New pill could ease arm swelling in lymphedema patients
NCT ID NCT05203835
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 34 times
Summary
This study tested a daily pill called acebilustat in 40 adults with arm lymphedema (swelling from poor lymph drainage). Participants took either the drug or a placebo for 9 months. Researchers measured changes in skin thickness and arm structure to see if the drug helps reduce swelling.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
-
Stanford University
Palo Alto, California, 94305, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
acebilustat (a daily pill)
What this could lead to
If it works, this could point toward a new daily pill to reduce arm swelling and skin thickening in people with lymphedema.
What could go wrong
This is a small, early-phase trial with only 40 people. The drug may not improve lymphedema better than placebo, and side effects are possible.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.