SINGLE-VENTRICLE
Clinical trials for SINGLE-VENTRICLE explained in plain language.
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Could a child's own stem cells strengthen a weak heart after surgery?
Disease control Recruiting nowThis study tests whether injecting a child's own heart stem cells (JRM-001) after reconstructive surgery can improve heart function in children with single ventricle heart defects. About 40 children scheduled for Glenn or Fontan surgery will receive either the stem cells or a pla…
Matched conditions: SINGLE-VENTRICLE
Phase: PHASE3 • Sponsor: Metcela Inc. • Aim: Disease control
Last updated Jun 15, 2026 19:07 UTC
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Special baby formula may boost growth in heart defect infants
Disease control Recruiting nowThis study tests whether a high-calorie formula called Fortini helps babies born with a serious heart condition (single ventricle) grow better after their first heart surgery. About 100 infants will be randomly assigned to receive either Fortini or standard high-calorie formula a…
Matched conditions: SINGLE-VENTRICLE
Phase: NA • Sponsor: Driscoll Children's Hospital • Aim: Disease control
Last updated Jun 11, 2026 12:09 UTC
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Digital fitness boost for kids with rare heart condition
Disease control Recruiting nowThis study tests whether a home-based digital exercise program can increase physical activity and fitness in children aged 10-17 with Fontan circulation, a heart condition. Participants will wear an activity tracker for 12 months and complete fitness tests. The goal is to see if …
Matched conditions: SINGLE-VENTRICLE
Phase: NA • Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated Jun 09, 2026 12:06 UTC
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Heart rehab trial aims to boost daily steps in fontan failure patients
Symptom relief Recruiting nowThis study tests whether a cardiac rehabilitation program can help adults with Fontan failure walk more each day and improve their exercise ability, frailty, and quality of life. Researchers will compare the rehab group to those receiving usual care. The trial aims to enroll 50 p…
Matched conditions: SINGLE-VENTRICLE
Phase: NA • Sponsor: Stanford University • Aim: Symptom relief
Last updated Jun 22, 2026 12:04 UTC
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Researchers study digoxin dosing in infants with rare heart condition
Knowledge-focused Recruiting nowThis study looks at how the heart medication digoxin is processed in infants born with single ventricle heart disease. Researchers will collect blood samples during routine care to measure drug levels. The goal is to better understand dosing, but the study does not change the inf…
Matched conditions: SINGLE-VENTRICLE
Phase: PHASE1, PHASE2 • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 23, 2026 11:58 UTC
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Tiny blood samples, big clues: can we predict clots in newborn heart surgery?
Knowledge-focused Recruiting nowThis study will collect leftover blood samples from 10 newborns with severe heart defects who have surgery at Boston Children's Hospital. Researchers want to understand why these babies are more likely to develop dangerous blood clots after surgery. They will look at tiny molecul…
Matched conditions: SINGLE-VENTRICLE
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 23, 2026 11:58 UTC
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New registry tracks heart drug use in adults born with heart defects
Knowledge-focused Recruiting nowThis study is a registry that collects information from 400 adults with congenital heart disease who are taking a class of drugs called SGLT2 inhibitors. Researchers want to understand how these drugs are prescribed, how safe and tolerable they are, and whether they help with hea…
Matched conditions: SINGLE-VENTRICLE
Sponsor: Leiden University Medical Center • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:06 UTC
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New 3D heart scan could improve care for kids with one ventricle
Knowledge-focused Recruiting nowThis study is testing a new 3D ultrasound technique to measure heart size and function in children and young adults born with only one working heart chamber (single ventricle). Researchers will compare the new method to standard tests like echocardiograms and cardiac MRIs. The go…
Matched conditions: SINGLE-VENTRICLE
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:02 UTC