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Home workouts boost fitness in kids with single ventricle hearts

NCT ID NCT04195451

First seen Apr 26, 2026 · Last updated Jun 20, 2026 · Updated 9 times

Summary

This study tested whether a live-video-supervised exercise program could improve fitness in children and teens (ages 8-19) born with a single ventricle, a condition often treated with the Fontan procedure. Participants exercised three times a week for three months, then a maintenance phase. The goal was to see if this approach could safely boost exercise capacity, muscle strength, and overall health, potentially lowering the risk of heart failure later in life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Stanford University, Lucile Packard Children Hospital

    Palo Alto, California, 94304, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

live-video-supervised exercise (aerobic + resistance training)

What this could lead to

If it works, this could lead to a safe, home-based exercise program that improves fitness and muscle health in children with Fontan circulation, potentially reducing long-term heart failure risk.

What could go wrong

This is a completed trial, but it was relatively small (150 participants) and focused on short-term fitness gains. It may not prove that exercise reduces death or need for transplant, and results may not apply to all Fontan patients.

Conditions

The condition(s) this trial relates to.

univentricular heart

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.