Freezing away pain: new procedure could replace opioids for broken ribs
NCT ID NCT05330611
First seen Feb 04, 2026
Summary
This study tested a procedure called cryoneurolysis, which uses a device to freeze nerves near broken ribs to block pain. It involved 43 adults aged 18-64 with rib fractures who were not candidates for surgery. The goal was to see if this approach could lower pain scores and reduce the need for strong painkillers like opioids.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Stanford Hospital and Clinics
Palo Alto, California, 94305, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cryoneurolysis (cold nerve block using Iovera device)
What this could lead to
If it works, this could offer a non-surgical way to control rib fracture pain and reduce reliance on narcotics.
What could go wrong
This was a small, early study with only 43 participants. Results may not apply to everyone, and the procedure carries risks like nerve damage or incomplete pain relief.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.