New program aims to prevent lymphedema in breast cancer patients

NCT ID NCT06144164

Recruiting now Prevention Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a comprehensive program can prevent lymphedema (chronic arm swelling) in women undergoing lymph node removal for breast cancer. The program includes immediate lymphatic reconstruction during surgery, self-directed lymphatic massage, and regular arm measurements. Researchers will compare arm volume changes over time to see if the program reduces lymphedema risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Immediate Lymphatic Reconstruction (ILR) surgery, lymphatic massage, and regular arm measurements
What this could lead to: If successful, this program could become a standard way to prevent chronic arm swelling after breast cancer surgery, improving quality of life for many women.
What could go wrong: This is a relatively small, single-center trial, and the prevention program is complex. It may not work for everyone, and there are surgical risks from the lymphatic reconstruction procedure.

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Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma breast neoplasm female breast carcinoma lymphedema prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER BREAST CARCINOMA FEMALE BREAST CANCER LYMPHEDEMA LYMPHEDEMA ARM LYMPHEDEMA OF UPPER ARM

Contacts and locations

Locations

Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
RECRUITING

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Bergen (Limited Protocol Activities)
RECRUITING

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
RECRUITING

New York, New York, 10065, United States
Memorial Sloan Kettering Commack (Limited Protocol Activities)
RECRUITING

Commack, New York, 11725, United States
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)
RECRUITING

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Nassau (Limited Protocol Activities)
RECRUITING

Uniondale, New York, 11553, United States
Memorial Sloan Kettering Westchester (Limited Protocol Activities)
RECRUITING

Harrison, New York, 10604, United States

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