Could a daily pill reduce arm swelling? new trial tests acebilustat
NCT ID NCT05203835
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a daily pill called acebilustat in 40 adults with long-term arm lymphedema (stage 2, lasting over 6 months). Participants took either the drug or a placebo for 9 months, with the first 3 months on placebo for all. The main goal was to see if the drug reduces skin thickness in the affected arm. Researchers also measured changes in arm volume and structure using ultrasound.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Acebilustat (a daily oral capsule)
- What this could lead to
- If it works, this could point toward a new daily pill to reduce arm swelling and skin thickness in people with lymphedema.
- What could go wrong
- This is a small, early-phase trial with only 40 people. The drug may not reduce swelling better than placebo, and long-term safety is not yet known.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Stanford University
Palo Alto, California, 94305, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.