Home workouts boost fitness in kids with single ventricle hearts

NCT ID NCT04195451

Completed Symptom relief Sponsor: Stanford University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a live-video-supervised exercise program could improve fitness in children and teens (ages 8-19) born with a single ventricle, a condition often treated with the Fontan procedure. Participants exercised three times a week for three months, then a maintenance phase. The goal was to see if this approach could safely boost exercise capacity, muscle strength, and overall health, potentially lowering the risk of heart failure later in life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: live-video-supervised exercise (aerobic + resistance training)
What this could lead to: If it works, this could lead to a safe, home-based exercise program that improves fitness and muscle health in children with Fontan circulation, potentially reducing long-term heart failure risk.
What could go wrong: This is a completed trial, but it was relatively small (150 participants) and focused on short-term fitness gains. It may not prove that exercise reduces death or need for transplant, and results may not apply to all Fontan patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

univentricular heart

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SINGLE-VENTRICLE

Contacts and locations

Locations

Stanford University, Lucile Packard Children Hospital

Palo Alto, California, 94304, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.