, Black/African-American, or have Medi-Cal insurance, will…

This study tests whether a custom AI chatbot can help cataract patients better understand their artificial lens choices before meeting their surgeon. About 70 adults will either get standard counseling or standard counseling plus an AI explanation. The goal is to see if the AI to…

This study aimed to see if anesthesiology residents in Hong Kong could use augmented reality (AR) to practice crisis skills with experts in the United States. The focus was on non-technical skills like teamwork and decision-making. However, the study was withdrawn before any part…

This early-stage study at Stanford University compares ketamine to a placebo (saline) during sedation in 15 healthy adults with major depressive disorder. The goal is to see how these drugs affect brain activity and experiences like dreams or thoughts. Researchers will use EEG to…

This study looks at how immune cells in different types of body fat (belly fat vs. fat under the skin) are linked to insulin resistance, a condition where the body doesn't use insulin well. Researchers will analyze fat samples from 50 people having weight-loss surgery to see if c…